DK0843731T3 - Adenovirusvektorer til genterapi - Google Patents

Adenovirusvektorer til genterapi

Info

Publication number
DK0843731T3
DK0843731T3 DK96909800T DK96909800T DK0843731T3 DK 0843731 T3 DK0843731 T3 DK 0843731T3 DK 96909800 T DK96909800 T DK 96909800T DK 96909800 T DK96909800 T DK 96909800T DK 0843731 T3 DK0843731 T3 DK 0843731T3
Authority
DK
Denmark
Prior art keywords
gene therapy
vectors
adenovirus vectors
adenovirus
novel
Prior art date
Application number
DK96909800T
Other languages
Danish (da)
English (en)
Inventor
Samuel C Wadsworth
Donna Armentano
Helen Romanczuk
Original Assignee
Genzyme Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/409,874 external-priority patent/US5707618A/en
Application filed by Genzyme Corp filed Critical Genzyme Corp
Application granted granted Critical
Publication of DK0843731T3 publication Critical patent/DK0843731T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4712Cystic fibrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/10011Adenoviridae
    • C12N2710/10311Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341Use of virus, viral particle or viral elements as a vector
    • C12N2710/10343Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pulmonology (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Toxicology (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK96909800T 1995-03-24 1996-03-20 Adenovirusvektorer til genterapi DK0843731T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/409,874 US5707618A (en) 1995-03-24 1995-03-24 Adenovirus vectors for gene therapy
US08/540,077 US5824544A (en) 1995-03-24 1995-10-06 Adenovirus vectors for gene therapy
PCT/US1996/003818 WO1996030534A1 (fr) 1995-03-24 1996-03-20 Vecteurs d'adenovirus pour therapie genique

Publications (1)

Publication Number Publication Date
DK0843731T3 true DK0843731T3 (da) 2008-06-09

Family

ID=27020791

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96909800T DK0843731T3 (da) 1995-03-24 1996-03-20 Adenovirusvektorer til genterapi

Country Status (8)

Country Link
EP (1) EP0843731B1 (fr)
JP (1) JP3827163B2 (fr)
AT (1) ATE386130T1 (fr)
AU (1) AU718772B2 (fr)
CA (1) CA2226833C (fr)
DK (1) DK0843731T3 (fr)
ES (1) ES2300105T3 (fr)
WO (1) WO1996030534A1 (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6100086A (en) * 1997-04-14 2000-08-08 Genzyme Corporation Transgene expression systems
US5981275A (en) * 1997-04-14 1999-11-09 Genzyme Corporation Transgene expression system for increased persistence
US6020191A (en) * 1997-04-14 2000-02-01 Genzyme Corporation Adenoviral vectors capable of facilitating increased persistence of transgene expression
FR2774699B1 (fr) * 1997-11-17 2003-10-03 Rhone Poulenc Rorer Sa Methode de reduction des evenements de recombinaison homologue
WO1999057296A1 (fr) * 1998-05-01 1999-11-11 Genzyme Corporation Vecteurs adenoviraux a deletion partielle
CA2721011A1 (fr) 1999-10-22 2001-05-03 Aventis Pasteur Limited Molecule gp100 modifiee et ses applications
WO2001085932A2 (fr) 2000-05-10 2001-11-15 Aventis Pasteur Limited Polypeptides immunogeniques codes par des minigenes mage et leurs utilisations
JP4744771B2 (ja) * 2000-05-26 2011-08-10 大日本住友製薬株式会社 副作用を軽減した新規な組換えアデノウイルスベクター
DE10045687B4 (de) * 2000-09-15 2006-07-06 MICROMUN Privates Institut für Mikrobiologische Forschung GmbH Biotechnikum Greifswald Expressionskassetten und Adenovirusvektoren
US20030026783A1 (en) 2001-08-03 2003-02-06 Amine Abina Method of modulating neutralizing antibodies formation in mammals, and uses thereof in gene therapy, animal transgenesis and in functional inactivation of an endogenous proteins
CN1655827B (zh) 2002-05-27 2010-06-23 佩尔·松内·霍尔姆 腺病毒和编码其的核酸的新应用
US20070110719A1 (en) 2003-11-14 2007-05-17 Holm Per S Novel use of adenoviruses and nucleic acids that code for said viruses
CA2610360A1 (fr) * 2004-12-31 2006-07-06 Per Sonne Holm Adenovirus a region e1 absente et leur utilisation
WO2006070023A2 (fr) 2004-12-31 2006-07-06 Per Sonne Holm Methode d'annulation de la multiresistance dans des cellules animales

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994012649A2 (fr) 1992-12-03 1994-06-09 Genzyme Corporation Therapie genique de la fibrose kystique
PT797676E (pt) * 1993-10-25 2006-05-31 Canji Inc Vector adenoviral recombinante e metodos de utilizacao
DE10234697A1 (de) 2002-07-30 2004-02-19 Morphochem Aktiengesellschaft für kombinatorische Chemie Neue Verbindungen zur Stimulation des Nervenwachstums, zur Inhibition der Narbengewebsbildung und/oder Reduktion eines Sekundärschadens

Also Published As

Publication number Publication date
EP0843731B1 (fr) 2008-02-13
CA2226833C (fr) 2009-12-15
ES2300105T3 (es) 2008-06-01
EP0843731A1 (fr) 1998-05-27
AU718772B2 (en) 2000-04-20
ATE386130T1 (de) 2008-03-15
WO1996030534A1 (fr) 1996-10-03
JPH11506311A (ja) 1999-06-08
JP3827163B2 (ja) 2006-09-27
AU5318496A (en) 1996-10-16
CA2226833A1 (fr) 1996-10-03

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