DK0831881T3 - CETP til forøgelse af HDL-cholesterolniveau - Google Patents
CETP til forøgelse af HDL-cholesterolniveauInfo
- Publication number
- DK0831881T3 DK0831881T3 DK96918201T DK96918201T DK0831881T3 DK 0831881 T3 DK0831881 T3 DK 0831881T3 DK 96918201 T DK96918201 T DK 96918201T DK 96918201 T DK96918201 T DK 96918201T DK 0831881 T3 DK0831881 T3 DK 0831881T3
- Authority
- DK
- Denmark
- Prior art keywords
- cetp
- hdl cholesterol
- cholesterol levels
- increase hdl
- stimulating
- Prior art date
Links
- KEWSCDNULKOKTG-UHFFFAOYSA-N 4-cyano-4-ethylsulfanylcarbothioylsulfanylpentanoic acid Chemical compound CCSC(=S)SC(C)(C#N)CCC(O)=O KEWSCDNULKOKTG-UHFFFAOYSA-N 0.000 title abstract 5
- 102100037637 Cholesteryl ester transfer protein Human genes 0.000 title abstract 5
- 101000880514 Homo sapiens Cholesteryl ester transfer protein Proteins 0.000 title abstract 5
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 title abstract 4
- 230000028993 immune response Effects 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 230000004936 stimulating effect Effects 0.000 abstract 2
- 241000124008 Mammalia Species 0.000 abstract 1
- 108010058846 Ovalbumin Proteins 0.000 abstract 1
- 239000002671 adjuvant Substances 0.000 abstract 1
- 235000012000 cholesterol Nutrition 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 230000003053 immunization Effects 0.000 abstract 1
- 230000005847 immunogenicity Effects 0.000 abstract 1
- 229940092253 ovalbumin Drugs 0.000 abstract 1
- 230000004044 response Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- General Chemical & Material Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Obesity (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Color Television Image Signal Generators (AREA)
- Materials For Photolithography (AREA)
- Ink Jet Recording Methods And Recording Media Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US48245495A | 1995-06-06 | 1995-06-06 | |
| PCT/US1996/009143 WO1996039168A1 (fr) | 1995-06-06 | 1996-06-05 | Procede permettant d'accroitre le taux de cholesterol des lphd |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0831881T3 true DK0831881T3 (da) | 2003-07-07 |
Family
ID=23916145
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK96918201T DK0831881T3 (da) | 1995-06-06 | 1996-06-05 | CETP til forøgelse af HDL-cholesterolniveau |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7074407B1 (fr) |
| EP (1) | EP0831881B1 (fr) |
| JP (1) | JP3910635B2 (fr) |
| AT (1) | ATE234109T1 (fr) |
| CA (1) | CA2223177A1 (fr) |
| DE (1) | DE69626642T2 (fr) |
| DK (1) | DK0831881T3 (fr) |
| ES (1) | ES2190470T3 (fr) |
| WO (1) | WO1996039168A1 (fr) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6410022B1 (en) | 1995-05-01 | 2002-06-25 | Avant Immunotherapeutics, Inc. | Modulation of cholesteryl ester transfer protein (CETP) activity |
| EP0831881B1 (fr) | 1995-06-06 | 2003-03-12 | Avant Immunotherapeutics, Inc. | Cetp pour accroitre le taux de cholesterol des lphd |
| US6284533B1 (en) | 1996-05-01 | 2001-09-04 | Avant Immunotherapeutics, Inc. | Plasmid-based vaccine for treating atherosclerosis |
| US6846808B1 (en) | 1996-05-01 | 2005-01-25 | Avant Immunotherapeutics, Inc. | Plasmid-based vaccine for treating atherosclerosis |
| EP1024825A1 (fr) * | 1997-10-20 | 2000-08-09 | Avant Immunotherapeutics, Inc. | Proteine de transfert de l'ester de cholesteryle xenogenique et procede de modulation de l'activite de cette proteine |
| US6300308B1 (en) * | 1997-12-31 | 2001-10-09 | Board Of Regents, The University Of Texas System | Methods and compositions for inducing autoimmunity in the treatment of cancers |
| WO2002032935A1 (fr) * | 1999-12-13 | 2002-04-25 | Universidad Nacional Autonoma De Mexico | Méthode immunoenzymatique de quantification |
| MX347400B (es) * | 2012-06-29 | 2017-04-18 | Univ Nac Autónoma De México | Vacuna de aplicacion nasal contra el desarrollo de la enfermedad aterosclerotica y el higado graso. |
| CN105859837B (zh) | 2014-10-22 | 2020-11-20 | 台北医学大学 | 胆固醇酯转运蛋白抗原肽和融合蛋白以及其组合物和应用 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6143305A (en) | 1973-05-07 | 2000-11-07 | The Ohio State University | Antigenically modified polypeptides composition |
| US5126399A (en) | 1986-04-30 | 1992-06-30 | Board Of Regents, The University Of Texas System | Methods and compositions for the preparation and use of site-directed immunologic reagents |
