DK0719550T3 - Fremgangsmåde til inhibering af endotoxinfremkaldte virkninger - Google Patents

Fremgangsmåde til inhibering af endotoxinfremkaldte virkninger

Info

Publication number
DK0719550T3
DK0719550T3 DK96104316T DK96104316T DK0719550T3 DK 0719550 T3 DK0719550 T3 DK 0719550T3 DK 96104316 T DK96104316 T DK 96104316T DK 96104316 T DK96104316 T DK 96104316T DK 0719550 T3 DK0719550 T3 DK 0719550T3
Authority
DK
Denmark
Prior art keywords
endotoxin
induced effects
induced
medicament
inhibiting endotoxin
Prior art date
Application number
DK96104316T
Other languages
Danish (da)
English (en)
Inventor
Christer Grimfors
Ellinor Lampen
Svante Lindgren
Goeran Sandberg
Raymond Wahlen
Bjoern Westberg
Original Assignee
Pharmacia Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Ab filed Critical Pharmacia Ab
Application granted granted Critical
Publication of DK0719550T3 publication Critical patent/DK0719550T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/16—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using chemical substances
    • A61L2/18—Liquid substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2103/00—Materials or objects being the target of disinfection or sterilisation
    • A61L2103/05—Living organisms or biological materials

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Communicable Diseases (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • External Artificial Organs (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
DK96104316T 1991-01-09 1991-12-20 Fremgangsmåde til inhibering af endotoxinfremkaldte virkninger DK0719550T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9100059A SE468881B (sv) 1991-01-09 1991-01-09 Anvaendning av vissa foereningar foer framstaellning av laekemedel foer behandling av endotoxininducerade effekter samt saett att avlaegsna endotoxiner ur diverse loesningar

Publications (1)

Publication Number Publication Date
DK0719550T3 true DK0719550T3 (da) 2001-12-10

Family

ID=20381566

Family Applications (2)

Application Number Title Priority Date Filing Date
DK96104316T DK0719550T3 (da) 1991-01-09 1991-12-20 Fremgangsmåde til inhibering af endotoxinfremkaldte virkninger
DK92903332.2T DK0566644T3 (da) 1991-01-09 1991-12-20 Fremgangsmåde til fjernelse af endotoksiner

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK92903332.2T DK0566644T3 (da) 1991-01-09 1991-12-20 Fremgangsmåde til fjernelse af endotoksiner

Country Status (11)

Country Link
EP (4) EP0719550B1 (show.php)
JP (1) JP3200604B2 (show.php)
AT (2) ATE204753T1 (show.php)
AU (1) AU9152891A (show.php)
DE (2) DE69223426T2 (show.php)
DK (2) DK0719550T3 (show.php)
ES (2) ES2163543T3 (show.php)
GR (1) GR3025573T3 (show.php)
PT (1) PT715849E (show.php)
SE (1) SE468881B (show.php)
WO (1) WO1992011847A1 (show.php)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5436270A (en) * 1993-04-07 1995-07-25 National Science Council Method for protecting against endotoxin-induced shock
EP0738146B1 (en) * 1994-01-11 2003-05-02 N.V. Nutricia Method of treating disorders of the animal or human body by administering amino acids
SE9500778D0 (sv) * 1995-03-03 1995-03-03 Pharmacia Ab Process for producing a protein
SE9603068D0 (sv) * 1996-08-23 1996-08-23 Pharmacia & Upjohn Ab Process for purifying a protein
SE9603303D0 (sv) 1996-09-11 1996-09-11 Pharmacia & Upjohn Ab Process for purifying a protein
ATE279919T1 (de) * 1997-08-15 2004-11-15 Carolyn Ann Fairbanks Agmatin für die behandlung neuropathischer schmerzen
US6774102B1 (en) 1999-09-29 2004-08-10 Gambro Dialysatoren Gmbh & Co. Kg Extracorporeal endotoxin removal method
NZ532217A (en) 2001-09-28 2006-12-22 Esperion Therapeutics Inc Use of an alpha helical apolipoprotein or HDL associating protein adapted to be administered locally to prevent or reduce stenosis or restenosis or to stabilize a plaque
SE526038C2 (sv) * 2002-07-08 2005-06-21 Gambro Lundia Ab Polymeraffinitetsmatris, förfarande för framställning därav och anvädning därav
EP1380290A1 (en) 2002-07-09 2004-01-14 Universitair Medisch Centrum Utrecht Cross-beta structure pathway and its therapeutic relevance
EP1732383A4 (en) 2004-04-06 2007-05-02 Cedars Sinai Medical Center PREVENTION AND TREATMENT OF VASCULAR DISEASES WITH RECOMBINANT ADENO ASSOCIATED VIRUS VECTORS THAT CODE APOLIPOPROTEIN A-I AND APOLIPOPROTEIN A-I MILANO
EP2386861A3 (en) 2005-07-13 2012-07-18 Crossbeta Biosciences B.V. Cross-ß structure binding compounds
US8114832B2 (en) 2005-07-13 2012-02-14 Crossbeta Biosciences B.V. Method for detecting and/or removing a protein comprising a cross-beta structure from a pharmaceutical composition
US9375499B2 (en) 2006-07-14 2016-06-28 Wisconsin Alumni Research Foundation Adsorptive membranes for trapping viruses

