DK0832097T3 - System og fremgangsmåde til modifikation og rensning af peptider - Google Patents
System og fremgangsmåde til modifikation og rensning af peptiderInfo
- Publication number
- DK0832097T3 DK0832097T3 DK96918342T DK96918342T DK0832097T3 DK 0832097 T3 DK0832097 T3 DK 0832097T3 DK 96918342 T DK96918342 T DK 96918342T DK 96918342 T DK96918342 T DK 96918342T DK 0832097 T3 DK0832097 T3 DK 0832097T3
- Authority
- DK
- Denmark
- Prior art keywords
- modifying
- purifying peptides
- purifying
- peptides
- conjugating
- Prior art date
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
- B01D61/14—Ultrafiltration; Microfiltration
- B01D61/145—Ultrafiltration
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/02—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00279—Features relating to reactor vessels
- B01J2219/00281—Individual reactor vessels
- B01J2219/00283—Reactor vessels with top opening
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00351—Means for dispensing and evacuation of reagents
- B01J2219/00353—Pumps
- B01J2219/00355—Pumps peristaltic
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00479—Means for mixing reactants or products in the reaction vessels
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00718—Type of compounds synthesised
- B01J2219/0072—Organic compounds
- B01J2219/00725—Peptides
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/10—Libraries containing peptides or polypeptides, or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
- C40B60/14—Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Water Supply & Treatment (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/484,740 US6359114B1 (en) | 1995-06-07 | 1995-06-07 | System for method for the modification and purification of proteins |
PCT/US1996/009525 WO1996040733A1 (en) | 1995-06-07 | 1996-06-07 | A system and method for the modification and purification of peptides |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0832097T3 true DK0832097T3 (da) | 2001-11-19 |
Family
ID=23925411
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK96918342T DK0832097T3 (da) | 1995-06-07 | 1996-06-07 | System og fremgangsmåde til modifikation og rensning af peptider |
Country Status (10)
Country | Link |
---|---|
US (2) | US6359114B1 (es) |
EP (1) | EP0832097B1 (es) |
JP (1) | JP3752695B2 (es) |
AT (1) | ATE207931T1 (es) |
AU (1) | AU698179B2 (es) |
DE (1) | DE69616546T2 (es) |
DK (1) | DK0832097T3 (es) |
ES (1) | ES2163025T3 (es) |
PT (1) | PT832097E (es) |
WO (1) | WO1996040733A1 (es) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6359114B1 (en) | 1995-06-07 | 2002-03-19 | Aphton Corp. | System for method for the modification and purification of proteins |
JP2000504692A (ja) * | 1996-02-08 | 2000-04-18 | アフトン・コーポレーション | 胃腸癌治療用の免疫学的方法 |
GB2348155B (en) * | 1997-02-14 | 2000-11-01 | Warner Jenkinson Co Inc | Apparatus for purifying water-insoluble compounds |
GB2337214B (en) * | 1997-02-14 | 2000-09-20 | Warner Jenkinson Co Inc | Method for purifying water-insoluble compounds |
PT968291E (pt) | 1997-02-21 | 2004-06-30 | Genentech Inc | Conjugados de fragmento de anticorpo e polimero |
NZ511550A (en) * | 1997-05-12 | 2005-03-24 | Aphton Corp | CCK-B/gastrin receptor inhibitors for the treatment of tumors |
US20040001842A1 (en) * | 1997-05-12 | 2004-01-01 | Dov Michaeli | Immunogenic compositions to the CCK-B/gastrin receptor and methods for the treatment of tumors |
NL1006071C1 (nl) * | 1997-05-16 | 1998-11-17 | Chemferm Vof | Werkwijze voor het verwijderen van hoogmoleculaire verbindingen uit een processtroom. |
US20030068326A1 (en) * | 1998-05-15 | 2003-04-10 | Aphton Corporation | Method for the treatment of gastroesophageal reflux disease |
ATE361098T1 (de) * | 1998-05-15 | 2007-05-15 | Receptor Biologix Inc | Vorbeugung und behandlung von hypergastrinemie |
GB9909630D0 (en) * | 1999-04-28 | 1999-06-23 | Zeneca Ltd | Reactor |
US6602414B2 (en) * | 2000-03-30 | 2003-08-05 | Formulations Pro | Molecule separation device and method combining multiple filtration media |
WO2002076499A2 (en) * | 2001-03-23 | 2002-10-03 | Aphton Corporation | Combination treatment of pancreatic cancer |
US20090191232A1 (en) * | 2001-05-04 | 2009-07-30 | Gevas Philip C | Combination therapy for the treatment of tumors |
