DK0655926T3 - Ny sonde til tumordiagnose eller tumorterapi - Google Patents

Ny sonde til tumordiagnose eller tumorterapi

Info

Publication number
DK0655926T3
DK0655926T3 DK93917719T DK93917719T DK0655926T3 DK 0655926 T3 DK0655926 T3 DK 0655926T3 DK 93917719 T DK93917719 T DK 93917719T DK 93917719 T DK93917719 T DK 93917719T DK 0655926 T3 DK0655926 T3 DK 0655926T3
Authority
DK
Denmark
Prior art keywords
pct
tumor
diagnosis
therapy
new probe
Prior art date
Application number
DK93917719T
Other languages
English (en)
Inventor
Peter Gruss
Catharina Maulbecker
Original Assignee
Max Planck Ges Zur Firderung D
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Max Planck Ges Zur Firderung D filed Critical Max Planck Ges Zur Firderung D
Application granted granted Critical
Publication of DK0655926T3 publication Critical patent/DK0655926T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/0004Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/82Translation products from oncogenes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1135Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against oncogenes or tumor suppressor genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/30Chemical structure
    • C12N2310/35Nature of the modification
    • C12N2310/351Conjugate
    • C12N2310/3517Marker; Tag
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Oncology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Plant Pathology (AREA)
  • Diabetes (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Rheumatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
DK93917719T 1992-08-03 1993-08-02 Ny sonde til tumordiagnose eller tumorterapi DK0655926T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4225569A DE4225569C2 (de) 1992-08-03 1992-08-03 Verwendung einer Sonde zur Tumordiagnostik oder Tumortherapie
PCT/EP1993/002051 WO1994003196A1 (de) 1992-08-03 1993-08-02 Neue sonde zur tumordiagnostik oder tumortherapie

Publications (1)

Publication Number Publication Date
DK0655926T3 true DK0655926T3 (da) 1998-09-21

Family

ID=6464707

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93917719T DK0655926T3 (da) 1992-08-03 1993-08-02 Ny sonde til tumordiagnose eller tumorterapi

Country Status (10)

Country Link
US (1) US5747250A (da)
EP (1) EP0655926B1 (da)
JP (1) JPH07509477A (da)
AT (1) ATE162721T1 (da)
CA (1) CA2141678A1 (da)
DE (2) DE4225569C2 (da)
DK (1) DK0655926T3 (da)
ES (1) ES2114615T3 (da)
HK (1) HK1002531A1 (da)
WO (1) WO1994003196A1 (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6028184A (en) * 1996-12-31 2000-02-22 Max-Plank-Gesellschaft Zur Forderung Der Wissenschaften E.V. Pax6 and Pax4 nucleic acid mixtures
DE19605105A1 (de) 1996-02-12 1997-08-14 Gsf Forschungszentrum Umwelt Neue Sonde zur Früherkennung von epithelialen Dysplasien des mehrschichtigen Plattenepithels sowie zur Tumordiagnostik und Tumortherapie von Plattenepithelkarzinomen
EP1288311A3 (en) * 1996-12-31 2004-09-29 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Method for testing small pharmaceutically active molecules in the activation of Pax4 and production of insulin producing beta-cells
ATE310814T1 (de) * 1996-12-31 2005-12-15 Neues verfahren zur überprüfung des differenzierungszustands pankreatischer zellen eines säugetiers
GB9811598D0 (en) * 1998-05-30 1998-07-29 Imp College Innovations Ltd Diagnosis and treatment of cancer
GB9903841D0 (en) 1999-02-20 1999-04-14 Imp College Innovations Ltd Diagnosis and treatment of cancer
WO2001046405A2 (en) * 1999-12-22 2001-06-28 Mcgill University Modulation of pax-2 for controlled apoptosis or survival of cells
WO2001052789A2 (en) 2000-01-20 2001-07-26 The Brigham And Women's Hospital, Inc. PAX8-PPARη NUCLEIC ACID MOLECULES AND POLYPEPTIDES AND USES THEREOF
CN1320634A (zh) * 2000-04-27 2001-11-07 上海博德基因开发有限公司 一种新的多肽——人含配对盒结构域的蛋白20和编码这种多肽的多核苷酸
CN1320616A (zh) * 2000-04-27 2001-11-07 上海博德基因开发有限公司 一种新的多肽——人Pax蛋白17和编码这种多肽的多核苷酸
CN1321681A (zh) * 2000-04-29 2001-11-14 上海博德基因开发有限公司 一种新的多肽——人Pax蛋白11.3和编码这种多肽的多核苷酸
US7601696B1 (en) 2003-08-22 2009-10-13 University Of South Florida Oct-1 as an oncoprotein and use of nucleic acid inhibitors of Oct-1 for cancer treatment
US8080534B2 (en) 2005-10-14 2011-12-20 Phigenix, Inc Targeting PAX2 for the treatment of breast cancer
KR101088885B1 (ko) * 2008-12-23 2011-12-07 연세대학교 산학협력단 바이오프로브, 그 제조방법, 상기를 사용한 분석 장치 및 분석 방법

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU639532B2 (en) * 1989-12-27 1993-07-29 United States of America, as represented by the Secretary, U.S. Department of Commerce, The Diagnostic probe for detecting human stomach cancer
AU660660B2 (en) * 1991-02-08 1995-07-06 Roussel-Uclaf Nucleotide sequences coding for alpha chain variable regions in human lymphocyte receptors and applications thereof

Also Published As

Publication number Publication date
WO1994003196A1 (de) 1994-02-17
DE4225569A1 (de) 1994-02-10
EP0655926A1 (de) 1995-06-07
US5747250A (en) 1998-05-05
HK1002531A1 (en) 1998-08-28
EP0655926B1 (de) 1998-01-28
CA2141678A1 (en) 1994-02-17
ES2114615T3 (es) 1998-06-01
JPH07509477A (ja) 1995-10-19
DE59308082D1 (de) 1998-03-05
DE4225569C2 (de) 1996-04-25
ATE162721T1 (de) 1998-02-15

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