DK0666747T3 - Anvendelse af 17alfa-dihydroequilenin til sænkning af kolesterolniveau - Google Patents

Anvendelse af 17alfa-dihydroequilenin til sænkning af kolesterolniveau

Info

Publication number
DK0666747T3
DK0666747T3 DK94900472T DK94900472T DK0666747T3 DK 0666747 T3 DK0666747 T3 DK 0666747T3 DK 94900472 T DK94900472 T DK 94900472T DK 94900472 T DK94900472 T DK 94900472T DK 0666747 T3 DK0666747 T3 DK 0666747T3
Authority
DK
Denmark
Prior art keywords
dihydroequilenin
lowering cholesterol
17alpha
cholesterol levels
hyperlipidemia
Prior art date
Application number
DK94900472T
Other languages
Danish (da)
English (en)
Inventor
Scott Alan Waschburn
Steven Jay Adelman
Michael Steven Dey
Thomas Boston Clarkson
Original Assignee
Univ Wake Forest
American Home Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Wake Forest, American Home Prod filed Critical Univ Wake Forest
Application granted granted Critical
Publication of DK0666747T3 publication Critical patent/DK0666747T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A61K31/585—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK94900472T 1992-11-02 1993-11-01 Anvendelse af 17alfa-dihydroequilenin til sænkning af kolesterolniveau DK0666747T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US97034892A 1992-11-02 1992-11-02
PCT/US1993/010471 WO1994009789A1 (en) 1992-11-02 1993-11-01 USE OF 17α-DIHYDROEQUILENIN FOR LOWERING CHOLESTEROL

Publications (1)

Publication Number Publication Date
DK0666747T3 true DK0666747T3 (da) 2001-12-27

Family

ID=25516811

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94900472T DK0666747T3 (da) 1992-11-02 1993-11-01 Anvendelse af 17alfa-dihydroequilenin til sænkning af kolesterolniveau

Country Status (16)

Country Link
US (1) US5510342A (ja)
EP (1) EP0666747B1 (ja)
JP (1) JP3621095B2 (ja)
CN (1) CN1089238C (ja)
AT (1) ATE204755T1 (ja)
AU (1) AU5544994A (ja)
CA (1) CA2148357A1 (ja)
DE (1) DE69330680T2 (ja)
DK (1) DK0666747T3 (ja)
ES (1) ES2161750T3 (ja)
IL (1) IL107343A (ja)
PT (1) PT666747E (ja)
SG (1) SG49785A1 (ja)
TW (1) TW237385B (ja)
WO (1) WO1994009789A1 (ja)
ZA (1) ZA938016B (ja)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19524937A1 (de) * 1995-07-08 1997-01-09 Jenapharm Gmbh Pharmazeutische Präparate zur Prophylaxe und Therapie radikalvermittelter Zellschädigungen und zur medikamentösen Substitution beim Mann
US5719137A (en) * 1996-12-03 1998-02-17 Wake Forest University Method of preventing neurodegeneration and cognitive dysfunction using 17α-dihydroequilenin
US7022688B1 (en) 1996-12-10 2006-04-04 Wyeth Use of 17β-dihydroequilenin as an antioxidant
TW422693B (en) * 1996-12-10 2001-02-21 American Home Prod 17<beta>-dihydroequilenin as an antioxidant
US7459445B2 (en) * 2000-03-10 2008-12-02 Duramed Pharmaceuticals, Inc. Estrogenic compounds and topical pharmaceutical formulations of the same
US6660726B2 (en) 2000-03-10 2003-12-09 Endeavor Pharmaceuticals Estrogenic compounds, pharmaceutical compositions thereof, and methods of using same
US6855703B1 (en) 2000-03-10 2005-02-15 Endeavor Pharmaceuticals Pharmaceutical compositions of conjugated estrogens and methods of analyzing mixtures containing estrogenic compounds
US7989436B2 (en) 2003-07-23 2011-08-02 Duramed Pharmaceuticals, Inc. Estrogenic compounds and pharmaceutical formulations comprising the same
SG154323A1 (en) * 2001-03-16 2009-08-28 Wyeth Corp Estrogen replacement therapy
US6992075B2 (en) * 2003-04-04 2006-01-31 Barr Laboratories, Inc. C(14) estrogenic compounds
CA2521471A1 (en) * 2003-04-11 2004-10-28 Barr Laboratories, Inc. Methods of administering estrogens and progestins
WO2006084082A1 (en) * 2005-02-03 2006-08-10 Duramed Pharmaceuticals, Inc. Compositions of unconjugated estrogens and methods for their use
JP2009531712A (ja) * 2006-03-23 2009-09-03 デ グスマン ブレイヤー、エメリタ アポリポタンパク質フィンガープリント技術

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4154820A (en) * 1976-02-23 1979-05-15 Akzona Incorporated Compositions containing alkali metal sulfate salts of conjugated estrogens and antioxidants as stabilizers
US4826831A (en) * 1983-08-05 1989-05-02 Pre Jay Holdings Limited Method of hormonal treatment for menopausal or post-menopausal disorders involving continuous administration of progestogens and estrogens
US4729999A (en) * 1984-10-12 1988-03-08 Bcm Technologies Antiestrogen therapy for symptoms of estrogen deficiency

Also Published As

Publication number Publication date
IL107343A0 (en) 1994-01-25
DE69330680T2 (de) 2002-06-13
JP3621095B2 (ja) 2005-02-16
PT666747E (pt) 2002-02-28
AU5544994A (en) 1994-05-24
EP0666747A1 (en) 1995-08-16
EP0666747B1 (en) 2001-08-29
SG49785A1 (en) 1998-06-15
DE69330680D1 (de) 2001-10-04
ATE204755T1 (de) 2001-09-15
WO1994009789A1 (en) 1994-05-11
CA2148357A1 (en) 1994-05-11
ES2161750T3 (es) 2001-12-16
IL107343A (en) 2003-10-31
CN1094283A (zh) 1994-11-02
TW237385B (ja) 1995-01-01
ZA938016B (en) 1995-04-28
US5510342A (en) 1996-04-23
CN1089238C (zh) 2002-08-21
JPH08503702A (ja) 1996-04-23

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