DK0779271T3 - Naphthylacetamider som sPLA2-inhibitorer - Google Patents
Naphthylacetamider som sPLA2-inhibitorerInfo
- Publication number
- DK0779271T3 DK0779271T3 DK96308915T DK96308915T DK0779271T3 DK 0779271 T3 DK0779271 T3 DK 0779271T3 DK 96308915 T DK96308915 T DK 96308915T DK 96308915 T DK96308915 T DK 96308915T DK 0779271 T3 DK0779271 T3 DK 0779271T3
- Authority
- DK
- Denmark
- Prior art keywords
- spla2 inhibitors
- acetamides
- naphthyl
- compounds
- naphthyl acetamides
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C235/34—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
- C07C229/08—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to hydrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/02—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
- C07C233/11—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to carbon atoms of an unsaturated carbon skeleton containing six-membered aromatic rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Otolaryngology (AREA)
- Epidemiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Indole Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US855895P | 1995-12-13 | 1995-12-13 | |
| GBGB9602267.8A GB9602267D0 (en) | 1996-02-05 | 1996-02-05 | Naphthyl acetamides as sPLA2 inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0779271T3 true DK0779271T3 (da) | 2001-10-08 |
Family
ID=26308607
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK96308915T DK0779271T3 (da) | 1995-12-13 | 1996-12-09 | Naphthylacetamider som sPLA2-inhibitorer |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US6160175A (pt) |
| EP (1) | EP0779271B1 (pt) |
| JP (1) | JP2000501739A (pt) |
| KR (1) | KR19990072110A (pt) |
| AT (1) | ATE203744T1 (pt) |
| AU (1) | AU1289797A (pt) |
| BR (1) | BR9612347A (pt) |
| CA (1) | CA2240395A1 (pt) |
| DE (1) | DE69614232T2 (pt) |
| DK (1) | DK0779271T3 (pt) |
| ES (1) | ES2159347T3 (pt) |
| GR (1) | GR3036988T3 (pt) |
| HU (1) | HUP9901984A3 (pt) |
| IL (1) | IL124866A (pt) |
| MX (1) | MX9804751A (pt) |
| PT (1) | PT779271E (pt) |
| WO (1) | WO1997021664A1 (pt) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6713645B1 (en) * | 1996-10-30 | 2004-03-30 | Eli Lilly And Company | Substituted tricyclics |
| US6177440B1 (en) | 1996-10-30 | 2001-01-23 | Eli Lilly And Company | Substituted tricyclics |
| US6353128B1 (en) * | 1996-12-03 | 2002-03-05 | Eli Lilly And Company | Phenyl acetamides as sPLA2 inhibitors |
| US5916922A (en) * | 1996-12-03 | 1999-06-29 | Eli Lilly And Company | Phenyl glyoxamides as SPLA2 inhibitors |
| EP1066290A1 (en) | 1998-03-31 | 2001-01-10 | Shionogi & Co., Ltd. | PYRROLO[1,2-a]PYRAZINE sPLA 2 INHIBITOR |
| DZ2769A1 (fr) * | 1998-04-17 | 2003-12-01 | Lilly Co Eli | Composés tricycliques substitués. |
| ID23219A (id) * | 1998-04-17 | 2000-03-30 | Lilly Co Eli | Trisiklik tersubstitusi |
| EP1085021A4 (en) | 1998-05-21 | 2003-01-08 | Shionogi & Co | DERIVATIVES OF PYRROLO 1,2-B] PYRIDAZINE, WITH INHIBITOR EFFECT ON SPLA 2? |
| DE69931963D1 (de) * | 1998-10-14 | 2006-07-27 | Shionogi & Co | Spla2-inhibitoren zur behandlung von ischämischen reperfusionsschäden |
| US6703385B1 (en) | 1999-07-19 | 2004-03-09 | Shionogi & Co., Ltd. | Tricyclic compounds having sPLA2-inhibitory activities |
| US6673781B1 (en) | 1999-08-02 | 2004-01-06 | Shionogi & Co., Ltd. | Tricyclic compounds having sPLA2-inhibitory activities |
