DK0755248T3 - Gelerede mikrosfærer, fremgangsmåde til deres fremstilling og deres anvendelser - Google Patents

Gelerede mikrosfærer, fremgangsmåde til deres fremstilling og deres anvendelser

Info

Publication number
DK0755248T3
DK0755248T3 DK95917383T DK95917383T DK0755248T3 DK 0755248 T3 DK0755248 T3 DK 0755248T3 DK 95917383 T DK95917383 T DK 95917383T DK 95917383 T DK95917383 T DK 95917383T DK 0755248 T3 DK0755248 T3 DK 0755248T3
Authority
DK
Denmark
Prior art keywords
gelified
microspheres
applications
processes
preparation
Prior art date
Application number
DK95917383T
Other languages
English (en)
Inventor
Jacques Hauton
Jean-Pierre Salles
Original Assignee
Lipogel
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lipogel filed Critical Lipogel
Application granted granted Critical
Publication of DK0755248T3 publication Critical patent/DK0755248T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5192Processes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • A61K9/1271Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • A61K9/1277Processes for preparing; Proliposomes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5107Excipients; Inactive ingredients
    • A61K9/5123Organic compounds, e.g. fats, sugars
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5107Excipients; Inactive ingredients
    • A61K9/513Organic macromolecular compounds; Dendrimers
    • A61K9/5138Organic macromolecular compounds; Dendrimers obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5107Excipients; Inactive ingredients
    • A61K9/513Organic macromolecular compounds; Dendrimers
    • A61K9/5161Polysaccharides, e.g. alginate, chitosan, cellulose derivatives; Cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5107Excipients; Inactive ingredients
    • A61K9/513Organic macromolecular compounds; Dendrimers
    • A61K9/5169Proteins, e.g. albumin, gelatin
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00Stock material or miscellaneous articles
    • Y10T428/29Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2984Microcapsule with fluid core [includes liposome]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Optics & Photonics (AREA)
  • Biomedical Technology (AREA)
  • Nanotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Dispersion Chemistry (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK95917383T 1994-04-12 1995-04-12 Gelerede mikrosfærer, fremgangsmåde til deres fremstilling og deres anvendelser DK0755248T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9404294A FR2718369B1 (fr) 1994-04-12 1994-04-12 Microsphères gélifiées, leur procédé de préparation et leurs applications.
PCT/FR1995/000473 WO1995027477A1 (fr) 1994-04-12 1995-04-12 Microspheres gelifiees, leur procede de preparation et leurs applications

Publications (1)

Publication Number Publication Date
DK0755248T3 true DK0755248T3 (da) 2000-01-31

Family

ID=9461987

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95917383T DK0755248T3 (da) 1994-04-12 1995-04-12 Gelerede mikrosfærer, fremgangsmåde til deres fremstilling og deres anvendelser

Country Status (18)

Country Link
US (2) US5945120A (da)
EP (1) EP0755248B1 (da)
JP (1) JPH10502332A (da)
KR (1) KR970702027A (da)
AT (1) ATE181665T1 (da)
AU (1) AU692860B2 (da)
BR (1) BR9507350A (da)
CA (1) CA2187551A1 (da)
DE (1) DE69510543T2 (da)
DK (1) DK0755248T3 (da)
ES (1) ES2135728T3 (da)
FI (1) FI964073A (da)
FR (1) FR2718369B1 (da)
GR (1) GR3031108T3 (da)
HU (1) HUT76439A (da)
NZ (1) NZ284825A (da)
RU (1) RU2154465C2 (da)
WO (1) WO1995027477A1 (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2757768B1 (fr) * 1996-12-27 1999-04-02 Biovector Therapeutics Sa Vecteur particulaire homeocharge et composition pharmaceutique ou cosmetique le contenant
FR2764508B1 (fr) * 1997-06-11 2000-10-20 Lipogel Sarl Nouveaux vecteurs liposomaux de principes actifs
FR2764507B1 (fr) * 1997-06-11 2000-10-20 Lipogel Sarl Compositions pulverulentes de liposomes unilamellaires, leur procede de preparation et leurs applications comme complements nutritionnels et comme complements nutritionnels et comme medicaments
US20040126900A1 (en) * 2001-04-13 2004-07-01 Barry Stephen E High affinity peptide- containing nanoparticles
EA200600709A1 (ru) * 2005-12-29 2007-06-29 Дмитрий Александрович Исаев Способ хранения сперматозоидов и продукт для искусственного оплодотворения (варианты)
WO2012155048A1 (en) * 2011-05-11 2012-11-15 Wisconsin Alumni Research Foundation Liposome-encapsulated hydrogels for use in a drug delivery system

