DE69626642D1 - Cetp zur erhöhung des hdl-cholesterol-gehalts - Google Patents
Cetp zur erhöhung des hdl-cholesterol-gehaltsInfo
- Publication number
- DE69626642D1 DE69626642D1 DE69626642T DE69626642T DE69626642D1 DE 69626642 D1 DE69626642 D1 DE 69626642D1 DE 69626642 T DE69626642 T DE 69626642T DE 69626642 T DE69626642 T DE 69626642T DE 69626642 D1 DE69626642 D1 DE 69626642D1
- Authority
- DE
- Germany
- Prior art keywords
- cetp
- hdl cholesterol
- increasing
- cholesterol content
- stimulating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- KEWSCDNULKOKTG-UHFFFAOYSA-N 4-cyano-4-ethylsulfanylcarbothioylsulfanylpentanoic acid Chemical compound CCSC(=S)SC(C)(C#N)CCC(O)=O KEWSCDNULKOKTG-UHFFFAOYSA-N 0.000 title abstract 5
- 102100037637 Cholesteryl ester transfer protein Human genes 0.000 title abstract 5
- 101000880514 Homo sapiens Cholesteryl ester transfer protein Proteins 0.000 title abstract 5
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 title abstract 4
- 235000012000 cholesterol Nutrition 0.000 title abstract 2
- 230000028993 immune response Effects 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 230000004936 stimulating effect Effects 0.000 abstract 2
- 241000124008 Mammalia Species 0.000 abstract 1
- 108010058846 Ovalbumin Proteins 0.000 abstract 1
- 239000002671 adjuvant Substances 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 230000003053 immunization Effects 0.000 abstract 1
- 230000005847 immunogenicity Effects 0.000 abstract 1
- 229940092253 ovalbumin Drugs 0.000 abstract 1
- 230000004044 response Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Public Health (AREA)
- Toxicology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Ink Jet Recording Methods And Recording Media Thereof (AREA)
- Color Television Image Signal Generators (AREA)
- Materials For Photolithography (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US48245495A | 1995-06-06 | 1995-06-06 | |
| PCT/US1996/009143 WO1996039168A1 (en) | 1995-06-06 | 1996-06-05 | Method for increasing hdl cholesterol level |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69626642D1 true DE69626642D1 (de) | 2003-04-17 |
| DE69626642T2 DE69626642T2 (de) | 2004-01-29 |
Family
ID=23916145
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69626642T Expired - Fee Related DE69626642T2 (de) | 1995-06-06 | 1996-06-05 | Cetp zur erhöhung des hdl-cholesterol-gehalts |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7074407B1 (de) |
| EP (1) | EP0831881B1 (de) |
| JP (1) | JP3910635B2 (de) |
| AT (1) | ATE234109T1 (de) |
| CA (1) | CA2223177A1 (de) |
| DE (1) | DE69626642T2 (de) |
| DK (1) | DK0831881T3 (de) |
| ES (1) | ES2190470T3 (de) |
| WO (1) | WO1996039168A1 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6410022B1 (en) | 1995-05-01 | 2002-06-25 | Avant Immunotherapeutics, Inc. | Modulation of cholesteryl ester transfer protein (CETP) activity |
| WO1996039168A1 (en) | 1995-06-06 | 1996-12-12 | The Immune Response Corporation | Method for increasing hdl cholesterol level |
| US6284533B1 (en) | 1996-05-01 | 2001-09-04 | Avant Immunotherapeutics, Inc. | Plasmid-based vaccine for treating atherosclerosis |
| US6846808B1 (en) | 1996-05-01 | 2005-01-25 | Avant Immunotherapeutics, Inc. | Plasmid-based vaccine for treating atherosclerosis |
| AU747709B2 (en) * | 1997-10-20 | 2002-05-23 | Avant Immunotherapeutics, Inc. | Xenogeneic cholesteryl ester transfer protein (CETP) for modulation of CETP activity |
| US6300308B1 (en) * | 1997-12-31 | 2001-10-09 | Board Of Regents, The University Of Texas System | Methods and compositions for inducing autoimmunity in the treatment of cancers |
| DE60036132T2 (de) * | 1999-12-13 | 2008-08-21 | Universidad Nacional Autonoma De Mexico | Quantitative immunoenzymatische messmethode |
| MX347400B (es) * | 2012-06-29 | 2017-04-18 | Univ Nac Autónoma De México | Vacuna de aplicacion nasal contra el desarrollo de la enfermedad aterosclerotica y el higado graso. |
| CN105859837B (zh) | 2014-10-22 | 2020-11-20 | 台北医学大学 | 胆固醇酯转运蛋白抗原肽和融合蛋白以及其组合物和应用 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6143305A (en) | 1973-05-07 | 2000-11-07 | The Ohio State University | Antigenically modified polypeptides composition |
| US5126399A (en) | 1986-04-30 | 1992-06-30 | Board Of Regents, The University Of Texas System | Methods and compositions for the preparation and use of site-directed immunologic reagents |