US20030021786A1 (en) * | 2001-07-09 | 2003-01-30 | Gevas Philip C. | Treatment and prevention of cancerous and pre-cancerous conditions of the liver, lung and esophagus |
US20050169979A1 (en) * | 2002-07-03 | 2005-08-04 | Dov Michaeli | Liposomal vaccine |
CA2489919A1 (en) * | 2002-07-03 | 2004-01-15 | Aphton Corporation | Liposomal vaccine |
US20040247661A1 (en) * | 2002-07-03 | 2004-12-09 | Dov Michaeli | Liposomal vaccine |
WO2004088326A2 (en) | 2003-03-28 | 2004-10-14 | Aphton Corporation | Gastrin hormone immunoassays |
EP1730193A2 (en) * | 2004-03-29 | 2006-12-13 | Receptor Biologix, Inc. | Monoclonal antibodies to gastrin hormone |
WO2006032980A1 (en) * | 2004-09-22 | 2006-03-30 | Receptor Biologix, Inc. | Monoclonal antibolies to progastrin |
EP2552496A4 (en) * | 2010-03-26 | 2013-12-04 | Ge Healthcare Bio Sciences | STERILIZATION PROCESS |
EP2682168A1 (en) | 2012-07-02 | 2014-01-08 | Millipore Corporation | Purification of biological molecules |
WO2014137903A2 (en) | 2013-03-08 | 2014-09-12 | Genzyme Corporation | Integrated continuous manufacturing of therapeutic protein drug substances |
TWI709569B (zh) | 2014-01-17 | 2020-11-11 | 美商健臻公司 | 無菌層析樹脂及其用於製造方法的用途 |
TWI671312B (zh) | 2014-01-17 | 2019-09-11 | 美商健臻公司 | 無菌層析法及製法 |
EP3015542A1 (de) * | 2015-05-07 | 2016-05-04 | Bayer Technology Services GmbH | Modulare anlage und verfahren zur kontinuierlichen, keimreduzierten produktion und/oder aufbereitung eines produktes |
CA3066756A1 (en) | 2017-06-15 | 2018-12-20 | Cancer Advances Inc. | Compositions and methods for inducing humoral and cellular immunities against tumors and cancer |
US11369703B2 (en) | 2018-08-31 | 2022-06-28 | Genzyme Corporation | Sterile chromatography resin and use thereof in manufacturing processes |
EP3939691B1 (en) * | 2020-07-13 | 2023-11-22 | Sartorius Stedim Biotech GmbH | Device assembly for producing bioconjugates |
WO2023034490A2 (en) * | 2021-09-02 | 2023-03-09 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | A hierarchically organized system for contemporaneous fractionation of multiple fractions |
Family Cites Families (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4762913A (en) | 1973-05-07 | 1988-08-09 | The Ohio State University | Antigenic modification of polypeptides |
US5006334A (en) | 1973-05-07 | 1991-04-09 | The Ohio State University | Antigenic modification of polypeptides |
SE434914B (sv) * | 1975-07-07 | 1984-08-27 | Jonsson U R S | Forfarande for att ur en suspension av bakterier och ett vetskeformigt medium genom filtrering avskilja mediet under samtidig anrikning av bakterierna |
US4042682A (en) | 1976-04-07 | 1977-08-16 | Hoffmann-La Roche Inc. | Endogenous morphine-like compound |
US4385113A (en) * | 1978-03-20 | 1983-05-24 | Nasa | Rapid, quantitative determination of bacteria in water |
US4443540A (en) * | 1980-05-09 | 1984-04-17 | University Of Illinois Foundation | Protein hydrolysis |
IL64501A (en) | 1980-12-22 | 1985-07-31 | Astra Laekemedel Ab | 9-substituted 4-hydroxybutyl guanine derivatives,their preparation and antiviral use |
US4608336A (en) | 1981-08-27 | 1986-08-26 | Miles Laboratories, Inc. | #3B theophylline immunoassay employing 9-theophylline reagents |
DE3144705C2 (de) * | 1981-11-11 | 1983-12-08 | Biotest-Serum-Institut Gmbh, 6000 Frankfurt | Verfahren zur Herstellung eines lagerstabilen, vernetzten Hämoglobinpräparates mit hoher Sauerstoff-Transportkapazität, sowie das nach diesem Verfahren hergestellte Hämoglobinpräparat |
US4420425A (en) * | 1982-08-02 | 1983-12-13 | The Texas A&M University System | Method for processing protein from nonbinding oilseed by ultrafiltration and solubilization |
US4414113A (en) * | 1982-09-29 | 1983-11-08 | Ecodyne Corporation | Liquid purification using reverse osmosis hollow fibers |
US4609662A (en) | 1982-10-14 | 1986-09-02 | Burroughs Wellcome Co. | Method for using purine derivatives |
US4621140A (en) | 1984-02-23 | 1986-11-04 | Syntex (U.S.A.) Inc. | Process for preparing 2,6-substituted-9-(1,3-dihydroxy-2-propoxymethyl)-purines and certain derivatives |
US4605500A (en) * | 1984-04-24 | 1986-08-12 | Mitsubishi Rayon Co., Ltd. | Hollow-fiber filter module |
