DK0737187T3 - Benzoxazinderivater, fremgangsmåder til fremstilling deraf og deres anvendelse som lægemidler - Google Patents

Benzoxazinderivater, fremgangsmåder til fremstilling deraf og deres anvendelse som lægemidler

Info

Publication number
DK0737187T3
DK0737187T3 DK95906357T DK95906357T DK0737187T3 DK 0737187 T3 DK0737187 T3 DK 0737187T3 DK 95906357 T DK95906357 T DK 95906357T DK 95906357 T DK95906357 T DK 95906357T DK 0737187 T3 DK0737187 T3 DK 0737187T3
Authority
DK
Denmark
Prior art keywords
group
formula
representing
pct
hydrogen atom
Prior art date
Application number
DK95906357T
Other languages
English (en)
Inventor
Maurice-Bernard Fleury
Jean-Marc Maurette
Martine Largeron
Original Assignee
Pharmascience Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmascience Lab filed Critical Pharmascience Lab
Application granted granted Critical
Publication of DK0737187T3 publication Critical patent/DK0737187T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25B—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
    • C25B3/00—Electrolytic production of organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/56—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and doubly-bound oxygen atoms bound to the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
    • C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/72—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Psychiatry (AREA)
  • Electrochemistry (AREA)
  • Materials Engineering (AREA)
  • Metallurgy (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK95906357T 1993-12-29 1994-12-29 Benzoxazinderivater, fremgangsmåder til fremstilling deraf og deres anvendelse som lægemidler DK0737187T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9315836A FR2714381B1 (fr) 1993-12-29 1993-12-29 Dérivés de la benzoxazine, leurs procédés d'obtention et leur utilisation en tant que médicaments .
PCT/FR1994/001557 WO1995018114A1 (fr) 1993-12-29 1994-12-29 Derives de la benzoxazine, leurs procedes d'obtention et leur utilisation en tant que medicaments

Publications (1)

Publication Number Publication Date
DK0737187T3 true DK0737187T3 (da) 1999-11-15

Family

ID=9454544

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95906357T DK0737187T3 (da) 1993-12-29 1994-12-29 Benzoxazinderivater, fremgangsmåder til fremstilling deraf og deres anvendelse som lægemidler

Country Status (11)

Country Link
US (1) US5804580A (da)
EP (1) EP0737187B1 (da)
JP (1) JPH09507483A (da)
AT (1) ATE179704T1 (da)
AU (1) AU1510495A (da)
DE (1) DE69418347T2 (da)
DK (1) DK0737187T3 (da)
ES (1) ES2131805T3 (da)
FR (1) FR2714381B1 (da)
GR (1) GR3030567T3 (da)
WO (1) WO1995018114A1 (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2779144B1 (fr) * 1998-05-29 2000-06-30 Adir Nouveaux composes 8-amino-1,4-benzoxaziniques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
GR1007084B (el) * 2008-08-07 2010-11-26 Ευτυχια Κοϊνη 1,4- βενζοξαζινικα αναλογα
CN102552233B (zh) * 2011-12-26 2014-05-14 暨南大学 3,4-二羟基苯甲酸甲酯在制备防治神经退行性疾病药物中的应用
CN113106473B (zh) * 2021-04-14 2022-02-18 南京工业大学 一种通过连续电化学微反应器装置制备1,3-苯并噁嗪衍生物的方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2377202A2 (fr) * 1977-01-12 1978-08-11 Pharmascience Lab Compositions pharmaceutiques contenant de l'hexahydroxy-2,3,4,3',4',5'-benzophenone
US4263322A (en) * 1979-03-01 1981-04-21 Riet Bartholomeus Van T Hydroxy benzohydroxamic acids and benzamides
FR2504917B1 (fr) * 1981-05-04 1987-09-25 Delalande Sa Nouveau systeme oxydant selectif et son application a la preparation de derives aromatiques ortho-dihydroxyles ou ortho-dialcoxyles
US4956372A (en) * 1987-10-02 1990-09-11 Kyorin Pharmaceutical Co., Ltd. Cyclic anthranilic acid derivatives and process for their preparation
US5124325A (en) * 1989-06-13 1992-06-23 Kyorin Pharmaceutical Co., Ltd. Therapeutic agents of metabolic bone disease
US5208247A (en) * 1991-08-01 1993-05-04 American Cyanamid Company Pyridinium compounds which are useful as antagonists of platelet activating factor

Also Published As

Publication number Publication date
ES2131805T3 (es) 1999-08-01
DE69418347D1 (de) 1999-06-10
FR2714381B1 (fr) 1996-02-02
US5804580A (en) 1998-09-08
JPH09507483A (ja) 1997-07-29
WO1995018114A1 (fr) 1995-07-06
FR2714381A1 (fr) 1995-06-30
EP0737187B1 (fr) 1999-05-06
GR3030567T3 (en) 1999-10-29
EP0737187A1 (fr) 1996-10-16
ATE179704T1 (de) 1999-05-15
AU1510495A (en) 1995-07-17
DE69418347T2 (de) 1999-11-18

Similar Documents

Publication Publication Date Title
DE69413542D1 (de) Perhydroisoindolderivate als substanz p antagonisten
DK0696281T3 (da) Hidtil ukendte 5-pyrrolyl-2-pyridylmethylsulfinylbenzimidazolderivater
FI932229A0 (fi) Azabicykliska bryggderivat
DK0737187T3 (da) Benzoxazinderivater, fremgangsmåder til fremstilling deraf og deres anvendelse som lægemidler
NO902866D0 (no) Azetidiner, fremgangsmaate til deres fremstilling og deresanvendelse som mellomprodukter i fremstillingen av forbindelser med antimikrobiell virkning.
DK671588D0 (da) Bisphenylalkylpiperazinderivater og fremgangsmaade til fremstilling deraf
ES2109103T3 (es) Procedimiento para la preparacion de trialquilsilil-7 bacatina iii.
TW198680B (da)
IL112763A0 (en) New n-benzoylmethyl-piperidines
NO952559L (no) N-acyl-pyrrolidiner og medikamenter for behandling eller prevensjon av cholecystokinin- og gastrin-relaterte mangler
DK0694029T3 (da) Fremgangsmåde til fremstilling af forbindelser afledt af beta-alkoxy-acrylsyre
NO973242L (no) Anvendelse av 3,4-difenylkromaner til fremstilling av et farmasöytisk preparat for behandling eller profylakse av idiopatisk eller fysiologisk gynekomasti
DK0950049T3 (da) Diphenylalkyltetrahydropyridiner, fremgangsmåde til fremstilling heraf samt farmaceutiske sammensætninger indeholdende disse
DK0766695T3 (da) Pyrrolidinderivater til behandling af CCK- og gastrinrelaterede sygdomme
RU94022252A (ru) Производные акриловой кислоты, амины, используемые для получения данных производных, способ предотвращения или лечения заболевания