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4708861A (en) * 1984-02-15 1987-11-24 The Liposome Company, Inc. Liposome-gel compositions
US5008109A (en) * 1984-05-25 1991-04-16 Vestar, Inc. Vesicle stabilization
US4740375A (en) * 1985-02-25 1988-04-26 Technology Unlimited, Inc. Gelcores
US4839111A (en) * 1987-02-02 1989-06-13 The University Of Tennessee Research Corporation Preparation of solid core liposomes
US4765143A (en) * 1987-02-04 1988-08-23 Cbi Research Corporation Power plant using CO2 as a working fluid
FR2620333B1 (fr) * 1987-09-15 1990-01-05 Inst Nat Sante Rech Med Liposomes, leur procede de preparation et application desdits liposomes comme vecteur de produits
US5104736A (en) * 1988-03-03 1992-04-14 Micro-Pak, Inc. Reinforced paucilamellar lipid vesicles
US5464629A (en) 1993-11-16 1995-11-07 Georgetown University Method of forming hydrogel particles having a controlled size using liposomes

Also Published As

Publication number Publication date
KR970702027A (ko) 1997-05-13
FR2718369B1 (fr) 1996-06-21
NZ284825A (en) 1998-04-27
EP0755248A1 (fr) 1997-01-29
MX9604757A (es) 1998-05-31
GR3031108T3 (en) 1999-12-31
DE69510543D1 (de) 1999-08-05
ES2135728T3 (es) 1999-11-01
CA2187551A1 (fr) 1995-10-19
US5945120A (en) 1999-08-31
FR2718369A1 (fr) 1995-10-13
AU692860B2 (en) 1998-06-18
AU2347595A (en) 1995-10-30
ATE181665T1 (de) 1999-07-15
BR9507350A (pt) 1997-09-23
RU2154465C2 (ru) 2000-08-20
US6221387B1 (en) 2001-04-24
HUT76439A (en) 1997-08-28
EP0755248B1 (fr) 1999-06-30
WO1995027477A1 (fr) 1995-10-19
FI964073A (fi) 1996-10-14
FI964073A0 (fi) 1996-10-11
HU9602801D0 (en) 1996-11-28
DE69510543T2 (de) 2000-01-13
JPH10502332A (ja) 1998-03-03

Similar Documents

Publication Publication Date Title
TR200101513T2 (tr) Benzamid türevleri ve bunların APOB-100 salgılama inhibitörleri olarak kullanımları
ID17794A (id) Bentuk dosis gelatin lunak multi fasa
DK165219C (da) Medikamentholdigt lipidvesikelpraeparat og fremgangsmaade til fremstilling deraf
DE50307127D1 (de) Komponenten fur die herstellung amphoterer liposomen
NO910399D0 (no) Anvendelse av trialkanolaminpolyetere som demulgatorer for olje-i-vann-emulsjoner.
NO904802L (no) Fremgangsmaate for fremstilling av aromatiske aminforbindelser.
DK0755248T3 (da) Gelerede mikrosfærer, fremgangsmåde til deres fremstilling og deres anvendelser
TR199501039A2 (tr) Omega-hidrokarboksilik asit birimleri iceren lineer kopoliyesterleri hazirlama islemi.
DE69221496T2 (de) Formierung von stabilen Liposomen aus Lipidextrakten von Archaeobakterien.
ATE157876T1 (de) Wirkstofffreie liposomen zur behandlung von atherosklerose
DE69519659T2 (de) Chemische Sensibilisierung von Silberhalogenidemulsionen
CA2108039A1 (en) Lipid vesicle containing water-in-oil emulsions
BA96074A (bs) Nove primjene lizozimskog dimera
ATE139442T1 (de) Neue verwendung von linomide (r)
PT1000067E (pt) Tiazolobenzo-heterociclos sua preparacao e medicamentos que os contem
ATE176477T1 (de) Neue phospholipidderivate
DK1001942T3 (da) Polyhydroxybutylpyraziner, deres fremstilling samt medikamenter indeholdende disse forbindelser
NO911922L (no) Fremgangsmaate for fremstilling av semi-ordnede polyamidimider.
ZA961312B (en) Preparation of epoxides by means of aromatic peroxycarboxylic acids.
KR960013242A (ko) 키토산과 구운소금을 함유하는 건강소금 조성물
GR3030190T3 (en) Benzoyl derivatives and synthesis thereof
TR27073A (tr) Ikame edilmis piridinsülfonamid bilesigi ya da tuzu bu bilesik ya da tuzunun hazirlanmasi icin islem ve bu bilesik ya da tuzunu ihtiva eden herbisid.
KR940024222U (ko) 약 포장지의 제조장치
SE9402456D0 (sv) Liphophilic carrier preparations
DE69428127T2 (de) Schädlingsbekämpfungsmittel