| US5338829A (en) | 1988-04-20 | 1994-08-16 | Trustees Of The University Of Pennsylvania | Peptides derived from human immunodeficiency virus-1 GP160 |
| GB8812214D0 (en) | 1988-05-24 | 1988-06-29 | Hoffmann La Roche | Use of peptide from circumsporozoite protein of p falciparum as universally recognized t-cell epitope |
| US5242687A (en) | 1989-03-15 | 1993-09-07 | Tkb Associates Limited Partnership | Method of reducing cellular immune response involving T-cells using CD8-bearing antigen presenting cells |
| US5264341A (en) * | 1989-08-30 | 1993-11-23 | Eli Lilly And Company | Selective cloning for high monoclonal antibody secreting hybridomas |
| EP0562020A4 (en) | 1990-12-10 | 1993-11-18 | Alving, Carl L. | A vaccine against cholesterol to prevent hypercholesterolemia and atherosclerosis |
| EP0618803A4 (fr) * | 1991-12-19 | 1995-03-22 | Southwest Found Biomed Res | Polypeptide inhibant la proteine de transfert aux esters de cholesteryl, anticorps contre le polypeptide synthetique et traitements prophylactiques et therapeutiques anti-atherosclerose. |
| AU4377793A (en) | 1992-05-20 | 1993-12-13 | Johns Hopkins University, The | Alternative receptor therapy |
| US5279540A (en) | 1992-09-24 | 1994-01-18 | Davidson Michael H | Method for reducing the risk of atherosclerosis |
| US5618683A (en) | 1993-04-13 | 1997-04-08 | Brocia; Robert W. | Diagnostic kit for cholesteryl ester transfer protein (CETP) activity measurement and a new synthetic particle used therein |
| CA2161445C (fr) | 1993-04-27 | 2009-06-30 | Anna Efim Ladd | Peptides de lhrh immunogenes et stimulateurs universels synthetiques de l'immunite pour les vaccins |
| US5759551A (en) | 1993-04-27 | 1998-06-02 | United Biomedical, Inc. | Immunogenic LHRH peptide constructs and synthetic universal immune stimulators for vaccines |
| WO1995004755A1 (fr) * | 1993-08-04 | 1995-02-16 | Southwest Foundation For Biomedical Research | Polypeptide inhibiteur de cetp, anticorps contre ce polypeptide synthetique et traitements prophylactique et therapeutique de l'atherosclerose |
| DK96493D0 (da) | 1993-08-26 | 1993-08-26 | Mouritsen Og Elsner Aps | Fremgangsmaade til at inducere antistofresponser mod selvproteiner og autovaccine fremstillet ved fremgangsmaaden |
| JPH09501186A (ja) | 1994-11-12 | 1997-02-04 | 株式会社エルジ化学 | コレステリルエステル運搬蛋白質阻害ペプチドおよびこれを含む動脈硬化症のための予防および治療剤 |
| US5705388A (en) | 1994-12-23 | 1998-01-06 | Ribozyme Pharmaceuticals, Inc. | CETP Ribozymes |
| US6410022B1 (en) | 1995-05-01 | 2002-06-25 | Avant Immunotherapeutics, Inc. | Modulation of cholesteryl ester transfer protein (CETP) activity |
| EP0831881B1 (fr) | 1995-06-06 | 2003-03-12 | Avant Immunotherapeutics, Inc. | Cetp pour accroitre le taux de cholesterol des lphd |
| AU721729B2 (en) | 1996-05-01 | 2000-07-13 | Avant Immunotherapeutics, Inc. | Plasmid-based vaccine for treating atherosclerosis |
| US6284533B1 (en) | 1996-05-01 | 2001-09-04 | Avant Immunotherapeutics, Inc. | Plasmid-based vaccine for treating atherosclerosis |
| US5994310A (en) | 1998-09-03 | 1999-11-30 | Bayer Corporation | Peptide ligands for affinity purification of human Factor VIII |
-
1996
- 1996-06-05 EP EP96918201A patent/EP0831881B1/fr not_active Expired - Lifetime
- 1996-06-05 DE DE69626642T patent/DE69626642T2/de not_active Expired - Fee Related
- 1996-06-05 CA CA002223177A patent/CA2223177A1/fr not_active Abandoned
- 1996-06-05 ES ES96918201T patent/ES2190470T3/es not_active Expired - Lifetime
- 1996-06-05 AT AT96918201T patent/ATE234109T1/de not_active IP Right Cessation
- 1996-06-05 WO PCT/US1996/009143 patent/WO1996039168A1/fr active IP Right Grant
- 1996-06-05 DK DK96918201T patent/DK0831881T3/da active
- 1996-06-05 JP JP50153397A patent/JP3910635B2/ja not_active Expired - Fee Related
-
2000
- 2000-03-10 US US09/523,033 patent/US7074407B1/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US7074407B1 (en) | 2006-07-11 |
| ATE234109T1 (de) | 2003-03-15 |
| EP0831881A1 (fr) | 1998-04-01 |
| EP0831881B1 (fr) | 2003-03-12 |
| AU6091296A (en) | 1996-12-24 |
| DE69626642D1 (de) | 2003-04-17 |
| JP3910635B2 (ja) | 2007-04-25 |
| WO1996039168A1 (fr) | 1996-12-12 |
| ES2190470T3 (es) | 2003-08-01 |
| DE69626642T2 (de) | 2004-01-29 |
| AU715410B2 (en) | 2000-02-03 |
| CA2223177A1 (fr) | 1996-12-12 |
| JPH11507910A (ja) | 1999-07-13 |
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