US5024762A (en) * | 1985-03-05 | 1991-06-18 | Memtec Limited | Concentration of solids in a suspension |
US4701304A (en) * | 1985-04-19 | 1987-10-20 | Applied Protein Technologies, Inc. | Apparatus for automated synthesis of peptides |
US4803170A (en) | 1985-05-09 | 1989-02-07 | Ultra Diagnostics Corporation | Competitive immunoassay method, device and test kit |
US5106734A (en) | 1986-04-30 | 1992-04-21 | Novo Nordisk A/S | Process of using light absorption to control enzymatic depolymerization of heparin to produce low molecular weight heparin |
IE64511B1 (en) | 1988-03-11 | 1995-08-09 | Takeda Chemical Industries Ltd | Automated synthesizing apparatus |
US5262053A (en) * | 1988-07-15 | 1993-11-16 | Filtrox-Werk Ag | Filtration process, use of stabilizers installation for a filtration process, and procedure for operating said installation |
US5683916A (en) * | 1988-10-31 | 1997-11-04 | Hemasure Inc. | Membrane affinity apparatus and purification methods related thereto |
US5023077A (en) * | 1989-01-24 | 1991-06-11 | Aphton Corporation | Immunogenic compositions and methods for the treatment and prevention of gastric and duodenal ulcer disease |
US4986918A (en) * | 1989-11-08 | 1991-01-22 | Romicon Inc. | Membrane separation system and method of operation |
FR2666245B1 (fr) * | 1990-08-31 | 1992-10-23 | Lyonnaise Eaux | Procede de commande des modes de fonctionnement d'un appareil automatique de filtration d'eau sur membranes tubulaires. |
IL95561A0 (en) | 1990-09-02 | 1991-06-30 | Weizmann Kiryat Membrane Prod | Method for the purification and concentration of biologically active materials |
US5256294A (en) | 1990-09-17 | 1993-10-26 | Genentech, Inc. | Tangential flow filtration process and apparatus |
US5132015A (en) * | 1990-10-04 | 1992-07-21 | Rohm And Haas Company | Flow control for ultra filtration systems |
US5171767A (en) * | 1991-05-06 | 1992-12-15 | Rohm And Haas Company | Utrafiltration process for the recovery of polymeric latices from whitewater |
US5227071A (en) * | 1992-01-17 | 1993-07-13 | Madison Chemical Company, Inc. | Method and apparatus for processing oily wastewater |
US5188733A (en) | 1992-02-26 | 1993-02-23 | Trustees Of Boston University | Apparatus and process for effecting sequential peptide syntheses |
GB9210980D0 (en) * | 1992-05-22 | 1992-07-08 | Dow Danmark | Cassette membrane system and method of use for low pressure separations |
US5380495A (en) * | 1993-08-27 | 1995-01-10 | Chang; Heng-Wei | Solid phase peptide synthesizer |
US5525235A (en) * | 1994-05-17 | 1996-06-11 | Energy Biosystems Corporation | Method for separating a petroleum containing emulsion |
US6359114B1 (en) | 1995-06-07 | 2002-03-19 | Aphton Corp. | System for method for the modification and purification of proteins |
US6027853A (en) * | 1998-01-16 | 2000-02-22 | Olin Microelectronic Chemicals, Inc. | Process for preparing a radiation-sensitive composition |
-
1995
- 1995-06-07 US US08/484,740 patent/US6359114B1/en not_active Expired - Lifetime
-
1996
- 1996-06-07 WO PCT/US1996/009525 patent/WO1996040733A1/en active IP Right Grant
- 1996-06-07 EP EP96918342A patent/EP0832097B1/en not_active Expired - Lifetime
- 1996-06-07 DE DE69616546T patent/DE69616546T2/de not_active Expired - Lifetime
- 1996-06-07 AT AT96918342T patent/ATE207931T1/de not_active IP Right Cessation
- 1996-06-07 PT PT96918342T patent/PT832097E/pt unknown
- 1996-06-07 AU AU61029/96A patent/AU698179B2/en not_active Expired
- 1996-06-07 JP JP50182897A patent/JP3752695B2/ja not_active Expired - Lifetime
- 1996-06-07 DK DK96918342T patent/DK0832097T3/da active
- 1996-06-07 ES ES96918342T patent/ES2163025T3/es not_active Expired - Lifetime
-
2002
- 2002-03-15 US US10/098,690 patent/US20020095028A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
AU698179B2 (en) | 1998-10-29 |
US20020095028A1 (en) | 2002-07-18 |
PT832097E (pt) | 2002-04-29 |
US6359114B1 (en) | 2002-03-19 |
JP3752695B2 (ja) | 2006-03-08 |
ES2163025T3 (es) | 2002-01-16 |
DE69616546T2 (de) | 2002-05-02 |
DE69616546D1 (de) | 2001-12-06 |
AU6102996A (en) | 1996-12-30 |
JPH11507348A (ja) | 1999-06-29 |
ATE207931T1 (de) | 2001-11-15 |
WO1996040733A1 (en) | 1996-12-19 |
EP0832097A1 (en) | 1998-04-01 |
EP0832097B1 (en) | 2001-10-31 |
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