DK0793714T3 - Anvendelse af stamcellefaktor og opløselig interleukin-6-receptor til ex vivo ekspansion af hæmatopoietiske multipotentielle celler - Google Patents

Anvendelse af stamcellefaktor og opløselig interleukin-6-receptor til ex vivo ekspansion af hæmatopoietiske multipotentielle celler

Info

Publication number
DK0793714T3
DK0793714T3 DK95942865T DK95942865T DK0793714T3 DK 0793714 T3 DK0793714 T3 DK 0793714T3 DK 95942865 T DK95942865 T DK 95942865T DK 95942865 T DK95942865 T DK 95942865T DK 0793714 T3 DK0793714 T3 DK 0793714T3
Authority
DK
Denmark
Prior art keywords
receptor
stem cell
cell factor
hematopoietic
soluble interleukin
Prior art date
Application number
DK95942865T
Other languages
Danish (da)
English (en)
Inventor
Tatsutoshi Nakahata
Original Assignee
Tosoh Corp
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/340,559 external-priority patent/US5610056A/en
Application filed by Tosoh Corp, Amgen Inc filed Critical Tosoh Corp
Application granted granted Critical
Publication of DK0793714T3 publication Critical patent/DK0793714T3/da

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0634Cells from the blood or the immune system
    • C12N5/0641Erythrocytes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0634Cells from the blood or the immune system
    • C12N5/0647Haematopoietic stem cells; Uncommitted or multipotent progenitors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/05Inorganic components
    • C12N2500/10Metals; Metal chelators
    • C12N2500/20Transition metals
    • C12N2500/24Iron; Fe chelators; Transferrin
    • C12N2500/25Insulin-transferrin; Insulin-transferrin-selenium
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/30Organic components
    • C12N2500/36Lipids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/90Serum-free medium, which may still contain naturally-sourced components
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10Growth factors
    • C12N2501/125Stem cell factor [SCF], c-kit ligand [KL]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20Cytokines; Chemokines
    • C12N2501/23Interleukins [IL]

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK95942865T 1994-11-16 1995-11-16 Anvendelse af stamcellefaktor og opløselig interleukin-6-receptor til ex vivo ekspansion af hæmatopoietiske multipotentielle celler DK0793714T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/340,559 US5610056A (en) 1994-11-16 1994-11-16 Use of stem cell factor interleukin-6 and soluble interleukin-6 receptor to induce the development of hematopoietic stem cells
US39314695A 1995-02-21 1995-02-21
PCT/US1995/014999 WO1996015230A2 (fr) 1994-11-16 1995-11-16 Utilisation du facteur des cellules souches et du recepteur de l'interleukine 6 soluble dans le developpement ex vivo des cellules multipotentielles hematopoietiques

Publications (1)

Publication Number Publication Date
DK0793714T3 true DK0793714T3 (da) 2002-09-02

Family

ID=26992162

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95942865T DK0793714T3 (da) 1994-11-16 1995-11-16 Anvendelse af stamcellefaktor og opløselig interleukin-6-receptor til ex vivo ekspansion af hæmatopoietiske multipotentielle celler

Country Status (13)

Country Link
US (1) US5861315A (fr)
EP (1) EP0793714B1 (fr)
JP (1) JP3600244B2 (fr)
CN (1) CN1170926C (fr)
AT (1) ATE221118T1 (fr)
AU (1) AU699479B2 (fr)
CA (1) CA2198603C (fr)
DE (1) DE69527540T2 (fr)
DK (1) DK0793714T3 (fr)
ES (1) ES2180665T3 (fr)
MX (1) MX9701512A (fr)
PT (1) PT793714E (fr)
WO (1) WO1996015230A2 (fr)

