DK0799030T3 - Pulverformuleringer indeholdende melezitose som fortyndingsmiddel - Google Patents

Pulverformuleringer indeholdende melezitose som fortyndingsmiddel

Info

Publication number
DK0799030T3
DK0799030T3 DK95942342T DK95942342T DK0799030T3 DK 0799030 T3 DK0799030 T3 DK 0799030T3 DK 95942342 T DK95942342 T DK 95942342T DK 95942342 T DK95942342 T DK 95942342T DK 0799030 T3 DK0799030 T3 DK 0799030T3
Authority
DK
Denmark
Prior art keywords
diluent
formulations containing
powder formulations
containing melezitose
melezitose
Prior art date
Application number
DK95942342T
Other languages
Danish (da)
English (en)
Inventor
Kjell Baeckstroem
Ann Johansson
Helena Linden
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of DK0799030T3 publication Critical patent/DK0799030T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Endocrinology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Toxicology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
DK95942342T 1994-12-22 1995-12-19 Pulverformuleringer indeholdende melezitose som fortyndingsmiddel DK0799030T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9404468A SE9404468D0 (sv) 1994-12-22 1994-12-22 Powder formulations
PCT/SE1995/001541 WO1996019207A1 (en) 1994-12-22 1995-12-19 Powder formulations containing melezitose as a diluent

Publications (1)

Publication Number Publication Date
DK0799030T3 true DK0799030T3 (da) 2002-09-16

Family

ID=20396435

Family Applications (2)

Application Number Title Priority Date Filing Date
DK01130870T DK1224929T3 (da) 1994-12-22 1995-12-19 Pulverformuleringer indeholdende melezitose som et fortyndingsmiddel
DK95942342T DK0799030T3 (da) 1994-12-22 1995-12-19 Pulverformuleringer indeholdende melezitose som fortyndingsmiddel

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK01130870T DK1224929T3 (da) 1994-12-22 1995-12-19 Pulverformuleringer indeholdende melezitose som et fortyndingsmiddel

Country Status (34)

Country Link
US (1) US6004574A (zh)
EP (2) EP0799030B1 (zh)
JP (1) JPH10510828A (zh)
KR (1) KR100391873B1 (zh)
CN (1) CN1080114C (zh)
AR (1) AR002261A1 (zh)
AT (2) ATE220900T1 (zh)
AU (1) AU702898B2 (zh)
BR (1) BR9510422A (zh)
CA (1) CA2206803A1 (zh)
CZ (1) CZ288487B6 (zh)
DE (2) DE69533294T2 (zh)
DK (2) DK1224929T3 (zh)
EE (1) EE03381B1 (zh)
ES (2) ES2222306T3 (zh)
FI (1) FI972654A (zh)
HK (1) HK1003619A1 (zh)
HU (1) HU217975B (zh)
IL (1) IL116459A (zh)
IS (1) IS1848B (zh)
MY (1) MY114211A (zh)
NO (1) NO315966B1 (zh)
NZ (1) NZ298168A (zh)
PL (1) PL183944B1 (zh)
PT (2) PT1224929E (zh)
RU (1) RU2144819C1 (zh)
SA (1) SA95160484B1 (zh)
SE (1) SE9404468D0 (zh)
SK (1) SK283147B6 (zh)
TR (1) TR199501632A1 (zh)
TW (1) TW474823B (zh)
UA (1) UA44757C2 (zh)
WO (1) WO1996019207A1 (zh)
ZA (1) ZA9510753B (zh)

