DK0700384T3 - fremgangsmåde til fremstilling og opløsning af 2-phenyl-3-aminopiperidin - Google Patents

fremgangsmåde til fremstilling og opløsning af 2-phenyl-3-aminopiperidin

Info

Publication number
DK0700384T3
DK0700384T3 DK94910014.3T DK94910014T DK0700384T3 DK 0700384 T3 DK0700384 T3 DK 0700384T3 DK 94910014 T DK94910014 T DK 94910014T DK 0700384 T3 DK0700384 T3 DK 0700384T3
Authority
DK
Denmark
Prior art keywords
phenyl
preparing
aminopiperidine
dissolving
benzylaminopiperidines
Prior art date
Application number
DK94910014.3T
Other languages
Danish (da)
English (en)
Inventor
William M Snyder
Harry A Watson Jr
Glenn E Wilcox
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of DK0700384T3 publication Critical patent/DK0700384T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK94910014.3T 1993-05-28 1994-04-06 fremgangsmåde til fremstilling og opløsning af 2-phenyl-3-aminopiperidin DK0700384T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US6847193A 1993-05-28 1993-05-28

Publications (1)

Publication Number Publication Date
DK0700384T3 true DK0700384T3 (da) 1997-12-08

Family

ID=22082784

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94910014.3T DK0700384T3 (da) 1993-05-28 1994-04-06 fremgangsmåde til fremstilling og opløsning af 2-phenyl-3-aminopiperidin

Country Status (11)

Country Link
US (1) US6436961B1 (el)
EP (1) EP0700384B1 (el)
JP (1) JPH08507297A (el)
AT (1) ATE155456T1 (el)
CA (1) CA2162400A1 (el)
DE (1) DE69404306T2 (el)
DK (1) DK0700384T3 (el)
ES (1) ES2105664T3 (el)
FI (1) FI955708A (el)
GR (1) GR3024592T3 (el)
WO (1) WO1994027966A1 (el)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6239134B1 (en) 1999-03-03 2001-05-29 American Home Products Corp. Diazole derivatives as serotonergic agents
WO2003053929A1 (fr) * 2001-12-21 2003-07-03 Toray Fine Chemicals Co., Ltd. Procede de production de derives de cis-piperidine optiquement actifs
AU2003296373A1 (en) 2002-12-18 2004-07-29 Bayer Cropscience Ag N-(substituted arylmethyl)-4-(disubstituted methyl)piperidines and piperazines
US6995270B2 (en) * 2003-03-17 2006-02-07 Pfizer Inc Hydrogenation process
WO2007075630A1 (en) * 2005-12-22 2007-07-05 Dow Global Technologies Inc. Method for producing 3-aminopiperidine diastereomer
DE102005063192A1 (de) 2005-12-30 2007-07-05 Basf Ag Racematspaltung von 2,6-trans-Dimethyl-morpholin
AU2008210455A1 (en) 2007-01-31 2008-08-07 Vertex Pharmaceuticals Incorporated 2-aminopyridine derivatives useful as kinase inhibitors
WO2010011756A1 (en) 2008-07-23 2010-01-28 Vertex Pharmaceuticals Incorporated Pyrazolopyridine kinase inhibitors
WO2010011768A1 (en) 2008-07-23 2010-01-28 Vertex Pharmaceuticals Incorporated Tri-cyclic pyrazolopyridine kinase inhibitors
US8569337B2 (en) 2008-07-23 2013-10-29 Vertex Pharmaceuticals Incorporated Tri-cyclic pyrazolopyridine kinase inhibitors
EP2313372B1 (en) 2008-08-06 2013-04-10 Vertex Pharmaceuticals Incorporated Aminopyridine kinase inhibitors
AU2010245914A1 (en) 2009-05-06 2011-12-15 Vertex Pharmaceuticals Incorporated Pyrazolopyridines
US9067932B2 (en) 2010-01-27 2015-06-30 Vertex Pharmaceuticals Incorporated Pyrazolopyridine kinase inhibitors
MX2012008643A (es) 2010-01-27 2013-02-26 Vertex Pharma Inhibidores de cinasas de pirazolopiridinas.
EP2550272A1 (en) 2010-01-27 2013-01-30 Vertex Pharmaceuticals Incorporated Pyrazolopyrazine kinase inhibitors
WO2020019247A1 (en) 2018-07-26 2020-01-30 Xw Laboratories, Inc. Compounds as neurokinin-1 receptor antagonists and uses thereof

