DK0816343T3 - Fremgangsmåde til fremstilling af chirale, ikke racemisk (4-aryl-2,5-dioxoimidazolidin-1-1-y)eddikesyrer - Google Patents

Fremgangsmåde til fremstilling af chirale, ikke racemisk (4-aryl-2,5-dioxoimidazolidin-1-1-y)eddikesyrer

Info

Publication number
DK0816343T3
DK0816343T3 DK97109739T DK97109739T DK0816343T3 DK 0816343 T3 DK0816343 T3 DK 0816343T3 DK 97109739 T DK97109739 T DK 97109739T DK 97109739 T DK97109739 T DK 97109739T DK 0816343 T3 DK0816343 T3 DK 0816343T3
Authority
DK
Denmark
Prior art keywords
racemic
chiral
preparation
dioxoimidazolidin
aryl
Prior art date
Application number
DK97109739T
Other languages
Danish (da)
English (en)
Inventor
Gerhard Dr Beck
Wolfgang Dr Holla
Bernhard Dr Kammermeier
Berndt Dl Kulitzscher
Juergen Michalowsky
Original Assignee
Sanofi Aventis Deutschland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis Deutschland filed Critical Sanofi Aventis Deutschland
Application granted granted Critical
Publication of DK0816343T3 publication Critical patent/DK0816343T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72—Two oxygen atoms, e.g. hydantoin
    • C07D233/76—Two oxygen atoms, e.g. hydantoin with substituted hydrocarbon radicals attached to the third ring carbon atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
DK97109739T 1996-06-20 1997-06-16 Fremgangsmåde til fremstilling af chirale, ikke racemisk (4-aryl-2,5-dioxoimidazolidin-1-1-y)eddikesyrer DK0816343T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19624604A DE19624604A1 (de) 1996-06-20 1996-06-20 Verfahren zur Herstellung chiraler, nicht racemischer (4-Aryl-2,5-dioxoimidazolidin-1-yl)essigsäuren

Publications (1)

Publication Number Publication Date
DK0816343T3 true DK0816343T3 (da) 2006-04-10

Family

ID=7797472

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97109739T DK0816343T3 (da) 1996-06-20 1997-06-16 Fremgangsmåde til fremstilling af chirale, ikke racemisk (4-aryl-2,5-dioxoimidazolidin-1-1-y)eddikesyrer

Country Status (11)

Country Link
US (1) US6018053A (ja)
EP (1) EP0816343B1 (ja)
JP (1) JP4199318B2 (ja)
KR (1) KR980002030A (ja)
AT (1) ATE312824T1 (ja)
AU (1) AU724816B2 (ja)
CA (1) CA2208129C (ja)
DE (2) DE19624604A1 (ja)
DK (1) DK0816343T3 (ja)
ES (1) ES2253761T3 (ja)
HU (1) HUP9701071A3 (ja)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005090316A1 (en) * 2004-03-12 2005-09-29 Wyeth HYDANTOINS HAVING RNase MODULATORY ACTIVITY
WO2015029447A1 (ja) * 2013-08-30 2015-03-05 興和株式会社 光学活性カルビノール化合物の製造方法
WO2015037243A1 (ja) * 2013-09-12 2015-03-19 興和株式会社 光学活性ヒダントイン化合物の製造方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2829157A (en) * 1953-03-10 1958-04-01 Leonard L Mckinney Novel hydantoic acids and their alkyl esters
US3939175A (en) * 1973-05-07 1976-02-17 Ciba-Geigy Corporation Hydroxyphenylated hydantoins
IT1164319B (it) * 1983-07-27 1987-04-08 Blaschim Spa Procedimento per la risoluzione dell'acido (+-)2-(6'-metossi-2'-naftil)-propionico
IT1196334B (it) * 1984-11-22 1988-11-16 Alfa Chem Ital Processo per la risoluzione ottica di miscugli racemi di acidi alfanaftil-propionici
NL9001703A (nl) * 1990-07-27 1992-02-17 Westspur Investment Ltd Werkwijze voor de bereiding van s(+)-6-methoxy-alfa-methyl-2-naftaleen-azijnzuur.
US5411981A (en) * 1991-01-09 1995-05-02 Roussel Uclaf Phenylimidazolidines having antiandrogenic activity
CA2074932A1 (en) * 1991-08-23 1993-02-24 Hiroyuki Nohira Optical resolution of (+)-2-(4-isobutylphenyl) propionic acid
AT398199B (de) * 1992-11-27 1994-10-25 Chemie Linz Gmbh Verfahren zur herstellung von arylhydantoinen
DE4427979A1 (de) * 1993-11-15 1996-02-15 Cassella Ag Substituierte 5-Ring-Heterocyclen, ihre Herstellung und ihre Verwendung
DE19515177A1 (de) * 1995-04-28 1996-10-31 Cassella Ag Hydantoinderivate als Zwischenprodukte für pharmazeutische Wirkstoffe

Also Published As

Publication number Publication date
EP0816343B1 (de) 2005-12-14
HUP9701071A3 (en) 1999-08-30
CA2208129A1 (en) 1997-12-20
EP0816343A1 (de) 1998-01-07
ES2253761T3 (es) 2006-06-01
KR980002030A (ko) 1998-03-30
US6018053A (en) 2000-01-25
ATE312824T1 (de) 2005-12-15
DE19624604A1 (de) 1998-01-02
HU9701071D0 (en) 1997-08-28
JP4199318B2 (ja) 2008-12-17
HUP9701071A2 (hu) 1998-04-28
CA2208129C (en) 2007-01-02
DE59712519D1 (de) 2006-01-19
JPH1059947A (ja) 1998-03-03
AU724816B2 (en) 2000-09-28
AU2613597A (en) 1998-01-08

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