DK0784486T3 - Interleukin-12 som en adjuvans til Paramyxoviridae-vacciner - Google Patents

Interleukin-12 som en adjuvans til Paramyxoviridae-vacciner

Info

Publication number
DK0784486T3
DK0784486T3 DK95938133T DK95938133T DK0784486T3 DK 0784486 T3 DK0784486 T3 DK 0784486T3 DK 95938133 T DK95938133 T DK 95938133T DK 95938133 T DK95938133 T DK 95938133T DK 0784486 T3 DK0784486 T3 DK 0784486T3
Authority
DK
Denmark
Prior art keywords
virus
interleukin
paramyxoviridae family
parainfluenza
paramyxoviridae
Prior art date
Application number
DK95938133T
Other languages
Danish (da)
English (en)
Inventor
Barney S Graham
Yi-Wei Tang
Original Assignee
Univ Vanderbilt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Vanderbilt filed Critical Univ Vanderbilt
Application granted granted Critical
Publication of DK0784486T3 publication Critical patent/DK0784486T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1027—Paramyxoviridae, e.g. respiratory syncytial virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/155—Paramyxoviridae, e.g. parainfluenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5252—Virus inactivated (killed)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55522—Cytokines; Lymphokines; Interferons
    • A61K2039/55527—Interleukins
    • A61K2039/55538—IL-12
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
    • C12N2760/18534—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Organic Chemistry (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
DK95938133T 1994-10-05 1995-10-02 Interleukin-12 som en adjuvans til Paramyxoviridae-vacciner DK0784486T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US31848094A 1994-10-05 1994-10-05

Publications (1)

Publication Number Publication Date
DK0784486T3 true DK0784486T3 (da) 2006-08-14

Family

ID=23238354

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95938133T DK0784486T3 (da) 1994-10-05 1995-10-02 Interleukin-12 som en adjuvans til Paramyxoviridae-vacciner

Country Status (11)

Country Link
US (2) US6071893A (de)
EP (1) EP0784486B1 (de)
JP (1) JP3939752B2 (de)
AT (1) ATE322289T1 (de)
AU (1) AU701753B2 (de)
DE (1) DE69534922T2 (de)
DK (1) DK0784486T3 (de)
ES (1) ES2257744T3 (de)
MX (1) MX9702396A (de)
PT (1) PT784486E (de)
WO (1) WO1996011019A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3737519B2 (ja) * 1996-05-31 2006-01-18 ジェネティックス・インスチチュート・リミテッド・ライアビリティ・カンパニー 百日咳菌ワクチン用アジュバントとしてのｉｌ―１２
GB9712347D0 (en) 1997-06-14 1997-08-13 Smithkline Beecham Biolog Vaccine
AU759391B2 (en) * 1998-02-12 2003-04-10 Wyeth Holdings Corporation Pneumococcal and meningococcal vaccines formulated with interleukin-12
EP1053016A2 (de) * 1998-02-12 2000-11-22 American Cyanamid Company Interleukin-12 und respiratory-syncytial-virusantigene enthaltende impfstoffe
US6814968B1 (en) 1998-06-04 2004-11-09 Vanderbilt University Inhibition of viral infection and spread with viral and RhoA-derived peptides
WO2000069456A2 (en) * 1999-05-13 2000-11-23 American Cyanamid Company Adjuvant combination formulations
US7374751B1 (en) 2000-06-22 2008-05-20 Wyeth Holdings Corporation QS-21 and IL-12 as an adjuvant combination
HUP0600589A2 (en) * 2000-11-10 2006-11-28 Wyeth Corp Adjuvant combination formulations
US20030129161A1 (en) * 2001-09-17 2003-07-10 Hsien-Jue Chu Interleukin-12 as a veterinary vaccine adjuvant
US20090227025A1 (en) * 2003-06-06 2009-09-10 The Board Of Regents Of The University Of Texas System Ex vivo human lung/immune system model using tissue engineering for studying microbial pathogens with lung tropism
CN113304158B (zh) * 2021-06-10 2022-10-28 山东省农业科学院畜牧兽医研究所 磺胺甲氧吡嗪在制备预防和/或治疗牛副流感病毒产品中的应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5223254A (en) * 1987-09-29 1993-06-29 Praxis Biologics, Inc. Respiratory syncytial virus: vaccines
GB8914968D0 (en) * 1989-06-29 1989-08-23 Connaught Lab Production of virus and purification of viral envelope proteins for vaccine use
TW275632B (de) * 1992-04-21 1996-05-11 American Cyanamid Co
EP0604727A1 (de) * 1992-12-31 1994-07-06 American Cyanamid Company Verbesserte Immunogenizität einer Vakzine durch Inkorporieren eines Zytokines in einen immun-stimulierenden Komplex, der ein Antigen enthält
ATE196737T1 (de) * 1993-05-25 2000-10-15 American Cyanamid Co Adjuvantien für impfstoffe gegen das respiratorische synzitialvirus
US5830463A (en) * 1993-07-07 1998-11-03 University Technology Corporation Yeast-based delivery vehicles
US7223410B1 (en) * 1994-08-05 2007-05-29 Sanofi Pasteur Limited Inactivated respiratory syncytial viral vaccines
US5571515A (en) * 1994-04-18 1996-11-05 The Wistar Institute Of Anatomy & Biology Compositions and methods for use of IL-12 as an adjuvant
ZA953703B (en) * 1994-05-10 1996-01-10 American Home Prod Modified live BRSV vaccine

Also Published As

Publication number Publication date
AU3887695A (en) 1996-05-02
DE69534922T2 (de) 2006-11-23
PT784486E (pt) 2006-07-31
MX9702396A (es) 1997-12-31
ATE322289T1 (de) 2006-04-15
US6071893A (en) 2000-06-06
ES2257744T3 (es) 2006-08-01
JP3939752B2 (ja) 2007-07-04
EP0784486A1 (de) 1997-07-23
EP0784486B1 (de) 2006-04-05
US20070087016A1 (en) 2007-04-19
DE69534922D1 (en) 2006-05-18
AU701753B2 (en) 1999-02-04
JPH10507175A (ja) 1998-07-14
WO1996011019A1 (en) 1996-04-18

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