DK0647275T3 - Kloning og ekspression af receptoren for gonatotropin-frigörende hormon - Google Patents

Kloning og ekspression af receptoren for gonatotropin-frigörende hormon

Info

Publication number
DK0647275T3
DK0647275T3 DK93915447T DK93915447T DK0647275T3 DK 0647275 T3 DK0647275 T3 DK 0647275T3 DK 93915447 T DK93915447 T DK 93915447T DK 93915447 T DK93915447 T DK 93915447T DK 0647275 T3 DK0647275 T3 DK 0647275T3
Authority
DK
Denmark
Prior art keywords
gnrh
expression
cell lines
products
gonatotropin
Prior art date
Application number
DK93915447T
Other languages
English (en)
Inventor
Stuart C Sealfon
Original Assignee
Sinai School Medicine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25418494&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0647275(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US08/080,386 external-priority patent/US5750366A/en
Application filed by Sinai School Medicine filed Critical Sinai School Medicine
Application granted granted Critical
Publication of DK0647275T3 publication Critical patent/DK0647275T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1138—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against receptors or cell surface proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/723—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G01N33/76—Human chorionic gonadotropin including luteinising hormone, follicle stimulating hormone, thyroid stimulating hormone or their receptors
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • General Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Reproductive Health (AREA)
  • Plant Pathology (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK93915447T 1992-06-23 1993-06-22 Kloning og ekspression af receptoren for gonatotropin-frigörende hormon DK0647275T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US90407292A 1992-06-23 1992-06-23
US08/080,386 US5750366A (en) 1992-06-23 1993-06-21 Cloning and expression of gonadotropin-releasing hormone receptor
PCT/US1993/005965 WO1994000590A1 (en) 1992-06-23 1993-06-22 Cloning and expression of gonadotropin-releasing hormone receptor

Publications (1)

Publication Number Publication Date
DK0647275T3 true DK0647275T3 (da) 2005-01-24

Family

ID=25418494

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93915447T DK0647275T3 (da) 1992-06-23 1993-06-22 Kloning og ekspression af receptoren for gonatotropin-frigörende hormon

Country Status (9)

Country Link
EP (1) EP0647275B2 (da)
JP (1) JP3719712B2 (da)
AT (1) ATE276362T1 (da)
AU (1) AU4542793A (da)
CA (1) CA2138999C (da)
DE (1) DE69333623T3 (da)
DK (1) DK0647275T3 (da)
ES (1) ES2229208T5 (da)
WO (1) WO1994000590A1 (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5985583A (en) * 1992-06-23 1999-11-16 Mount Sinai School Of Medicine Of The City University Of New York Cloning and expression of gonadotropin-releasing hormone receptor
US5688506A (en) * 1994-01-27 1997-11-18 Aphton Corp. Immunogens against gonadotropin releasing hormone
FR2716205B1 (fr) * 1994-02-17 1996-04-12 Rhone Poulenc Rorer Sa Récepteur galanine, acides nucléiques, cellules transformées et utilisations.
US5677184A (en) * 1994-04-19 1997-10-14 Takeda Chemical Industries, Ltd. CHO cells that express human LH-RH receptor
JPH11507518A (ja) * 1995-06-07 1999-07-06 プレーシス ファーマスーティカルズ インコーポレイテッド Ｇ蛋白質とカップルしたレセプターのアゴニスト及びアンタゴニストの機能的バイオアッセイ
AU3388597A (en) * 1996-06-13 1998-01-07 University Of Cape Town Human type ii gonadotropin-releasing hormone receptor
NZ511550A (en) 1997-05-12 2005-03-24 Aphton Corp CCK-B/gastrin receptor inhibitors for the treatment of tumors
WO1999057270A2 (en) * 1998-05-01 1999-11-11 Incyte Pharmaceuticals, Inc. Human receptor molecules
GB9813279D0 (en) * 1998-06-20 1998-08-19 Medical Res Council Modified receptor
WO2000077047A1 (en) * 1999-06-10 2000-12-21 Merck & Co., Inc. Dog gonadotropin releasing hormone receptor
GB9927215D0 (en) * 1999-11-17 2000-01-12 Univ Bristol Hormone receptor expression
WO2001078796A1 (en) * 2000-04-15 2001-10-25 Medical Res Council Type ii gonadotropin-releasing hormone receptor and polynucleotides encoding therefor
FR2825094A1 (fr) * 2001-05-22 2002-11-29 Sod Conseils Rech Applic Nouveau recepteur gnrh humain et ses applications
AU2002249304A1 (en) * 2001-03-01 2002-09-19 Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S.) Novel human gnrh receptor
JP7469225B2 (ja) 2017-06-15 2024-04-16 キャンサー アドヴァンシーズ インク． 腫瘍及び癌に対する体液性及び細胞性免疫を誘発するための組成物及び方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5190931A (en) * 1983-10-20 1993-03-02 The Research Foundation Of State University Of New York Regulation of gene expression by employing translational inhibition of MRNA utilizing interfering complementary MRNA

Also Published As

Publication number Publication date
ATE276362T1 (de) 2004-10-15
CA2138999C (en) 2010-02-23
DE69333623T3 (de) 2014-05-15
EP0647275A1 (en) 1995-04-12
JP3719712B2 (ja) 2005-11-24
ES2229208T5 (es) 2014-03-25
DE69333623D1 (de) 2004-10-21
JPH07509601A (ja) 1995-10-26
EP0647275B2 (en) 2013-12-18
EP0647275A4 (en) 1997-03-12
CA2138999A1 (en) 1994-01-06
ES2229208T3 (es) 2005-04-16
AU4542793A (en) 1994-01-24
DE69333623T2 (de) 2005-09-22
WO1994000590A1 (en) 1994-01-06
EP0647275B1 (en) 2004-09-15

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