| WO2001014378A1 (fr) | 1999-08-23 | 2001-03-01 | Shionogi & Co., Ltd. | DERIVES DE PYRROLOTRIAZINE A ACTIVITES INHIBANT sPLA¿2? |
| WO2001036420A1 (fr) | 1999-11-15 | 2001-05-25 | Shionogi & Co., Ltd. | Derives d'aza-indolizine tricyclique ayant un effet inhibiteur sur spla¿2? |
| AU2001267823A1 (en) | 2000-06-29 | 2002-01-08 | Shionogi And Co., Ltd. | Compounds exhibiting x-type spla2 inhibiting effect |
| US6967200B2 (en) | 2000-06-29 | 2005-11-22 | Shionogi & Co., Ltd. | Remedies for cirrhosis |
| TWI314457B (pt) | 2001-03-19 | 2009-09-11 | Shionogi & Co | |
| US20060064279A1 (en) * | 2004-09-17 | 2006-03-23 | Eric Baum | Algorithm for retrieval of ocean surface temperature, wind speed and wind direction from remote microwave radiometric measurements |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3820463A1 (de) * | 1988-06-16 | 1989-12-21 | Basf Ag | Strahlungsempfindliche, ethylenisch ungesaettigte, copolymerisierbare verbindungen und verfahren zu deren herstellung |
| FR2658818B1 (fr) * | 1990-02-27 | 1993-12-31 | Adir Cie | Nouveaux derives a structure naphtalenique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
-
1996
- 1996-12-09 CA CA002240395A patent/CA2240395A1/en not_active Abandoned
- 1996-12-09 WO PCT/US1996/019874 patent/WO1997021664A1/en not_active Application Discontinuation
- 1996-12-09 AT AT96308915T patent/ATE203744T1/de not_active IP Right Cessation
- 1996-12-09 US US09/091,077 patent/US6160175A/en not_active Expired - Fee Related
- 1996-12-09 PT PT96308915T patent/PT779271E/pt unknown
- 1996-12-09 EP EP96308915A patent/EP0779271B1/en not_active Expired - Lifetime
- 1996-12-09 AU AU12897/97A patent/AU1289797A/en not_active Abandoned
- 1996-12-09 DE DE69614232T patent/DE69614232T2/de not_active Expired - Fee Related
- 1996-12-09 ES ES96308915T patent/ES2159347T3/es not_active Expired - Lifetime
- 1996-12-09 DK DK96308915T patent/DK0779271T3/da active
- 1996-12-09 KR KR1019980704425A patent/KR19990072110A/ko not_active Application Discontinuation
- 1996-12-09 IL IL12486696A patent/IL124866A/en not_active IP Right Cessation
- 1996-12-09 HU HU9901984A patent/HUP9901984A3/hu unknown
- 1996-12-09 JP JP9522227A patent/JP2000501739A/ja not_active Ceased
- 1996-12-09 BR BR9612347A patent/BR9612347A/pt not_active Application Discontinuation
-
1998
- 1998-06-12 MX MX9804751A patent/MX9804751A/es not_active IP Right Cessation
-
2001
- 2001-10-24 GR GR20010401861T patent/GR3036988T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| IL124866A0 (en) | 1999-01-26 |
| US6160175A (en) | 2000-12-12 |
| EP0779271A1 (en) | 1997-06-18 |
| AU1289797A (en) | 1997-07-03 |
| PT779271E (pt) | 2001-11-30 |
| BR9612347A (pt) | 1999-07-13 |
| DE69614232T2 (de) | 2002-01-10 |
| KR19990072110A (ko) | 1999-09-27 |
| CA2240395A1 (en) | 1997-06-19 |
| EP0779271B1 (en) | 2001-08-01 |
| ATE203744T1 (de) | 2001-08-15 |
| DE69614232D1 (de) | 2001-09-06 |
| GR3036988T3 (en) | 2002-01-31 |
| HUP9901984A3 (en) | 2001-01-29 |
| WO1997021664A1 (en) | 1997-06-19 |
| ES2159347T3 (es) | 2001-10-01 |
| MX9804751A (es) | 1998-10-31 |
| IL124866A (en) | 2002-08-14 |
| HUP9901984A2 (hu) | 1999-10-28 |
| JP2000501739A (ja) | 2000-02-15 |
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| DK0779271T3 (da) | Naphthylacetamider som sPLA2-inhibitorer | |
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