Family Cites Families (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1139778A (en) 1914-10-12 1915-05-18 Clarence P Landreth Electrochemical process of treating waters, liquids, and sewage.
US2029958A (en) 1933-08-28 1936-02-04 Charles H Lewis Process for the purification of organically polluted waters
BE579912A (el) 1958-07-31
US3442802A (en) 1967-01-25 1969-05-06 Dow Chemical Co Oxidation of aqueous organic dispersions
US3487016A (en) 1967-07-14 1969-12-30 Arde Inc Method of purifying waste water by catalytic oxidation
US3586623A (en) 1968-01-12 1971-06-22 Degussa Process for detoxification of cyanide containing aqueous solutions
US3664951A (en) 1970-07-22 1972-05-23 Pollution Engineering Internat Apparatus and process to treat waste water for pollution control and industrial reuse
DE2050874C3 (de) 1970-10-16 1979-10-18 Fried. Krupp Gmbh, 4300 Essen Verfahren zum Reinigen von Abwässern aus der Papier-, Leder-, Textil-, Reinigungs-, Nahrungsmittel- und Kunststoffindustrie
US4218315A (en) 1974-07-29 1980-08-19 Hartkorn Karl Heinz Oxidation and adsorption method for removing contaminating substances from liquids
US4072596A (en) 1975-04-30 1978-02-07 Westinghouse Electric Corporation Apparatus for removal of contaminants from water
US4029557A (en) 1975-10-15 1977-06-14 Thiokol Corporation Treatment of water containing cyanide
US4007118A (en) 1975-10-16 1977-02-08 Cubic Corporation Ozone oxidation of waste water
US4073873A (en) 1976-03-29 1978-02-14 The Dow Chemical Company Catalytic decomposition of hypochlorite
US4179347A (en) 1978-02-28 1979-12-18 Omnipure, Inc. System for electrocatalytic treatment of waste water streams
EP0022368B1 (en) 1979-07-06 1985-04-10 John Richard Kerridge Method of removing contaminating impurities from leisure pools
US4292175A (en) 1979-08-03 1981-09-29 Omnipure, Inc. Compact electrocatalytic sewage treatment unit for maritime use
US4297333A (en) 1980-07-07 1981-10-27 Ppg Industries, Inc. Method of decomposing hypochlorite ion in a basic solution
DE3042281C2 (de) 1980-11-08 1983-12-08 Akzo Gmbh, 5600 Wuppertal Verfahren und Vorrichtung zur Sauerstoffanreicherung von Flüssigkeiten
US4445990A (en) 1981-11-12 1984-05-01 General Electric Company Electrolytic reactor for cleaning wastewater
US4402836A (en) 1982-12-01 1983-09-06 The United States Of America As Represented By The Secretary Of The Air Force Method for treating contaminated wastewater
DK149624C (da) * 1983-03-07 1987-02-02 Ferrosan As Fremgangsmaade til fremstilling af (+)-trans-3-((4-methoxyphenoxy)-methyl)-1-methyl-4-phenylpiperidin eller et farmaceutisk acceptabelt salt heraf ud fra en blanding af enantiomererne
US4534867A (en) 1983-08-24 1985-08-13 Culligan International Company System for removing iron and/or other chemically reducing substances from potable water
DE3430484A1 (de) 1984-08-18 1986-02-27 Basf Ag, 6700 Ludwigshafen Verfahren zur oxidativen reinigung von abwaessern
GB8519059D0 (en) 1985-07-29 1985-09-04 Ici Plc Hypochlorite decomposition
US4676878A (en) 1986-01-06 1987-06-30 Ephriam Chez Apparatus and method for electronic decomposition of water into aqueous free radicals and free electrons
US4764286A (en) 1986-06-26 1988-08-16 The Dow Chemical Company Catalytic decomposition of sodium hypochlorite in highly alkaline solutions
