DK0656368T4 - Kompositmateriale med lille diameter, som indeholder et vandopløseligt carboxypolysaccharid og magnetisk jernoxid - Google Patents

Kompositmateriale med lille diameter, som indeholder et vandopløseligt carboxypolysaccharid og magnetisk jernoxid

Info

Publication number
DK0656368T4
DK0656368T4 DK94906771T DK94906771T DK0656368T4 DK 0656368 T4 DK0656368 T4 DK 0656368T4 DK 94906771 T DK94906771 T DK 94906771T DK 94906771 T DK94906771 T DK 94906771T DK 0656368 T4 DK0656368 T4 DK 0656368T4
Authority
DK
Denmark
Prior art keywords
water
iron oxide
magnetic iron
composite material
small diameter
Prior art date
Application number
DK94906771T
Other languages
English (en)
Other versions
DK0656368T3 (da
Inventor
Masakatsu Hasegawa
Yoshio Ito
Hisato Yamada
Hideo Nagae
Nahoko Tozawa
Yukari Hino
Kyoji Kito
Shusaburo Hokukoku
Rudiger Lawaczeck
Wolfgang Ebert
Detlef Pfefferer
Susanne Wagner
Mayk Kresse
Original Assignee
Meito Sangyo Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=16866463&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0656368(T4) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Meito Sangyo Kk filed Critical Meito Sangyo Kk
Application granted granted Critical
Publication of DK0656368T3 publication Critical patent/DK0656368T3/da
Publication of DK0656368T4 publication Critical patent/DK0656368T4/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0409—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is not a halogenated organic compound
    • A61K49/0414—Particles, beads, capsules or spheres
    • A61K49/0423—Nanoparticles, nanobeads, nanospheres, nanocapsules, i.e. having a size or diameter smaller than 1 micrometer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/12—Macromolecular compounds
    • A61K49/126—Linear polymers, e.g. dextran, inulin, PEG
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
    • A61K49/1818—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles
    • A61K49/1821—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles
    • A61K49/1824—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles
    • A61K49/1827—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles having a (super)(para)magnetic core, being a solid MRI-active material, e.g. magnetite, or composed of a plurality of MRI-active, organic agents, e.g. Gd-chelates, or nuclei, e.g. Eu3+, encapsulated or entrapped in the core of the coated or functionalised nanoparticle
    • A61K49/1851—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles having a (super)(para)magnetic core, being a solid MRI-active material, e.g. magnetite, or composed of a plurality of MRI-active, organic agents, e.g. Gd-chelates, or nuclei, e.g. Eu3+, encapsulated or entrapped in the core of the coated or functionalised nanoparticle having a (super)(para)magnetic core coated or functionalised with an organic macromolecular compound, i.e. oligomeric, polymeric, dendrimeric organic molecule
    • A61K49/1863—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles having a (super)(para)magnetic core, being a solid MRI-active material, e.g. magnetite, or composed of a plurality of MRI-active, organic agents, e.g. Gd-chelates, or nuclei, e.g. Eu3+, encapsulated or entrapped in the core of the coated or functionalised nanoparticle having a (super)(para)magnetic core coated or functionalised with an organic macromolecular compound, i.e. oligomeric, polymeric, dendrimeric organic molecule the organic macromolecular compound being a polysaccharide or derivative thereof, e.g. chitosan, chitin, cellulose, pectin, starch
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C08B37/0021—Dextran, i.e. (alpha-1,4)-D-glucan; Derivatives thereof, e.g. Sephadex, i.e. crosslinked dextran
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry
DK94906771T 1992-08-05 1993-08-04 Kompositmateriale med lille diameter, som indeholder et vandopløseligt carboxypolysaccharid og magnetisk jernoxid DK0656368T4 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP22779292 1992-08-05
PCT/JP1993/001092 WO1994003501A1 (en) 1992-08-05 1993-08-04 Small-diameter composite composed of water-soluble carboxypolysaccharide and magnetic iron oxide

Publications (2)

Publication Number Publication Date
DK0656368T3 DK0656368T3 (da) 1999-10-25
DK0656368T4 true DK0656368T4 (da) 2003-09-29

Family

ID=16866463

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94906771T DK0656368T4 (da) 1992-08-05 1993-08-04 Kompositmateriale med lille diameter, som indeholder et vandopløseligt carboxypolysaccharid og magnetisk jernoxid

Country Status (9)

Country Link
US (1) US5766572A (da)
EP (1) EP0656368B2 (da)
JP (1) JP3337075B2 (da)
AT (1) ATE179185T1 (da)
DE (1) DE69324591T3 (da)
DK (1) DK0656368T4 (da)
ES (1) ES2130406T5 (da)
GR (1) GR3030030T3 (da)
WO (1) WO1994003501A1 (da)

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DE4428851C2 (de) * 1994-08-04 2000-05-04 Diagnostikforschung Inst Eisen enthaltende Nanopartikel, ihre Herstellung und Anwendung in der Diagnostik und Therapie
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US6203778B1 (en) 1998-12-08 2001-03-20 The Regents Of The University Of California Particulate radiopaque contrast agent for diagnostic imaging and microvascular characterization
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US7169618B2 (en) * 2000-06-28 2007-01-30 Skold Technology Magnetic particles and methods of producing coated magnetic particles
KR20020018260A (ko) * 2000-09-01 2002-03-08 조옥순 자동차 제동장치용 로터의 재질개선 방법
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US6844426B2 (en) 2002-02-06 2005-01-18 Toyo Boseki Kabushiki Kaisha Magnetic carrier capable of binding with protein and purification method of protein utilizing the magnetic carrier
US20030185757A1 (en) * 2002-03-27 2003-10-02 Mayk Kresse Iron-containing nanoparticles with double coating and their use in diagnosis and therapy
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EP1810688A1 (en) * 2004-11-10 2007-07-25 Konica Minolta Medical & Graphic, Inc. Pharmaceutical preparation containing coated magnetic particles and method for production thereof, and diagnosis therapy system
MX2007010371A (es) * 2005-02-25 2008-01-11 Tetralogic Pharmaceuticals Inhibidores dimericos iap.
JP5321772B2 (ja) * 2005-06-15 2013-10-23 戸田工業株式会社 磁性粒子含有医薬用原薬
EP1738773A1 (de) * 2005-06-29 2007-01-03 Schering AG Magnetische Eisenoxidpartikel enthaltende Zusammensetzung und deren Vervendung in bildgebenden Verfahren
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CN101547706B (zh) 2007-04-12 2013-07-10 延世大学校产学协力团 包含含锌磁性金属氧化物纳米颗粒的磁共振成像造影剂
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CN106265593B (zh) 2010-05-26 2019-08-13 通用医疗公司 磁性纳米微粒
JPWO2012026194A1 (ja) * 2010-08-25 2013-10-28 国立大学法人徳島大学 金属酸化物ナノ粒子構造体およびその製造方法
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Also Published As

Publication number Publication date
JP3337075B2 (ja) 2002-10-21
DK0656368T3 (da) 1999-10-25
ES2130406T3 (es) 1999-07-01
DE69324591T2 (de) 1999-08-19
WO1994003501A1 (en) 1994-02-17
DE69324591D1 (de) 1999-05-27
US5766572A (en) 1998-06-16
DE69324591T3 (de) 2004-02-12
ES2130406T5 (es) 2003-12-16
EP0656368A4 (en) 1996-05-08
EP0656368B2 (en) 2003-06-04
EP0656368A1 (en) 1995-06-07
EP0656368B1 (en) 1999-04-21
GR3030030T3 (en) 1999-07-30
ATE179185T1 (de) 1999-05-15

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