DK0690715T3 - Topisk og systemisk applikation af busphiron eller derivater deraf til behandling af pathologiske tilstande associeret med immunreaktioner - Google Patents

Topisk og systemisk applikation af busphiron eller derivater deraf til behandling af pathologiske tilstande associeret med immunreaktioner

Info

Publication number
DK0690715T3
DK0690715T3 DK94911001T DK94911001T DK0690715T3 DK 0690715 T3 DK0690715 T3 DK 0690715T3 DK 94911001 T DK94911001 T DK 94911001T DK 94911001 T DK94911001 T DK 94911001T DK 0690715 T3 DK0690715 T3 DK 0690715T3
Authority
DK
Denmark
Prior art keywords
topical
treatment
busphirone
derivatives
conditions associated
Prior art date
Application number
DK94911001T
Other languages
Danish (da)
English (en)
Inventor
Richard J Sharpe
Kenneth A Arndt
Stephen J Galli
Peter C Meltzer
Raj K Razdan
Howard P Sard
Original Assignee
Beth Israel Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/037,271 external-priority patent/US5484788A/en
Priority claimed from US08/037,225 external-priority patent/US5631017A/en
Application filed by Beth Israel Hospital filed Critical Beth Israel Hospital
Application granted granted Critical
Publication of DK0690715T3 publication Critical patent/DK0690715T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Saccharide Compounds (AREA)
DK94911001T 1993-03-26 1994-03-28 Topisk og systemisk applikation af busphiron eller derivater deraf til behandling af pathologiske tilstande associeret med immunreaktioner DK0690715T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/037,271 US5484788A (en) 1993-03-26 1993-03-26 Buspirone as a systemic immunosuppressant
US08/037,225 US5631017A (en) 1993-03-26 1993-03-26 Topical application of buspirone for treatment of pathological conditions associated with immune responses
PCT/US1994/003353 WO1994022448A1 (fr) 1993-03-26 1994-03-28 Utilisation topique ou systemique de buspirone ou de derives de celle-ci pour le traitement de troubles pathologiques associes a des reactions immunitaires

Publications (1)

Publication Number Publication Date
DK0690715T3 true DK0690715T3 (da) 2003-09-22

Family

ID=26713927

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94911001T DK0690715T3 (da) 1993-03-26 1994-03-28 Topisk og systemisk applikation af busphiron eller derivater deraf til behandling af pathologiske tilstande associeret med immunreaktioner

Country Status (10)

Country Link
EP (1) EP0690715B1 (fr)
JP (1) JPH09502699A (fr)
AT (1) ATE241359T1 (fr)
AU (1) AU692764B2 (fr)
CA (1) CA2159091C (fr)
DE (1) DE69432749T2 (fr)
DK (1) DK0690715T3 (fr)
ES (1) ES2201074T3 (fr)
PT (1) PT690715E (fr)
WO (1) WO1994022448A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5521183A (en) * 1994-08-30 1996-05-28 Allergan Use of 5-HT ligands as anti-pruritic agents
US5637314A (en) * 1995-06-07 1997-06-10 Beth Israel Deaconess Medical Center, Inc. Topical and systemic application of buspirone or derivatives thereof for treating atopic dermatitis
WO1997037659A1 (fr) * 1996-04-08 1997-10-16 Sano Corporation Dispositif pour administration transdermique de composes d'azapirone
CN1114401C (zh) * 1998-07-14 2003-07-16 阿尔康实验室公司 11－(3－二甲氨基亚丙基)－6,11－二氢二苯并[b,e]噁庚英－2－乙酸用于制药的新用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE759371A (fr) * 1969-11-24 1971-05-24 Bristol Myers Co Azaspirodecanediones heterocycliques et procedes pour leur preparation
US3976776A (en) * 1972-12-06 1976-08-24 Mead Johnson & Company Tranquilizer process employing N-(heteroarcyclic)piperazinylalkylazaspiroalkanediones
US4963557A (en) * 1987-09-28 1990-10-16 Smithkline Beecham Corporation Immunomodulatory azaspiranes
ATE135216T1 (de) * 1989-08-21 1996-03-15 Beth Israel Hospital Verwendung von spiperone-derivate zur immunosuppression
ATE171067T1 (de) * 1990-03-16 1998-10-15 Beth Israel Hospital Verwendung von spiperon als immunsuppressivum und antiinflammatorisches mittel
SE513429C2 (sv) * 1992-06-03 2000-09-11 Syntello Inc Preparat för aktivering av naturliga mördarceller, vilket preparat innehåller interferon alfa och biogena aminer

Also Published As

Publication number Publication date
WO1994022448A1 (fr) 1994-10-13
CA2159091A1 (fr) 1994-10-13
ES2201074T3 (es) 2004-03-16
EP0690715A1 (fr) 1996-01-10
DE69432749D1 (de) 2003-07-03
JPH09502699A (ja) 1997-03-18
CA2159091C (fr) 2006-12-19
AU692764B2 (en) 1998-06-18
EP0690715A4 (fr) 1997-09-03
DE69432749T2 (de) 2004-04-08
PT690715E (pt) 2003-10-31
AU6369294A (en) 1994-10-24
ATE241359T1 (de) 2003-06-15
EP0690715B1 (fr) 2003-05-28

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