US4761208A (en) 1986-09-29 1988-08-02 Los Alamos Technical Associates, Inc. Electrolytic method and cell for sterilizing water
US5154836A (en) 1986-11-17 1992-10-13 Ensci, Inc. Process for treating contaminants in aqueous-based materials
DE3705956A1 (de) 1987-02-25 1988-09-08 Dornier System Gmbh Simultane abreicherung von schwermetallen und oxidierbaren schadstoffen aus abwaessern
US4906387A (en) 1988-01-28 1990-03-06 The Water Group, Inc. Method for removing oxidizable contaminants in cooling water used in conjunction with a cooling tower
US4861484A (en) 1988-03-02 1989-08-29 Synlize, Inc. Catalytic process for degradation of organic materials in aqueous and organic fluids to produce environmentally compatible products
US5094734A (en) 1989-08-03 1992-03-10 Torrado Santiago D Water treatment unit
US5108563A (en) 1989-10-02 1992-04-28 Environmental Systems (International) Limited Process for treatment of water and apparatus therefor
UA41251C2 (uk) * 1990-01-04 2001-09-17 Пфайзер, Інк. Гідровані азотвмісні гетероциклічні сполуки, похідні піперидину, фармацевтична композиція та спосіб пригнічення активності речовини р в організмі
US5232929A (en) * 1990-11-28 1993-08-03 Pfizer Inc. 3-aminopiperidine derivatives and related nitrogen containing heterocycles and pharmaceutical compositions and use
US5232604A (en) 1990-01-31 1993-08-03 Modar, Inc. Process for the oxidation of materials in water at supercritical temperatures utilizing reaction rate enhancers
US5288373A (en) 1990-03-15 1994-02-22 Xinyu Yang Process of removing cyanide from waste water
US5364943A (en) * 1991-11-27 1994-11-15 Pfizer Inc. Preparation of substituted piperidines
PL168236B1 (pl) * 1990-05-31 1996-01-31 Pfizer Sposób wytwarzania podstawionych piperydyn PL PL PL
US5190659A (en) 1990-07-06 1993-03-02 International Environmental Systems Inc. Contamination removal system employing filtration and plural ultraviolet and chemical treatment steps and treatment mode controller
US5167777A (en) 1990-10-30 1992-12-01 Olin Corporation Process and apparatus for the removal of oxyhalide species from aqueous solutions
EP0581777A1 (en) * 1991-03-26 1994-02-09 Pfizer Inc. Stereoselective preparation of substituted piperidines
DE4110056A1 (de) 1991-03-27 1992-10-01 Degussa Verfahren zum entgiften von cyanhydrine und/oder nitrile enthaltenden waessrigen loesungen
DE4110055A1 (de) 1991-03-27 1992-10-01 Degussa Verfahren zum entgiften cyanidischer waessriger loesungen
UA39168C2 (uk) * 1991-06-20 2001-06-15 Пфайзер, Інк. Фторалкоксифенільні похідні піперидину або хінуклідину, що є антагоністами речовини p і фармацевтична композиція на їх основі
ES2149767T5 (es) 1991-09-20 2005-06-16 Glaxo Group Limited Nuevo uso medico para antagonistas de taquiquininas.
US5376240A (en) 1991-11-04 1994-12-27 Olin Corporation Process for the removal of oxynitrogen species for aqueous solutions
US5364508A (en) 1992-11-12 1994-11-15 Oleh Weres Electrochemical method and device for generating hydroxyl free radicals and oxidizing chemical substances dissolved in water
US5324438A (en) 1992-11-30 1994-06-28 Cryptonics Corporation Methods of catalytic photooxidation
US5364509A (en) 1993-01-21 1994-11-15 Eltech Systems Corporation Wastewater treatment
US5352370A (en) 1993-01-21 1994-10-04 Calgon Carbon Corporation Method for SOx removal by catalytic carbon
GB9305718D0 (en) * 1993-03-19 1993-05-05 Glaxo Group Ltd Medicaments