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA939265A (en) * 1967-11-18 1974-01-01 Yoshitaka Ikezuki Injectable compositions for alleviating the pain incurred from administrations of injections
IT1127322B (it) * 1979-12-28 1986-05-21 Italfarmaco Spa Composizioni farmaceutiche con esaltazione dell'attivita' terapeutica di cortisonici
IT1127321B (it) * 1979-12-28 1986-05-21 Italfarmaco Spa Composizione farmaceutiche aventi specifiche proprieta' terapeutiche nei confronti dell'edema polmonare acuto,di alcuni stati di shock e dell'iperfibrinolisi
JPH01238534A (ja) * 1988-03-17 1989-09-22 Mitsui Toatsu Chem Inc エンドトキシンの除去方法
US5019558A (en) * 1988-05-09 1991-05-28 Georges Cehovic Method for treating memory disturbances using arginine aspartate
GB8929076D0 (en) * 1989-12-22 1990-02-28 Scras Treatment of shock by blocking agents of edrf effect or formation

Also Published As

Publication number Publication date
EP0566644A1 (en) 1993-10-27
EP0719550A3 (show.php) 1996-07-24
DE69223426D1 (de) 1998-01-15
ES2109338T3 (es) 1998-01-16
SE468881B (sv) 1993-04-05
GR3025573T3 (en) 1998-03-31
ATE157866T1 (de) 1997-09-15
EP0719550A2 (en) 1996-07-03
EP0566644B1 (en) 1997-09-10
JPH06504058A (ja) 1994-05-12
SE9100059L (sv) 1992-07-10
DE69223426T2 (de) 1998-03-12
EP0715849B1 (en) 2001-07-25
ES2163543T3 (es) 2002-02-01
PT715849E (pt) 2002-01-30
JP3200604B2 (ja) 2001-08-20
EP0494848A1 (en) 1992-07-15
ATE204753T1 (de) 2001-09-15
EP0715849A1 (en) 1996-06-12
AU9152891A (en) 1992-08-17
EP0719550B1 (en) 2001-08-29
DK0566644T3 (da) 1998-04-27
SE9100059D0 (sv) 1991-01-09
DE69132710T2 (de) 2002-04-18
EP0494848B1 (en) 1997-03-26
DE69132710D1 (de) 2001-10-04
WO1992011847A1 (en) 1992-07-23

Similar Documents

Publication Publication Date Title
EP0870765A4 (show.php)
DE69413237D1 (en) Plättchenaggregationsinhibitoren
DE69200766D1 (en) Phenylamidinderivate als plättchenaggregationsinhibitoren.
CA2159450A1 (en) 1-amidinophenyl-pyrrolidones piperidinones azetinones as platelet aggregation inhibitors
DK0566644T3 (da) Fremgangsmåde til fjernelse af endotoksiner
CA2075173A1 (en) Compounds and methods for inhibition of hiv and related viruses
HU9201578D0 (en) A new peptide and method for producing it
DK0659427T3 (da) 2-Phenyl-3-azoylbenzothiophener til forøgelse af thrombomodulinekspression
IL136100A (en) Biphenylamidine derivatives and pharmaceutical compositions containing the same
MD1560F2 (en) Cyclic compounds, pharmaceutical compositions on base thereof and methods of treatment of infections or diseases provoked by retroviruses.
CA2140927A1 (en) Platelet aggregation inhibitors
DE69530123D1 (en) Plättchenaggregationsinhibitoren
GB9125970D0 (en) New compounds
DK360388A (da) Laegemiddel til behandling af hjerteinsufficiens
AU657423B2 (en) Novel piperidine derivatives and process for preparation thereof
HUT68015A (en) New compound leustroducsin h, its preparation and pharmaceutical compositions containing them
IL110369A0 (en) Pharmaceutical compositions for the prevention and/or treatment of gastrointestinal diseases including ulcer