DK0817786T3 - Substituerede tetronsyrer, der er nyttige til behandling af HIV og andre retrovira - Google Patents

Substituerede tetronsyrer, der er nyttige til behandling af HIV og andre retrovira

Info

Publication number
DK0817786T3
DK0817786T3 DK96911227T DK96911227T DK0817786T3 DK 0817786 T3 DK0817786 T3 DK 0817786T3 DK 96911227 T DK96911227 T DK 96911227T DK 96911227 T DK96911227 T DK 96911227T DK 0817786 T3 DK0817786 T3 DK 0817786T3
Authority
DK
Denmark
Prior art keywords
retroviruses
treatment
hiv
pct
acids useful
Prior art date
Application number
DK96911227T
Other languages
Danish (da)
English (en)
Inventor
Harvey Irving Skulnick
Paul Adrian Aristoff
Robert A Chrusciel
Suvit Thaisrivongs
W Jeffrey Howe
Linda Louise Maggiora
James Michael Tustin
Clark William Smith
Ruben Tommasi
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Application granted granted Critical
Publication of DK0817786T3 publication Critical patent/DK0817786T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/60—Two oxygen atoms, e.g. succinic anhydride
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/94—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom spiro-condensed with carbocyclic rings or ring systems, e.g. griseofulvins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK96911227T 1995-03-20 1996-03-07 Substituerede tetronsyrer, der er nyttige til behandling af HIV og andre retrovira DK0817786T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US40732295A 1995-03-20 1995-03-20
PCT/US1996/002680 WO1996029333A1 (fr) 1995-03-20 1996-03-07 Acides tetroniques substitues utiles comme medicaments contre le vih et d'autres retrovirus

Publications (1)

Publication Number Publication Date
DK0817786T3 true DK0817786T3 (da) 2003-05-26

Family

ID=23611540

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96911227T DK0817786T3 (da) 1995-03-20 1996-03-07 Substituerede tetronsyrer, der er nyttige til behandling af HIV og andre retrovira

Country Status (11)

Country Link
US (1) US6060600A (fr)
EP (1) EP0817786B1 (fr)
JP (1) JPH11503416A (fr)
AT (1) ATE232867T1 (fr)
AU (1) AU5417696A (fr)
DE (1) DE69626276T2 (fr)
DK (1) DK0817786T3 (fr)
ES (1) ES2191095T3 (fr)
PT (1) PT817786E (fr)
SI (1) SI0817786T1 (fr)
WO (1) WO1996029333A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9603097D0 (en) * 1996-02-14 1996-04-10 Zeneca Ltd Quinazoline compounds
JP3726684B2 (ja) * 2001-01-11 2005-12-14 株式会社Ｋｄｄｉ研究所 動画像データ転送における輻輳を回避する通信システム
DE102006039912A1 (de) * 2006-08-25 2008-03-20 Bayer Healthcare Ag Substituierte Spirotetronsäuren und ihre Verwendung
DE102006059319A1 (de) * 2006-12-15 2008-06-19 Bayer Healthcare Ag Substituierte Aminofuranone und ihre Verwendung

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA852614B (en) * 1985-05-17 1986-10-09 Takeda Chemical Industries, Ltd. Ascorbic acid ethers and their production
JP2515556B2 (ja) * 1986-08-29 1996-07-10 武田薬品工業株式会社 ヒドロキシブテノライド誘導体およびその製造法
DE68901024D1 (de) * 1988-10-20 1992-04-23 Shionogi & Co Gegen anaerobe bakterien wirksame antibiotika, ihre produktion und enterobakter-staemme, die sie produzieren.
JP3156006B2 (ja) * 1990-07-30 2001-04-16 武田薬品工業株式会社 テトロン酸誘導体、その製造法及び用途
EP0480624A1 (fr) * 1990-10-11 1992-04-15 Merck & Co. Inc. Inhibiteurs de HIV protease
WO1993004055A2 (fr) * 1991-08-27 1993-03-04 The Upjohn Company Composes utilises pour inhiber la vih protease
EP0534907B1 (fr) * 1991-09-26 1998-08-05 Nippon Zoki Pharmaceutical Co., Ltd. Utilisation de dérivées de furanone pour prevenir ou traiter des maladies d'autoimmunité
ZA938019B (en) * 1992-11-13 1995-04-28 Upjohn Co Pyran-2-ones and 5,6-dihydropyran-2-ones useful for treating HIV and other retroviruses
IL108459A0 (en) * 1993-02-05 1994-04-12 Opjohn Company 4-Hydroxy-benzopyran-2-ones and 4-hydroxy-cycloalkyl [B] pyran-2-ones useful for treating infections due to hiv and other retroviruses
JPH09502713A (ja) * 1993-09-17 1997-03-18 ジ・アップジョン・カンパニー Ｈｉｖおよび他のレトロウイルス病を治療するのに有用な置換テトロン酸

Also Published As

Publication number Publication date
US6060600A (en) 2000-05-09
SI0817786T1 (en) 2003-08-31
WO1996029333A1 (fr) 1996-09-26
ATE232867T1 (de) 2003-03-15
AU5417696A (en) 1996-10-08
ES2191095T3 (es) 2003-09-01
EP0817786A1 (fr) 1998-01-14
DE69626276D1 (de) 2003-03-27
JPH11503416A (ja) 1999-03-26
EP0817786B1 (fr) 2003-02-19
PT817786E (pt) 2003-06-30
DE69626276T2 (de) 2003-11-13

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