WO2002000689A3 - HUMAN G PROTEIN-COUPLED RECEPTOR IGPcR11, AND USES THEREOF - Google Patents

HUMAN G PROTEIN-COUPLED RECEPTOR IGPcR11, AND USES THEREOF Download PDF

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Publication number
WO2002000689A3
WO2002000689A3 PCT/EP2001/007544 EP0107544W WO0200689A3 WO 2002000689 A3 WO2002000689 A3 WO 2002000689A3 EP 0107544 W EP0107544 W EP 0107544W WO 0200689 A3 WO0200689 A3 WO 0200689A3
Authority
WO
WIPO (PCT)
Prior art keywords
igpcr11
protein
receptor
coupled receptor
express
Prior art date
Application number
PCT/EP2001/007544
Other languages
French (fr)
Other versions
WO2002000689A2 (en
Inventor
Frank Wattler
Sigrid Wattler
Paul Trommler
Michael C Nehls
Original Assignee
Ingenium Pharmaceuticals Ag
Frank Wattler
Sigrid Wattler
Paul Trommler
Michael C Nehls
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ingenium Pharmaceuticals Ag, Frank Wattler, Sigrid Wattler, Paul Trommler, Michael C Nehls filed Critical Ingenium Pharmaceuticals Ag
Priority to AU2001281936A priority Critical patent/AU2001281936A1/en
Publication of WO2002000689A2 publication Critical patent/WO2002000689A2/en
Publication of WO2002000689A3 publication Critical patent/WO2002000689A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/723—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

A novel human G protein-coupled receptor (GPcR) protein, IGPcR11, is identified and characterized. IGPcR11-encoding nucleotides, IGPcR11 proteins and fusion proteins, antibodies to the receptor, host cell expression systems, animal models in which the IGPcR11 gene is mutated, recombinant knock-out animals that do not express IGPcR11 and transgenic animals that express an IGPcR11 transgenes are encompassed by the invention, as are compounds that modulate gene expression or receptor activity of IGPcR11 and their use for drug screening, and diagnosis or treatment of diseases, particularly visual dysfunctions associated with signal processing in the occipital lobe of the brain.
PCT/EP2001/007544 2000-06-30 2001-07-02 HUMAN G PROTEIN-COUPLED RECEPTOR IGPcR11, AND USES THEREOF WO2002000689A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001281936A AU2001281936A1 (en) 2000-06-30 2001-07-02 Human g protein-coupled receptor igpcr11, and uses thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21588000P 2000-06-30 2000-06-30
US60/215,880 2000-06-30

Publications (2)

Publication Number Publication Date
WO2002000689A2 WO2002000689A2 (en) 2002-01-03
WO2002000689A3 true WO2002000689A3 (en) 2002-08-22

Family

ID=22804782

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2001/007544 WO2002000689A2 (en) 2000-06-30 2001-07-02 HUMAN G PROTEIN-COUPLED RECEPTOR IGPcR11, AND USES THEREOF

Country Status (2)

Country Link
AU (1) AU2001281936A1 (en)
WO (1) WO2002000689A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113925021B (en) * 2021-10-12 2023-03-03 中国人民解放军军事科学院军事医学研究院 Animal sleep rhythm regulation and control test method

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999015660A1 (en) * 1997-09-24 1999-04-01 Merck & Co., Inc. G-protein coupled glycoprotein hormone receptor hg38
WO1999048921A1 (en) * 1998-03-26 1999-09-30 The Board Of Trustees Of The Leland Stanford Junior University Novel mammalian g-protein coupled receptors having extracellular leucine rich repeat regions
WO2001098351A2 (en) * 2000-06-16 2001-12-27 Incyte Genomics, Inc. G-protein coupled receptors

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999015660A1 (en) * 1997-09-24 1999-04-01 Merck & Co., Inc. G-protein coupled glycoprotein hormone receptor hg38
WO1999048921A1 (en) * 1998-03-26 1999-09-30 The Board Of Trustees Of The Leland Stanford Junior University Novel mammalian g-protein coupled receptors having extracellular leucine rich repeat regions
WO2001098351A2 (en) * 2000-06-16 2001-12-27 Incyte Genomics, Inc. G-protein coupled receptors

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE EM_HUM [online] E.B.I., HINXTON, U.K.; 24 February 1998 (1998-02-24), WHITAKER H: "Human DNA sequence from clone RP5-994E9 on chromosome 6p21.31-22.2", XP002196885, Database accession no. AL035542 *
DATABASE EM_MUS [online] E.B.I. HINXTON, UK; 18 November 1999 (1999-11-18), MATTHEWS L: "Novel 7 transmembrane receptor protein", XP002196884, Database accession no. AL133159 *
DATABASE SWALL [online] E.B.I., HINXTON, UK; 28 March 2000 (2000-03-28), MATTHEWS L: "Novel 7 transmembrane receptor protein", XP002196886, Database accession no. CAB83025 *

Also Published As

Publication number Publication date
WO2002000689A2 (en) 2002-01-03
AU2001281936A1 (en) 2002-01-08

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