DK0649423T3 - Fremgangsmåde til fremstilling af 1,3-dioxolanderivater - Google Patents

Fremgangsmåde til fremstilling af 1,3-dioxolanderivater

Info

Publication number
DK0649423T3
DK0649423T3 DK93915331.8T DK93915331T DK0649423T3 DK 0649423 T3 DK0649423 T3 DK 0649423T3 DK 93915331 T DK93915331 T DK 93915331T DK 0649423 T3 DK0649423 T3 DK 0649423T3
Authority
DK
Denmark
Prior art keywords
lower alkyl
hydrogen
preparation
piperazino
compounds
Prior art date
Application number
DK93915331.8T
Other languages
English (en)
Inventor
Norman H Dyson
John O Gardner
Anthony Prince
Denis J Kertesz
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Inc filed Critical Syntex Inc
Application granted granted Critical
Publication of DK0649423T3 publication Critical patent/DK0649423T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DK93915331.8T 1992-06-18 1993-06-17 Fremgangsmåde til fremstilling af 1,3-dioxolanderivater DK0649423T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/900,568 US5208331A (en) 1992-06-18 1992-06-18 Process for preparing 1,3-dioxolane derivatives

Publications (1)

Publication Number Publication Date
DK0649423T3 true DK0649423T3 (da) 1996-11-18

Family

ID=25412737

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93915331.8T DK0649423T3 (da) 1992-06-18 1993-06-17 Fremgangsmåde til fremstilling af 1,3-dioxolanderivater

Country Status (10)

Country Link
US (1) US5208331A (da)
EP (1) EP0649423B1 (da)
JP (1) JPH07508002A (da)
AT (1) ATE143958T1 (da)
AU (1) AU4535293A (da)
DE (1) DE69305352T2 (da)
DK (1) DK0649423T3 (da)
ES (1) ES2094551T3 (da)
MX (1) MX9303645A (da)
WO (1) WO1993025549A1 (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5208331A (en) * 1992-06-18 1993-05-04 Syntex (U.S.A.) Inc. Process for preparing 1,3-dioxolane derivatives
US5274108A (en) * 1992-06-18 1993-12-28 Syntex (U.S.A.) Inc. Process for preparing 1,3-dioxolane derivatives
ES2112151B1 (es) * 1995-03-17 1999-09-16 Menarini Lab Nuevos compuestos homoquirales para la preparacion de ketoconazol, terconazol y antifungicos relacionados, procedimiento para su fabricacion y utilizacion de los mismos.

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1364395A (en) * 1972-01-10 1974-08-21 Du Pont Treatment of bis 4-aminocyclohexyl methane salts
US3936470A (en) * 1975-01-27 1976-02-03 Janssen Pharmaceutica N.V. 1,3-Dioxolan-2-ylmethylimidazoles
US4209447A (en) * 1975-01-27 1980-06-24 Janssen Pharmaceutica N.V. Imidazole derivatives and intermediates in their preparation
EP0052905B1 (en) * 1980-11-24 1984-10-03 Janssen Pharmaceutica N.V. Novel (2-aryl-4-phenylthioalkyl-1,3-dioxolan-2-yl-methyl)azole derivatives
US4490540A (en) * 1981-09-14 1984-12-25 Janssen Pharmaceutica N.V. (2-Aryl-4-phenylthioalkyl-1,3-dioxolan-2-ylmethyl)azole derivatives
US4375474A (en) * 1982-02-11 1983-03-01 Syntex (U.S.A.) Inc. Dioxalane containing imidazole compounds, compositions and use
AU614818B2 (en) * 1988-03-28 1991-09-12 Janssen Pharmaceutica N.V. 2-imidazolylmethyl-1,3-dioxolanyl methylthiophenyl carbamate derivatives and their use as antineoplastic agents
US5158949A (en) * 1990-12-20 1992-10-27 Syntex (U.S.A.) Inc. 1,3-dioxolane derivatives as cholesterol-lowering agents
US5208331A (en) * 1992-06-18 1993-05-04 Syntex (U.S.A.) Inc. Process for preparing 1,3-dioxolane derivatives

Also Published As

Publication number Publication date
EP0649423B1 (en) 1996-10-09
DE69305352T2 (de) 1997-03-20
MX9303645A (es) 1994-02-28
DE69305352D1 (de) 1996-11-14
ATE143958T1 (de) 1996-10-15
JPH07508002A (ja) 1995-09-07
EP0649423A1 (en) 1995-04-26
AU4535293A (en) 1994-01-04
US5208331A (en) 1993-05-04
WO1993025549A1 (en) 1993-12-23
ES2094551T3 (es) 1997-01-16

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