DK0661987T3 - Morphogeninduceret leverregeneration - Google Patents

Morphogeninduceret leverregeneration

Info

Publication number
DK0661987T3
DK0661987T3 DK93922700T DK93922700T DK0661987T3 DK 0661987 T3 DK0661987 T3 DK 0661987T3 DK 93922700 T DK93922700 T DK 93922700T DK 93922700 T DK93922700 T DK 93922700T DK 0661987 T3 DK0661987 T3 DK 0661987T3
Authority
DK
Denmark
Prior art keywords
liver function
compositions
methods
mammal
correcting
Prior art date
Application number
DK93922700T
Other languages
English (en)
Inventor
Hermann Oppermann
Engin Ozkaynak
David C Rueger
Roy H L Pang
John E Smart
Thangavel Kuberasampath
Charles M Cohen
Original Assignee
Creative Biomolecules Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Creative Biomolecules Inc filed Critical Creative Biomolecules Inc
Application granted granted Critical
Publication of DK0661987T3 publication Critical patent/DK0661987T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1875—Bone morphogenic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/24—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/51—Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005—The prosthesis being constructed from a particular material
    • A61F2310/00365—Proteins; Polypeptides; Degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Transplantation (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Compounds Of Unknown Constitution (AREA)
DK93922700T 1992-09-16 1993-09-16 Morphogeninduceret leverregeneration DK0661987T3 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US94623892A 1992-09-16 1992-09-16
US2933593A 1993-03-04 1993-03-04
US4051093A 1993-03-31 1993-03-31
PCT/US1993/008808 WO1994006449A2 (en) 1992-09-16 1993-09-16 Morphogen-induced liver regeneration

Publications (1)

Publication Number Publication Date
DK0661987T3 true DK0661987T3 (da) 1998-09-14

Family

ID=27363459

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93922700T DK0661987T3 (da) 1992-09-16 1993-09-16 Morphogeninduceret leverregeneration

Country Status (10)

Country Link
EP (1) EP0661987B1 (da)
JP (1) JP3973050B2 (da)
AT (1) ATE162078T1 (da)
AU (1) AU681356B2 (da)
CA (1) CA2144514C (da)
DE (1) DE69316379T2 (da)
DK (1) DK0661987T3 (da)
ES (1) ES2114073T3 (da)
GR (1) GR3026602T3 (da)
WO (1) WO1994006449A2 (da)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2363965C (en) 1991-03-11 2010-05-18 Curis, Inc. Protein-induced morphogenesis
US6287816B1 (en) * 1991-06-25 2001-09-11 Genetics Institute, Inc. BMP-9 compositions
JPH09508908A (ja) * 1994-02-16 1997-09-09 直司 鎌田 免疫抑制化合物およびその調製法
US6498142B1 (en) * 1996-05-06 2002-12-24 Curis, Inc. Morphogen treatment for chronic renal failure
AU757969B2 (en) * 1996-05-06 2003-03-13 Stryker Corporation Therapies for chronic renal failure
AU7142000A (en) * 1996-05-06 2001-01-25 Curis, Inc. Morphogen treatment for chronic renal failure
EP0980252B1 (en) 1997-05-05 2004-10-06 Curis, Inc. Therapies for acute renal failure
AU7473098A (en) * 1997-05-07 1998-11-27 Biogen, Inc. Novel therapies for cystic kidney disease
JP2001526788A (ja) 1997-05-30 2001-12-18 クリエイティブ バイオモレキュールズ，インコーポレイテッド 組織形態形成および活性を評価するための方法
JP2002507896A (ja) * 1997-07-10 2002-03-12 ジェネティックス・インスチチュート・インコーポレーテッド Ｗａ５４５組成物
US7147839B2 (en) 1998-05-29 2006-12-12 Curis, Inc. Methods for evaluating tissue morphogenesis and activity
AU2003247551C1 (en) 2002-06-17 2010-12-09 Thrasos Innovation, Inc. Single domain TDF-related compounds and analogs thereof
JP2008500816A (ja) * 2004-03-31 2008-01-17 ゼンコー・インコーポレイテッド 改善された性質を有するｂｍｐ−７変異体
WO2006009836A2 (en) 2004-06-17 2006-01-26 Thrasos Therapeutics, Inc. Tdf-related compounds and analogs thereof
JP2008169116A (ja) * 2005-04-18 2008-07-24 Tokyo Medical & Dental Univ Ｂｍｐ−７を含む抗ｃ型肝炎ウイルス剤
US8299212B2 (en) 2005-09-20 2012-10-30 Thrasos Therapeutics, Inc. TDF-related compounds and analogs thereof, analogs and bioactive fragments
US20110002897A1 (en) 2009-06-11 2011-01-06 Burnham Institute For Medical Research Directed differentiation of stem cells

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4396601A (en) 1980-03-26 1983-08-02 The Regents Of The University Of Calif. Gene transfer in intact mammals
US4980286A (en) 1985-07-05 1990-12-25 Whitehead Institute For Biomedical Research In vivo introduction and expression of foreign genetic material in epithelial cells
DE3681787D1 (de) 1985-07-05 1991-11-07 Whitehead Biomedical Inst Expression von fremdem genetischem material in epithelzellen.
CA1340581C (en) 1986-11-20 1999-06-08 Joseph P. Vacanti Chimeric neomorphogenesis of organs by controlled cellular implantation using artificial matrices
EP0408649A4 (en) 1988-04-08 1991-11-27 Genetics Institute, Inc. Bone and cartilage inductive compositions
US5011691A (en) 1988-08-15 1991-04-30 Stryker Corporation Osteogenic devices
US4968590A (en) 1988-04-08 1990-11-06 Stryker Corporation Osteogenic proteins and polypeptides
HU201095B (en) 1988-06-14 1990-09-28 Richter Gedeon Vegyeszet New peptides inhibiting the activity of the immune system and pharmaceutical compositions comprising same, as well as process for producing these peptides and compositions
US5104858A (en) 1988-09-29 1992-04-14 Yale University Sensitizing multidrug resistant cells to antitumor agents
US5068323A (en) 1989-04-21 1991-11-26 Merck & Co., Inc. Thermally re-arranged FK-506 derivatives having immunosuppressant activity
CA2031532C (en) 1989-04-25 2003-02-25 Joseph P. Vacanti Method for implanting large volumes of cells on polymeric matrices
US5645591A (en) 1990-05-29 1997-07-08 Stryker Corporation Synthetic bone matrix
EP0564502B1 (en) * 1990-11-27 2002-01-30 The American National Red Cross Tissue sealant and growth factor containing compositions that promote accelerated wound healing
DE69231946T2 (de) 1991-03-11 2002-04-04 Curis Inc Protein-induzierende morphogenese
JP3693338B2 (ja) * 1991-08-30 2005-09-07 キュリス インコーポレイテッド 組織形成因子誘導による炎症反応の調節
US9103603B2 (en) 2009-10-28 2015-08-11 Tai-Her Yang Thermal conductive cylinder installed with U-type core piping and loop piping

Also Published As

Publication number Publication date
AU681356B2 (en) 1997-08-28
WO1994006449A2 (en) 1994-03-31
JP3973050B2 (ja) 2007-09-05
EP0661987B1 (en) 1998-01-14
JPH08501558A (ja) 1996-02-20
ATE162078T1 (de) 1998-01-15
EP0661987A1 (en) 1995-07-12
ES2114073T3 (es) 1998-05-16
GR3026602T3 (en) 1998-07-31
CA2144514C (en) 2002-03-26
DE69316379T2 (de) 1998-07-30
DE69316379D1 (de) 1998-02-19
CA2144514A1 (en) 1994-03-31
WO1994006449A3 (en) 1994-09-01
AU5162393A (en) 1994-04-12

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