DK0759030T3 - N-[N-(3,3-dimethylbutyl)-L-alfa-aspartyl]-L-hexahydrophenylalanin-1-methylester, som er anvendelig som sødemiddel, samt en - Google Patents
N-[N-(3,3-dimethylbutyl)-L-alfa-aspartyl]-L-hexahydrophenylalanin-1-methylester, som er anvendelig som sødemiddel, samt enInfo
- Publication number
- DK0759030T3 DK0759030T3 DK95919483T DK95919483T DK0759030T3 DK 0759030 T3 DK0759030 T3 DK 0759030T3 DK 95919483 T DK95919483 T DK 95919483T DK 95919483 T DK95919483 T DK 95919483T DK 0759030 T3 DK0759030 T3 DK 0759030T3
- Authority
- DK
- Denmark
- Prior art keywords
- pct
- hexahydrophenylalanine
- aspartyl
- dimethylbutyl
- alpha
- Prior art date
Links
- -1 3,3-dimethylbutyl Chemical group 0.000 title 1
- 235000003599 food sweetener Nutrition 0.000 title 1
- 239000003765 sweetening agent Substances 0.000 title 1
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 abstract 3
- 235000010357 aspartame Nutrition 0.000 abstract 2
- FGOJCPKOOGIRPA-UHFFFAOYSA-N 1-o-tert-butyl 4-o-ethyl 5-oxoazepane-1,4-dicarboxylate Chemical compound CCOC(=O)C1CCN(C(=O)OC(C)(C)C)CCC1=O FGOJCPKOOGIRPA-UHFFFAOYSA-N 0.000 abstract 1
- LTNUSYNQZJZUSY-UHFFFAOYSA-N 3,3-dimethylbutanal Chemical compound CC(C)(C)CC=O LTNUSYNQZJZUSY-UHFFFAOYSA-N 0.000 abstract 1
- 108010011485 Aspartame Proteins 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000003158 alcohol group Chemical group 0.000 abstract 1
- IAOZJIPTCAWIRG-QWRGUYRKSA-N aspartame Chemical compound OC(=O)C[C@H](N)C(=O)N[C@H](C(=O)OC)CC1=CC=CC=C1 IAOZJIPTCAWIRG-QWRGUYRKSA-N 0.000 abstract 1
- 239000000605 aspartame Substances 0.000 abstract 1
- 229960003438 aspartame Drugs 0.000 abstract 1
- 239000003054 catalyst Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000001704 evaporation Methods 0.000 abstract 1
- 230000008020 evaporation Effects 0.000 abstract 1
- 238000001914 filtration Methods 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- MUMZUERVLWJKNR-UHFFFAOYSA-N oxoplatinum Chemical compound [Pt]=O MUMZUERVLWJKNR-UHFFFAOYSA-N 0.000 abstract 1
- 229910052697 platinum Inorganic materials 0.000 abstract 1
- 229910003446 platinum oxide Inorganic materials 0.000 abstract 1
- 238000001556 precipitation Methods 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06104—Dipeptides with the first amino acid being acidic
- C07K5/06113—Asp- or Asn-amino acid
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Life Sciences & Earth Sciences (AREA)
- Peptides Or Proteins (AREA)
- Seasonings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9405675A FR2719591B1 (fr) | 1994-05-09 | 1994-05-09 | Nouveau composé utile comme agent édulcorant, son procédé de préparation. |
| PCT/FR1995/000588 WO1995030688A1 (fr) | 1994-05-09 | 1995-05-05 | N-[N-(3,3-DIMETHYLBUTYL)-L-α-ASPARTYL]-L-HEXAHYDROPHENYLALANINE 1-METHYL ESTER UTILE COMME AGENT EDULCORANT, SON PROCEDE DE PREPARATION |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0759030T3 true DK0759030T3 (da) | 1999-06-07 |
Family
ID=9463025
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK95919483T DK0759030T3 (da) | 1994-05-09 | 1995-05-05 | N-[N-(3,3-dimethylbutyl)-L-alfa-aspartyl]-L-hexahydrophenylalanin-1-methylester, som er anvendelig som sødemiddel, samt en |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US5773640A (ja) |
| EP (1) | EP0759030B1 (ja) |