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US6524557B1 (en) * 1994-12-22 2003-02-25 Astrazeneca Ab Aerosol formulations of peptides and proteins
PL320856A1 (en) * 1994-12-22 1997-11-10 Astra Ab Aerosol drug preparations
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US6713452B2 (en) 2001-06-04 2004-03-30 Nobex Corporation Mixtures of calcitonin drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same
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US7713932B2 (en) 2001-06-04 2010-05-11 Biocon Limited Calcitonin drug-oligomer conjugates, and uses thereof
US6770625B2 (en) 2001-09-07 2004-08-03 Nobex Corporation Pharmaceutical compositions of calcitonin drug-oligomer conjugates and methods of treating diseases therewith
US7030082B2 (en) * 2001-09-07 2006-04-18 Nobex Corporation Pharmaceutical compositions of drug-oligomer conjugates and methods of treating disease therewith
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SE0200657D0 (sv) * 2002-03-04 2002-03-04 Astrazeneca Ab Novel Formulation
WO2006014673A2 (en) 2004-07-19 2006-02-09 Nobex Corporation Insulin-oligomer conjugates, formulations and uses thereof
US9895444B2 (en) 2004-08-25 2018-02-20 Aegis Therapeutics, Llc Compositions for drug administration
US20090047347A1 (en) * 2005-07-29 2009-02-19 Aegis Therapeutics, Inc. Compositions for Drug Administration
US20060046962A1 (en) 2004-08-25 2006-03-02 Aegis Therapeutics Llc Absorption enhancers for drug administration
US20140162965A1 (en) 2004-08-25 2014-06-12 Aegis Therapeutics, Inc. Compositions for oral drug administration
WO2006025882A2 (en) * 2004-08-25 2006-03-09 The Uab Research Foundation Absorption enhancers for drug administration
US8268791B2 (en) * 2004-08-25 2012-09-18 Aegis Therapeutics, Llc. Alkylglycoside compositions for drug administration
US8226949B2 (en) 2006-06-23 2012-07-24 Aegis Therapeutics Llc Stabilizing alkylglycoside compositions and methods thereof
PL2203181T3 (pl) 2007-10-16 2018-07-31 Biocon Limited Podawana doustnie stała kompozycja farmaceutyczna i jej sposób
ES2586032T3 (es) 2008-03-28 2016-10-11 Hale Biopharma Ventures, Llc Administración de composiciones de benzodiazepinas
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US8440631B2 (en) * 2008-12-22 2013-05-14 Aegis Therapeutics, Llc Compositions for drug administration
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Also Published As

Publication number Publication date
IL116459A (en) 2002-11-10
NZ298168A (en) 1999-08-30
PL320751A1 (en) 1997-10-27
BR9510422A (pt) 1998-07-07
CZ194697A3 (en) 1997-10-15
MY114211A (en) 2002-08-30
EE03381B1 (et) 2001-04-16
DE69527542D1 (de) 2002-08-29
TR199501632A1 (tr) 1997-03-21
MX9704551A (es) 1997-10-31
PL183944B1 (pl) 2002-08-30
CZ288487B6 (en) 2001-06-13
UA44757C2 (uk) 2002-03-15
PT1224929E (pt) 2004-10-29
FI972654A0 (fi) 1997-06-19
HUT77648A (hu) 1998-07-28
KR100391873B1 (ko) 2003-10-17
HK1003619A1 (en) 1998-11-06
IL116459A0 (en) 1996-03-31
EP0799030B1 (en) 2002-07-24
SE9404468D0 (sv) 1994-12-22
SK283147B6 (sk) 2003-03-04
NO972660D0 (no) 1997-06-10
ES2222306T3 (es) 2005-02-01
EE9700135A (et) 1997-12-15
US6004574A (en) 1999-12-21
NO972660L (no) 1997-06-10
TW474823B (en) 2002-02-01
CN1080114C (zh) 2002-03-06
AU4359296A (en) 1996-07-10
HU217975B (hu) 2000-05-28
WO1996019207A1 (en) 1996-06-27
CA2206803A1 (en) 1996-06-27
SK81297A3 (en) 1997-11-05
ZA9510753B (en) 1996-06-24
NO315966B1 (no) 2003-11-24
JPH10510828A (ja) 1998-10-20
RU2144819C1 (ru) 2000-01-27
DE69527542T2 (de) 2003-01-30
EP1224929A2 (en) 2002-07-24
SA95160484B1 (ar) 2005-10-01
ES2177674T3 (es) 2002-12-16
EP1224929A3 (en) 2002-12-18
EP1224929B1 (en) 2004-07-21
IS4495A (is) 1997-06-03
EP0799030A1 (en) 1997-10-08
FI972654A (fi) 1997-06-19
DK1224929T3 (da) 2004-10-04
PT799030E (pt) 2002-11-29
ATE220900T1 (de) 2002-08-15
IS1848B (is) 2003-02-07
CN1171049A (zh) 1998-01-21
ATE271382T1 (de) 2004-08-15
DE69533294T2 (de) 2005-05-19
AU702898B2 (en) 1999-03-11
AR002261A1 (es) 1998-03-11
DE69533294D1 (de) 2004-08-26

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