DK0677585T3 - Fremgangsmåde til fremstilling af D-alfa-aminosyrer - Google Patents
Fremgangsmåde til fremstilling af D-alfa-aminosyrerInfo
- Publication number
- DK0677585T3 DK0677585T3 DK95104393.4T DK95104393T DK0677585T3 DK 0677585 T3 DK0677585 T3 DK 0677585T3 DK 95104393 T DK95104393 T DK 95104393T DK 0677585 T3 DK0677585 T3 DK 0677585T3
- Authority
- DK
- Denmark
- Prior art keywords
- amino acids
- alpha
- plasmid
- preparation
- alpha amino
- Prior art date
Links
- 150000007650 D alpha amino acids Chemical class 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 2
- 239000013612 plasmid Substances 0.000 abstract 3
- 238000006243 chemical reaction Methods 0.000 abstract 2
- 230000002255 enzymatic effect Effects 0.000 abstract 2
- 244000005700 microbiome Species 0.000 abstract 2
- 244000063299 Bacillus subtilis Species 0.000 abstract 1
- 235000014469 Bacillus subtilis Nutrition 0.000 abstract 1
- 241000588724 Escherichia coli Species 0.000 abstract 1
- 239000013543 active substance Substances 0.000 abstract 1
- 235000003599 food sweetener Nutrition 0.000 abstract 1
- 150000001469 hydantoins Chemical class 0.000 abstract 1
- 239000000411 inducer Substances 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000000575 pesticide Substances 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 230000000707 stereoselective effect Effects 0.000 abstract 1
- 239000003765 sweetening agent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
- C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
- C12N9/86—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in cyclic amides, e.g. penicillinase (3.5.2)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
- C12P41/006—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
- C12P41/009—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures by reactions involving hydantoins or carbamoylamino compounds
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Analytical Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI940726A IT1274167B (it) | 1994-04-15 | 1994-04-15 | Procedimento per la produzione di d- -amminoacidi |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0677585T3 true DK0677585T3 (da) | 1997-12-29 |
Family
ID=11368611
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK95104393.4T DK0677585T3 (da) | 1994-04-15 | 1995-03-24 | Fremgangsmåde til fremstilling af D-alfa-aminosyrer |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6566105B1 (da) |
| EP (1) | EP0677585B1 (da) |
| JP (1) | JPH0851992A (da) |
| AT (1) | ATE155814T1 (da) |
| DE (1) | DE69500450T2 (da) |
| DK (1) | DK0677585T3 (da) |
| ES (1) | ES2106588T3 (da) |
| GR (1) | GR3024727T3 (da) |
| IT (1) | IT1274167B (da) |
| SI (1) | SI0677585T1 (da) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5824522A (en) * | 1990-12-07 | 1998-10-20 | Kanegafuchi Kagaku Kogyo Kabushiki Kaisha | Recombinant decarbamylases for producing D-α-amino acids |
| IT1269321B (it) * | 1994-04-15 | 1997-03-26 | Eniricerche Spa | Mutanti stabili della d-n- -carbamilasi |
| CN100406553C (zh) * | 1994-12-28 | 2008-07-30 | 钟渊化学工业株式会社 | 生产D-N-氨基甲酰基-α-氨基酸的方法 |
| IT1276163B1 (it) * | 1995-11-23 | 1997-10-27 | Eniricerche Spa | Procedimento migliorato per la preparazione di d-alfa-amminoacidi |
| IT1277125B1 (it) * | 1995-12-21 | 1997-11-04 | Eniricerche Spa | Mutanti termostabili della d-n-alfa-carbamilasi |
| CA2385241A1 (en) * | 1999-09-17 | 2001-03-22 | Sa Bioproducts (Proprietary) Limited | Micro-organisms, their use and method for producing d-amino acids |
| JP4526157B2 (ja) * | 2000-01-27 | 2010-08-18 | ダイセル化学工業株式会社 | Ｄ−アミノアシラーゼ、およびそれをコードする遺伝子 |
| JP4561010B2 (ja) * | 2001-07-10 | 2010-10-13 | 味の素株式会社 | Ｄ−ヒダントインハイドロラーゼをコードするｄｎａ、ｎ−カルバミル−ｄ−アミノ酸ハイドロラーゼをコードするｄｎａ、該遺伝子を含む組み換えｄｎａ、該組み換えｄｎａにより形質転換された細胞、該形質転換細胞を用いるタンパク質の製造方法、および、ｄ−アミノ酸の製造方法 |
| JP4561009B2 (ja) | 2001-07-10 | 2010-10-13 | 味の素株式会社 | Ｄ−ヒダントインハイドロラーゼをコードするｄｎａ、ｎ−カルバミル−ｄ−アミノ酸ハイドロラーゼをコードするｄｎａ、該遺伝子を含む組み換えｄｎａ、該組み換えｄｎａにより形質転換された細胞、該形質転換細胞を用いるタンパク質の製造方法、および、ｄ−アミノ酸の製造方法 |
| CN104830824A (zh) * | 2015-05-15 | 2015-08-12 | 南通荣泰生物科技有限公司 | 一种d型水解酶的生产工艺 |
| CN111621452A (zh) * | 2019-02-28 | 2020-09-04 | 中国科学院微生物研究所 | 一株生产d-对羟基苯甘氨酸的枯草芽孢杆菌 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1109506B (it) * | 1978-05-23 | 1985-12-16 | Snam Progetti | Processo enzimatico-microbiologico per la produzione di amminoacidi otticamente attivi a partire da idantoine e/o carbamil-derivati racemi |
| US5565344A (en) * | 1990-12-07 | 1996-10-15 | Kanegafuchi Kagaku Kogyo Kabushiki Kaisha | Process for production of D-α-amino acids |
| EP0650525B1 (en) * | 1992-06-30 | 2004-05-19 | SmithKline Beecham plc | D-n-carbamoyl-amino acid amidohydrolase and hydantoinase |
-
1994
- 1994-04-15 IT ITMI940726A patent/IT1274167B/it active IP Right Grant
-
1995
- 1995-03-24 DE DE69500450T patent/DE69500450T2/de not_active Expired - Fee Related
- 1995-03-24 EP EP95104393A patent/EP0677585B1/en not_active Expired - Lifetime
- 1995-03-24 SI SI9530018T patent/SI0677585T1/xx not_active IP Right Cessation
- 1995-03-24 AT AT95104393T patent/ATE155814T1/de not_active IP Right Cessation
- 1995-03-24 ES ES95104393T patent/ES2106588T3/es not_active Expired - Lifetime
- 1995-03-24 DK DK95104393.4T patent/DK0677585T3/da active
- 1995-04-03 US US08/415,658 patent/US6566105B1/en not_active Expired - Fee Related
- 1995-04-17 JP JP7115213A patent/JPH0851992A/ja active Pending
-
1997
- 1997-09-16 GR GR970402370T patent/GR3024727T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GR3024727T3 (en) | 1997-12-31 |
| JPH0851992A (ja) | 1996-02-27 |
| ITMI940726A0 (it) | 1994-04-15 |
| ATE155814T1 (de) | 1997-08-15 |
| DE69500450D1 (de) | 1997-08-28 |
| SI0677585T1 (en) | 1997-12-31 |
| DE69500450T2 (de) | 1998-01-22 |
| EP0677585B1 (en) | 1997-07-23 |
| ES2106588T3 (es) | 1997-11-01 |
| ITMI940726A1 (it) | 1995-10-15 |
| EP0677585A1 (en) | 1995-10-18 |
| IT1274167B (it) | 1997-07-15 |
| US6566105B1 (en) | 2003-05-20 |
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