| US5338829A (en) | 1988-04-20 | 1994-08-16 | Trustees Of The University Of Pennsylvania | Peptides derived from human immunodeficiency virus-1 GP160 |
| GB8812214D0 (en) | 1988-05-24 | 1988-06-29 | Hoffmann La Roche | Use of peptide from circumsporozoite protein of p falciparum as universally recognized t-cell epitope |
| US5242687A (en) | 1989-03-15 | 1993-09-07 | Tkb Associates Limited Partnership | Method of reducing cellular immune response involving T-cells using CD8-bearing antigen presenting cells |
| US5264341A (en) * | 1989-08-30 | 1993-11-23 | Eli Lilly And Company | Selective cloning for high monoclonal antibody secreting hybridomas |
| JP3183665B2 (ja) | 1990-12-10 | 2001-07-09 | エントルメド インコーポレーテッド | コレステロール過剰血症およびアテローム性動脈硬化を防止するためのコレステロールに体するワクチン |
| EP0618803A4 (de) * | 1991-12-19 | 1995-03-22 | Southwest Found Biomed Res | Polypeptide als inhibitoren gegen cholesterylester-transferase, antikörper gegen die synthetischen polypeptide und prophylaktische und therapeutische behandlungsweisen der atherosklerose. |
| WO1993023076A1 (en) | 1992-05-20 | 1993-11-25 | The Johns-Hopkins University | Alternative receptor therapy |
| US5279540A (en) | 1992-09-24 | 1994-01-18 | Davidson Michael H | Method for reducing the risk of atherosclerosis |
| US5618683A (en) | 1993-04-13 | 1997-04-08 | Brocia; Robert W. | Diagnostic kit for cholesteryl ester transfer protein (CETP) activity measurement and a new synthetic particle used therein |
| US5759551A (en) | 1993-04-27 | 1998-06-02 | United Biomedical, Inc. | Immunogenic LHRH peptide constructs and synthetic universal immune stimulators for vaccines |
| EP0708656B1 (de) | 1993-04-27 | 2002-07-31 | United Biomedical, Inc. | Immunogene lhrh peptidkonstrukion und synthetische, universale immunstimulatoren als impfstoffe |
| KR950703580A (ko) * | 1993-08-04 | 1995-09-20 | 프랭크 에프. 레드포드, 쥬니어 | CETP 억제 폴리펩티드, 그 합성 폴리펩티드에 대한 항체 및 아테롬성 동맥경화증의 예방학적 및 치료학적 처치(CETP Inhibitor Polypeptide, Antibodies against the Synthetic Polypeptide and Prophylactic and Therapeutic AntiAtheroselerosis Treatments) |
| DK96493D0 (da) | 1993-08-26 | 1993-08-26 | Mouritsen Og Elsner Aps | Fremgangsmaade til at inducere antistofresponser mod selvproteiner og autovaccine fremstillet ved fremgangsmaaden |
| KR100204738B1 (ko) | 1994-11-12 | 1999-06-15 | 성재갑 | 콜레스테릴 에스테르 전달 단백질 저해 펩티드 및 이를 포함하는 동맥경화증 예방 및 치료제 |
| US5705388A (en) | 1994-12-23 | 1998-01-06 | Ribozyme Pharmaceuticals, Inc. | CETP Ribozymes |
| US6410022B1 (en) | 1995-05-01 | 2002-06-25 | Avant Immunotherapeutics, Inc. | Modulation of cholesteryl ester transfer protein (CETP) activity |
| WO1996039168A1 (en) | 1995-06-06 | 1996-12-12 | The Immune Response Corporation | Method for increasing hdl cholesterol level |
| ATE321559T1 (de) | 1996-05-01 | 2006-04-15 | Avant Immunotherapeutics Inc | Impfstoff auf einem plasmid beruhend zur behandlung von atherosclerosis |
| US6284533B1 (en) | 1996-05-01 | 2001-09-04 | Avant Immunotherapeutics, Inc. | Plasmid-based vaccine for treating atherosclerosis |
| US5994310A (en) | 1998-09-03 | 1999-11-30 | Bayer Corporation | Peptide ligands for affinity purification of human Factor VIII |
-
1996
- 1996-06-05 WO PCT/US1996/009143 patent/WO1996039168A1/en active IP Right Grant
- 1996-06-05 DE DE69626642T patent/DE69626642T2/de not_active Expired - Fee Related
- 1996-06-05 ES ES96918201T patent/ES2190470T3/es not_active Expired - Lifetime
- 1996-06-05 JP JP50153397A patent/JP3910635B2/ja not_active Expired - Fee Related
- 1996-06-05 EP EP96918201A patent/EP0831881B1/de not_active Expired - Lifetime
- 1996-06-05 CA CA002223177A patent/CA2223177A1/en not_active Abandoned
- 1996-06-05 DK DK96918201T patent/DK0831881T3/da active
- 1996-06-05 AT AT96918201T patent/ATE234109T1/de not_active IP Right Cessation
-
2000
- 2000-03-10 US US09/523,033 patent/US7074407B1/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ES2190470T3 (es) | 2003-08-01 |
| CA2223177A1 (en) | 1996-12-12 |
| JP3910635B2 (ja) | 2007-04-25 |
| US7074407B1 (en) | 2006-07-11 |
| EP0831881B1 (de) | 2003-03-12 |
| EP0831881A1 (de) | 1998-04-01 |
| AU715410B2 (en) | 2000-02-03 |
| DK0831881T3 (da) | 2003-07-07 |
| JPH11507910A (ja) | 1999-07-13 |
| AU6091296A (en) | 1996-12-24 |
| DE69626642T2 (de) | 2004-01-29 |
| WO1996039168A1 (en) | 1996-12-12 |
| ATE234109T1 (de) | 2003-03-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |