GR3026602T3 - Morphogen-induced liver regeneration. - Google Patents

Morphogen-induced liver regeneration.

Info

Publication number
GR3026602T3
GR3026602T3 GR980400798T GR980400798T GR3026602T3 GR 3026602 T3 GR3026602 T3 GR 3026602T3 GR 980400798 T GR980400798 T GR 980400798T GR 980400798 T GR980400798 T GR 980400798T GR 3026602 T3 GR3026602 T3 GR 3026602T3
Authority
GR
Greece
Prior art keywords
liver function
compositions
methods
mammal
correcting
Prior art date
Application number
GR980400798T
Other languages
English (en)
Inventor
Thangavel Kuberasampath
David C Rueger
Hermann Oppermann
Roy H L Pang
Charles M Cohen
Engin Ozkaynak
John E Smart
Original Assignee
Creative Biomolecules Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Creative Biomolecules Inc filed Critical Creative Biomolecules Inc
Publication of GR3026602T3 publication Critical patent/GR3026602T3/el

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • A61K38/1875Bone morphogenic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/22Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/227Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/22Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/24Collagen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • C07K14/51Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005The prosthesis being constructed from a particular material
    • A61F2310/00365Proteins; Polypeptides; Degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
GR980400798T 1992-09-16 1998-04-10 Morphogen-induced liver regeneration. GR3026602T3 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US94623892A 1992-09-16 1992-09-16
US2933593A 1993-03-04 1993-03-04
US4051093A 1993-03-31 1993-03-31
PCT/US1993/008808 WO1994006449A2 (en) 1992-09-16 1993-09-16 Morphogen-induced liver regeneration

Publications (1)

Publication Number Publication Date
GR3026602T3 true GR3026602T3 (en) 1998-07-31

Family

ID=27363459

Family Applications (1)

Application Number Title Priority Date Filing Date
GR980400798T GR3026602T3 (en) 1992-09-16 1998-04-10 Morphogen-induced liver regeneration.

Country Status (10)

Country Link
EP (1) EP0661987B1 (el)
JP (1) JP3973050B2 (el)
AT (1) ATE162078T1 (el)
AU (1) AU681356B2 (el)
CA (1) CA2144514C (el)
DE (1) DE69316379T2 (el)
DK (1) DK0661987T3 (el)
ES (1) ES2114073T3 (el)
GR (1) GR3026602T3 (el)
WO (1) WO1994006449A2 (el)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2104678C (en) 1991-03-11 2002-05-14 Charles M. Cohen Protein-induced morphogenesis
US6287816B1 (en) * 1991-06-25 2001-09-11 Genetics Institute, Inc. BMP-9 compositions
WO1995022559A1 (en) * 1994-02-16 1995-08-24 Naoshi Kamada Immunosuppressive compounds and method of preparing same
AU7142000A (en) * 1996-05-06 2001-01-25 Curis, Inc. Morphogen treatment for chronic renal failure
AU757969B2 (en) * 1996-05-06 2003-03-13 Stryker Corporation Therapies for chronic renal failure
US6498142B1 (en) 1996-05-06 2002-12-24 Curis, Inc. Morphogen treatment for chronic renal failure
ATE278414T1 (de) 1997-05-05 2004-10-15 Curis Inc Therapien zur behandlung von akutem nierenversagen
AU7473098A (en) * 1997-05-07 1998-11-27 Biogen, Inc. Novel therapies for cystic kidney disease
EP1988395A1 (en) 1997-05-30 2008-11-05 Curis, Inc. Methods for evaluating tissue morphogenesis and morphogenic activity
AU749878B2 (en) * 1997-07-10 2002-07-04 Genetics Institute, Llc WA545 compositions
US7147839B2 (en) 1998-05-29 2006-12-12 Curis, Inc. Methods for evaluating tissue morphogenesis and activity
EP2801616A1 (en) 2002-06-17 2014-11-12 Thrasos Innovation, Inc. Single domain TDF-related compounds and analogs thereof
AU2005230854A1 (en) * 2004-03-31 2005-10-20 Xencor, Inc BMP-7 variants with improved properties
CA2571218C (en) 2004-06-17 2015-11-03 William D. Carlson Tdf-related compounds and analogs thereof
JP2008169116A (ja) * 2005-04-18 2008-07-24 Tokyo Medical & Dental Univ Bmp−7を含む抗c型肝炎ウイルス剤
HUE026634T2 (en) 2005-09-20 2016-07-28 Thrasos Innovation Inc TDF-related compounds and analogues thereof
US20110002897A1 (en) 2009-06-11 2011-01-06 Burnham Institute For Medical Research Directed differentiation of stem cells

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4396601A (en) 1980-03-26 1983-08-02 The Regents Of The University Of Calif. Gene transfer in intact mammals
WO1987000201A1 (en) 1985-07-05 1987-01-15 Whitehead Institute For Biomedical Research Epithelial cells expressing foreign genetic material
US4980286A (en) 1985-07-05 1990-12-25 Whitehead Institute For Biomedical Research In vivo introduction and expression of foreign genetic material in epithelial cells
CA1340581C (en) 1986-11-20 1999-06-08 Joseph P. Vacanti Chimeric neomorphogenesis of organs by controlled cellular implantation using artificial matrices
AU645244B2 (en) 1988-04-08 1994-01-13 Genetics Institute, Llc Bone and cartilage inductive compositions
US4968590A (en) 1988-04-08 1990-11-06 Stryker Corporation Osteogenic proteins and polypeptides
US5011691A (en) 1988-08-15 1991-04-30 Stryker Corporation Osteogenic devices
HU201095B (en) 1988-06-14 1990-09-28 Richter Gedeon Vegyeszet New peptides inhibiting the activity of the immune system and pharmaceutical compositions comprising same, as well as process for producing these peptides and compositions
US5104858A (en) 1988-09-29 1992-04-14 Yale University Sensitizing multidrug resistant cells to antitumor agents
US5068323A (en) 1989-04-21 1991-11-26 Merck & Co., Inc. Thermally re-arranged FK-506 derivatives having immunosuppressant activity
ES2072434T3 (es) 1989-04-25 1995-07-16 Childrens Medical Center Implantes para grandes volumenes de celulas sobre matrices polimeras.
US5645591A (en) 1990-05-29 1997-07-08 Stryker Corporation Synthetic bone matrix
CA2097063C (en) 1990-11-27 2006-08-08 Howard P. Greisler Tissue sealant and growth factor containing compositions that promote accelerated wound healing
ATE203166T1 (de) * 1991-03-11 2001-08-15 Curis Inc Protein-induzierende morphogenese
ATE192931T1 (de) 1991-08-30 2000-06-15 Creative Biomolecules Inc Morphogen-induzierte modulation von entzündlichen antworten
US9103603B2 (en) 2009-10-28 2015-08-11 Tai-Her Yang Thermal conductive cylinder installed with U-type core piping and loop piping

Also Published As

Publication number Publication date
WO1994006449A3 (en) 1994-09-01
AU5162393A (en) 1994-04-12
WO1994006449A2 (en) 1994-03-31
AU681356B2 (en) 1997-08-28
DK0661987T3 (da) 1998-09-14
JPH08501558A (ja) 1996-02-20
DE69316379T2 (de) 1998-07-30
EP0661987B1 (en) 1998-01-14
CA2144514C (en) 2002-03-26
ATE162078T1 (de) 1998-01-15
CA2144514A1 (en) 1994-03-31
EP0661987A1 (en) 1995-07-12
JP3973050B2 (ja) 2007-09-05
DE69316379D1 (de) 1998-02-19
ES2114073T3 (es) 1998-05-16

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