Also Published As

Publication number Publication date
CA2162400A1 (en) 1994-12-08
WO1994027966A1 (en) 1994-12-08
US6436961B1 (en) 2002-08-20
JPH08507297A (ja) 1996-08-06
ES2105664T3 (es) 1997-10-16
DE69404306T2 (de) 1997-10-30
GR3024592T3 (en) 1997-12-31
FI955708A0 (fi) 1995-11-27
FI955708A (fi) 1995-11-27
DE69404306D1 (de) 1997-08-21
EP0700384B1 (en) 1997-07-16
ATE155456T1 (de) 1997-08-15
EP0700384A1 (en) 1996-03-13

Similar Documents

Publication Publication Date Title
DK0700384T3 (da) fremgangsmåde til fremstilling og opløsning af 2-phenyl-3-aminopiperidin
MY117274A (en) Polycyclic amine compounds and their enantiomers,their method of preparation and pharmaceutical compositions in which they are present.
RO115522B1 (ro) Derivaţi de indolină, procedee pentru prepararea acestora, compoziţii farmaceutice care îi conţin şi metodă de tratament
MXPA04001940A (es) Tratamiento para desordenes del sistema nervioso central.
CA2112487A1 (en) Method and compositions for treating emesis, nausea and other disorders using optically pure r(+) ondansetron
HK1029595A1 (en) Cyclic antagonists of c5a receptors and g protein-coupled receptors
CA2134964A1 (en) Bridged Aza-Bicyclic Derivatives as Substance P Antagonists
BR1100375A (pt) Composto, composição farmacêutica, e, processo para a preparação de um composto
NO20006645L (no) Ny form av irbesartan, fremgangsmåte for å oppnå den nevnte form og farmasöytiske preparater inneholdende den samme
NO944578L (no) Eksitatoriske aminosyre reseptor antagonister
ATE182333T1 (de) Heterocyclische verbindungen, ihre herstellung und verwendung
FR2723091B1 (fr) Tetrahydropyridine-(6,4-hydroxypiperidine) alkylazoles
ES2067322T3 (es) Lactamas substituidas en n utiles como antagonistas de colecistoquinina.
DK0896539T3 (da) Anvendelse af optisk rent (+)-norcisaprid til behandling af emesis og forstyrrelser i centralnervesystemet
DK0556332T3 (da) Substituerede tetrahydropyridiner og hydroxypiperidiner som midler til behandling af centralnervesystemet
NO20000093L (no) (+)-Norcisaprid nyttig for 5-HT3 og 5-HT4-medierte forstyrrelser
DE69838882D1 (de) Pharmazeutisch wirksame verbindungen und methoden zu ihrer anwendung
MX9605218A (es) Amidas aciclicas y ciclicas novedosas como mejoradores de liberacion de neurotransmisores.
FI103116B1 (fi) Menetelmä uusien, terapeuttisesti käyttökelpoisten, N-substituoitujen atsaheterosyklisten karboksyylihappojohdannaisten valmistamiseksi
DK0996435T3 (da) Aminosyrederivater anvendelige til behandling af slagtilfælde
NO176097C (no) Analogifremgangsmåte for fremstilling av terapeutisk aktive substituerte cykloheksener
MX9603316A (es) (+)-liarozol enantiomericamente puro.
RU93044977A (ru) Ароматические производные аминов и способ их получения
MY115259A (en) Process for the preparation of nmda antagonists
MX9603510A (es) (-)-liarozol enantiomericamente puro.