DK0831090T3 - N-substituerede cykliske aminer, fremgangsmåde til fremstilling heraf og farmaceutiske sammensætninger indeholdende dem - Google Patents

N-substituerede cykliske aminer, fremgangsmåde til fremstilling heraf og farmaceutiske sammensætninger indeholdende dem

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Publication number
DK0831090T3
DK0831090T3 DK97402175T DK97402175T DK0831090T3 DK 0831090 T3 DK0831090 T3 DK 0831090T3 DK 97402175 T DK97402175 T DK 97402175T DK 97402175 T DK97402175 T DK 97402175T DK 0831090 T3 DK0831090 T3 DK 0831090T3
Authority
DK
Denmark
Prior art keywords
halo
saturated
optionally substituted
unsaturated
substituted
Prior art date
Application number
DK97402175T
Other languages
English (en)
Inventor
Alain Dhainaut
Andre Tizot
Emmanuel Canet
Michel Lonchampt
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Application granted granted Critical
Publication of DK0831090T3 publication Critical patent/DK0831090T3/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
DK97402175T 1996-09-20 1997-09-19 N-substituerede cykliske aminer, fremgangsmåde til fremstilling heraf og farmaceutiske sammensætninger indeholdende dem DK0831090T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9611501A FR2753706B1 (fr) 1996-09-20 1996-09-20 Nouvelles amines cycliques n-substituees, leur procede de preparation et les compositions pharmaceutiques les renfermant

Publications (1)

Publication Number Publication Date
DK0831090T3 true DK0831090T3 (da) 2000-09-11

Family

ID=9495928

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97402175T DK0831090T3 (da) 1996-09-20 1997-09-19 N-substituerede cykliske aminer, fremgangsmåde til fremstilling heraf og farmaceutiske sammensætninger indeholdende dem

Country Status (18)

Country Link
US (1) US5919801A (da)
EP (1) EP0831090B1 (da)
JP (1) JPH10101645A (da)
AT (1) ATE191717T1 (da)
AU (1) AU718489B2 (da)
BR (1) BR9704757A (da)
CA (1) CA2216664C (da)
DE (1) DE69701662T2 (da)
DK (1) DK0831090T3 (da)
ES (1) ES2147427T3 (da)
FR (1) FR2753706B1 (da)
GR (1) GR3033509T3 (da)
HU (1) HU221811B1 (da)
NO (1) NO313997B1 (da)
NZ (1) NZ328789A (da)
PL (1) PL322192A1 (da)
PT (1) PT831090E (da)
ZA (1) ZA978462B (da)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6867209B1 (en) 1998-05-22 2005-03-15 Scios, Inc. Indole-type derivatives as inhibitors of p38 kinase
HUP0203657A3 (en) * 1998-05-22 2005-03-29 Scios Inc Sunnyvale Heterocyclic compounds and methods to treat cardiac failure and other disorders
US6130235A (en) * 1998-05-22 2000-10-10 Scios Inc. Compounds and methods to treat cardiac failure and other disorders
US6340685B1 (en) 1998-05-22 2002-01-22 Scios, Inc. Compounds and methods to treat cardiac failure and other disorders
US6448257B1 (en) 1998-05-22 2002-09-10 Scios, Inc. Compounds and methods to treat cardiac failure and other disorders
US6589954B1 (en) 1998-05-22 2003-07-08 Scios, Inc. Compounds and methods to treat cardiac failure and other disorders
AU754379B2 (en) 1998-08-26 2002-11-14 Smithkline Beecham Corporation Therapies for treating pulmonary diseases
IL146309A (en) 1999-05-21 2008-03-20 Scios Inc Derivatives of the indole type and pharmaceutical preparations containing them as inhibitors of kinase p38
KR100515905B1 (ko) * 2000-01-31 2005-09-21 주식회사 엘지생명과학 피롤아미드의 새로운 제조방법
MXPA02007688A (es) * 2000-02-08 2002-12-13 Smithkline Beecham Corp Metodo y composiciones para tratar una enfermedad antiinflamatoria.
US20030207845A1 (en) * 2001-02-08 2003-11-06 Keating Elizabeth T. Method and compositions for treating an inflammatory disease
DE10035928A1 (de) 2000-07-21 2002-03-07 Asta Medica Ag Neue Heteroaryl-Derivate und deren Verwendung als Arzneimittel
DE10035927A1 (de) 2000-07-21 2002-03-07 Asta Medica Ag Neue Heteroaryl-Derivate und deren Verwendung als Arzneimittel
CA2418313C (en) * 2000-08-11 2008-09-23 Ono Pharmaceutical Co., Ltd. Piperidine derivatives and agent comprising the derivative as active ingredient
US20040219552A1 (en) * 2001-08-14 2004-11-04 Ali Ait Ikhlef Novel molecular target for neurotoxicity
FR2856595B1 (fr) * 2003-06-27 2008-05-30 Exonhit Therapeutics Sa Methodes et compositions pour le traitement de deficits cognitifs.
EP2674417A3 (en) * 2007-11-21 2014-04-09 Decode Genetics EHF Biaryl PDE4 inhibitors for treating inflammation

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR6850M (da) * 1967-12-05 1969-04-08
US5459151A (en) * 1993-04-30 1995-10-17 American Home Products Corporation N-acyl substituted phenyl piperidines as bronchodilators and antiinflammatory agents
US5434158A (en) * 1994-04-26 1995-07-18 Merck & Co., Inc. Spiro-substituted azacycles as neurokinin-3 antagonists
US5530012A (en) * 1994-12-22 1996-06-25 Bristol-Myers Squibb Co. 3-alkoxybenzylpiperidine derivatives as melatonergic agents
US5703239A (en) * 1995-06-02 1997-12-30 Bristol-Myers Squibb Company Indanylpiperidines as melatonergic agents

Also Published As

Publication number Publication date
HU9701561D0 (en) 1997-11-28
ATE191717T1 (de) 2000-04-15
CA2216664C (fr) 2002-05-21
CA2216664A1 (fr) 1998-03-20
DE69701662D1 (de) 2000-05-18
HUP9701561A2 (hu) 1998-05-28
PT831090E (pt) 2000-07-31
US5919801A (en) 1999-07-06
PL322192A1 (en) 1998-03-30
AU718489B2 (en) 2000-04-13
FR2753706B1 (fr) 1998-10-30
BR9704757A (pt) 1998-09-01
HUP9701561A3 (en) 1998-07-28
NO974253D0 (no) 1997-09-15
GR3033509T3 (en) 2000-09-29
EP0831090B1 (fr) 2000-04-12
NO313997B1 (no) 2003-01-13
NZ328789A (en) 1998-02-26
EP0831090A1 (fr) 1998-03-25
DE69701662T2 (de) 2000-11-23
ES2147427T3 (es) 2000-09-01
HU221811B1 (hu) 2003-01-28
FR2753706A1 (fr) 1998-03-27
NO974253L (no) 1998-03-23
JPH10101645A (ja) 1998-04-21
ZA978462B (en) 1998-03-24
AU3836297A (en) 1998-03-26

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