| JP (1) | JP3627062B2 (ja) |
| CN (1) | CN1147818A (ja) |
| AT (1) | ATE170872T1 (ja) |
| AU (1) | AU2528495A (ja) |
| BR (1) | BR9507628A (ja) |
| CA (1) | CA2189558A1 (ja) |
| DE (1) | DE69504651T2 (ja) |
| DK (1) | DK0759030T3 (ja) |
| ES (1) | ES2123984T3 (ja) |
| FR (1) | FR2719591B1 (ja) |
| HK (1) | HK1012407A1 (ja) |
| RU (1) | RU2138511C1 (ja) |
| WO (1) | WO1995030688A1 (ja) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH11169132A (ja) * | 1997-12-15 | 1999-06-29 | Ajinomoto Co Inc | アスパルテームとアスパルテーム誘導体の混晶及びその製造方法 |
| US6692778B2 (en) * | 1998-06-05 | 2004-02-17 | Wm. Wrigley Jr. Company | Method of controlling release of N-substituted derivatives of aspartame in chewing gum |
| KR100631306B1 (ko) * | 1998-06-26 | 2006-10-09 | 아지노모토 가부시키가이샤 | 아스파르틸 디펩타이드 에스테르 유도체 및 이를 함유하는 감미제 |
| US6844465B2 (en) | 1998-10-30 | 2005-01-18 | Ajinomoto Co., Inc. | Method for preparing highly stable crystals of aspartame derivative |
| WO2000026235A1 (fr) * | 1998-10-30 | 2000-05-11 | Ajinomoto Co., Inc. | Procede de preparation de cristaux de derive d'aspartame possedant une excellente stabilite |
| CN1317012A (zh) | 1998-10-30 | 2001-10-10 | 味之素株式会社 | 稳定性优良的天冬甜素衍生物晶体的结晶方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1258248A (ja) * | 1968-07-17 | 1971-12-22 | ||
| FR2719590B1 (fr) * | 1994-05-09 | 1996-07-26 | Claude Nofre | Procédé perfectionné de préparation d'un composé dérivé de l'aspartame utile comme agent édulcorant. |
-
1994
- 1994-05-09 FR FR9405675A patent/FR2719591B1/fr not_active Expired - Lifetime
-
1995
- 1995-05-05 CA CA002189558A patent/CA2189558A1/en not_active Abandoned
- 1995-05-05 EP EP95919483A patent/EP0759030B1/fr not_active Expired - Lifetime
- 1995-05-05 RU RU96123232A patent/RU2138511C1/ru active
- 1995-05-05 JP JP52872595A patent/JP3627062B2/ja not_active Expired - Fee Related
- 1995-05-05 BR BR9507628A patent/BR9507628A/pt not_active Application Discontinuation
- 1995-05-05 DE DE69504651T patent/DE69504651T2/de not_active Expired - Fee Related
- 1995-05-05 ES ES95919483T patent/ES2123984T3/es not_active Expired - Lifetime
- 1995-05-05 AU AU25284/95A patent/AU2528495A/en not_active Abandoned
- 1995-05-05 WO PCT/FR1995/000588 patent/WO1995030688A1/fr active IP Right Grant
- 1995-05-05 DK DK95919483T patent/DK0759030T3/da active
- 1995-05-05 AT AT95919483T patent/ATE170872T1/de not_active IP Right Cessation
- 1995-05-05 US US08/737,138 patent/US5773640A/en not_active Expired - Fee Related
- 1995-05-05 CN CN95192974A patent/CN1147818A/zh active Pending
-
1998
- 1998-12-16 HK HK98113670A patent/HK1012407A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| WO1995030688A1 (fr) | 1995-11-16 |
| EP0759030B1 (fr) | 1998-09-09 |
| EP0759030A1 (fr) | 1997-02-26 |
| CA2189558A1 (en) | 1995-11-16 |
| FR2719591A1 (fr) | 1995-11-10 |
| HK1012407A1 (en) | 1999-07-30 |
| AU2528495A (en) | 1995-11-29 |
| RU2138511C1 (ru) | 1999-09-27 |
| ES2123984T3 (es) | 1999-01-16 |
| US5773640A (en) | 1998-06-30 |
| JPH10500403A (ja) | 1998-01-13 |
| DE69504651D1 (de) | 1998-10-15 |
| BR9507628A (pt) | 1997-09-23 |
| FR2719591B1 (fr) | 1996-07-26 |
| JP3627062B2 (ja) | 2005-03-09 |
| CN1147818A (zh) | 1997-04-16 |
| DE69504651T2 (de) | 1999-04-08 |
| ATE170872T1 (de) | 1998-09-15 |
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