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CA2476553A1 (fr) * 2002-02-13 2003-08-21 Anthrogenesis Corporation Cellules souches de type embryonnaire derivees de placenta mammalien post-partum, utilisations, et procedes de traitement a base de cellules de ce type
US7682803B2 (en) 2005-10-13 2010-03-23 Anthrogenesis Corporation Immunomodulation using placental stem cells
US20040076617A1 (en) * 2002-03-18 2004-04-22 Lieber Jonathan Gregory Method for production of neutrophils and uses therefor
CA2483010A1 (fr) * 2002-04-19 2003-10-30 University Of Pittsburgh Of The Commonwealth System Of Higher Education Cellules souches placentaires et utilisations
US20040161419A1 (en) * 2002-04-19 2004-08-19 Strom Stephen C. Placental stem cells and uses thereof
US20040042997A1 (en) * 2002-09-03 2004-03-04 Donnie Rudd Method of regenerating human tissue
US20040076620A1 (en) * 2002-09-03 2004-04-22 Donnie Rudd Method of repairing primate mammalian tissue
US20040044300A1 (en) * 2002-09-03 2004-03-04 Donnie Rudd Method of replenishing cells damaged by treatment for cancer
US20040076605A1 (en) * 2002-09-03 2004-04-22 Donnie Rudd Method of regenerating human tissue
US20040043009A1 (en) * 2002-09-03 2004-03-04 Donnie Rudd Method of repairing primate mammalian tissue
US20040077985A1 (en) * 2002-09-03 2004-04-22 Donnie Rudd Method of replenishing cells damaged by treatment for cancer
EP1400587A1 (fr) * 2002-09-19 2004-03-24 MainGen Biotechnologie GmbH Utilisation de polypeptide de fusion pour l'obtention de cellules souches pluripontentes non embryonales
AU2003295444A1 (en) * 2002-11-15 2004-06-15 The Board Of Trustees Of The University Of Illinois Methods for in vitro expansion of hematopoietic stem cells
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EP1601248A4 (fr) * 2003-02-13 2010-01-27 Anthrogenesis Corp Utilisation de sang de cordon ombilical pour traiter des individus presentant une maladie, un trouble ou une pathologie
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EP1694328A4 (fr) * 2003-12-02 2010-02-17 Celgene Corp Procedes et compositions de traitement et de gestion de l'hemoglobinopathie et de l'anemie
WO2006019357A1 (fr) 2004-08-16 2006-02-23 Cellresearch Corporation Pte Ltd Isolement de cellules souches/progenitrices issues de la membrane amniotique du cordon ombilical
WO2006093857A2 (fr) * 2005-02-28 2006-09-08 Regenetech, Inc. Procede de production d'une substance cellulaire facilement disponible derivee du sang peripherique et composition de cette substance
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EP2607477B1 (fr) * 2007-05-03 2020-09-23 The Brigham and Women's Hospital, Inc. Cellules souches multipotentes et leurs utilisations
US8574567B2 (en) * 2007-05-03 2013-11-05 The Brigham And Women's Hospital, Inc. Multipotent stem cells and uses thereof
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KR20220098055A (ko) * 2007-11-07 2022-07-08 셀룰래리티 인코포레이티드 조산 합병증의 치료에 있어서의 제대혈의 용도
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Also Published As

Publication number Publication date
EP0793714A2 (fr) 1997-09-10
WO1996015230A3 (fr) 1996-07-11
ES2180665T3 (es) 2003-02-16
JP3600244B2 (ja) 2004-12-15
US5861315A (en) 1999-01-19
AU4407396A (en) 1996-06-06
CN1224461A (zh) 1999-07-28
DE69527540D1 (de) 2002-08-29
MX9701512A (es) 1997-05-31
AU699479B2 (en) 1998-12-03
ATE221118T1 (de) 2002-08-15
DE69527540T2 (de) 2003-01-30
CA2198603A1 (fr) 1996-05-23
PT793714E (pt) 2002-12-31
EP0793714B1 (fr) 2002-07-24
CA2198603C (fr) 2000-06-27
CN1170926C (zh) 2004-10-13
JPH10509040A (ja) 1998-09-08
WO1996015230A2 (fr) 1996-05-23

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