DK0626381T3 - Fremstilling af form 1 ranitidinhydrochlorid - Google Patents
Fremstilling af form 1 ranitidinhydrochloridInfo
- Publication number
- DK0626381T3 DK0626381T3 DK93304182.4T DK93304182T DK0626381T3 DK 0626381 T3 DK0626381 T3 DK 0626381T3 DK 93304182 T DK93304182 T DK 93304182T DK 0626381 T3 DK0626381 T3 DK 0626381T3
- Authority
- DK
- Denmark
- Prior art keywords
- ranitidine hydrochloride
- preparation
- prepared
- volume
- solution
- Prior art date
Links
- 229960001520 ranitidine hydrochloride Drugs 0.000 title abstract 5
- GGWBHVILAJZWKJ-KJEVSKRMSA-N ranitidine hydrochloride Chemical compound [H+].[Cl-].[O-][N+](=O)\C=C(/NC)NCCSCC1=CC=C(CN(C)C)O1 GGWBHVILAJZWKJ-KJEVSKRMSA-N 0.000 title abstract 5
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 abstract 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 2
- 239000013078 crystal Substances 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 239000011877 solvent mixture Substances 0.000 abstract 2
- 150000004945 aromatic hydrocarbons Chemical class 0.000 abstract 1
- 238000002425 crystallisation Methods 0.000 abstract 1
- 230000008025 crystallization Effects 0.000 abstract 1
- 239000012458 free base Substances 0.000 abstract 1
- 238000011065 in-situ storage Methods 0.000 abstract 1
- 239000012046 mixed solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/041,354 US5338871A (en) | 1991-12-20 | 1993-04-01 | Preparation of form 1 ranitidine hydrochloride |
| EP93304182A EP0626381B1 (de) | 1993-04-01 | 1993-05-28 | Herstellung der Form 1 von Ranitidin Hydrochlorid |
| CA002099530A CA2099530C (en) | 1993-04-01 | 1993-07-02 | Preparation of form 1 ranitidine hydrochloride |
| AU41794/93A AU674006B2 (en) | 1993-04-01 | 1993-07-06 | Preparation of form 1 ranitidine hydrochloride |
| HU9301980A HU214334B (hu) | 1993-04-01 | 1993-07-08 | Eljárás ranitidin-hidroklorid 1 kristályformájának előállítására |
| ZA934995A ZA934995B (en) | 1993-04-01 | 1993-07-12 | Preparation of form 1 ranitidine hydrochloride |
| NZ260551A NZ260551A (en) | 1993-04-01 | 1994-05-18 | Preparation of form 1 ranitidine hcl crystals |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0626381T3 true DK0626381T3 (da) | 1995-10-02 |
Family
ID=27560579
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK93304182.4T DK0626381T3 (da) | 1993-04-01 | 1993-05-28 | Fremstilling af form 1 ranitidinhydrochlorid |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5338871A (de) |
| EP (1) | EP0626381B1 (de) |
| AT (1) | ATE119894T1 (de) |
| AU (1) | AU674006B2 (de) |
| CA (1) | CA2099530C (de) |
| DE (1) | DE69300088T2 (de) |
| DK (1) | DK0626381T3 (de) |
| ES (1) | ES2069446T3 (de) |
| HU (1) | HU214334B (de) |
| NZ (1) | NZ260551A (de) |
| ZA (1) | ZA934995B (de) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4341310A1 (de) * | 1993-12-03 | 1995-06-08 | Hexal Pharma Gmbh | Tablette oder Kapsel mit einem Gehalt an stabilem Ranitidinhydrochlorid Form 1 |
| CA2120874E (en) * | 1994-04-08 | 2002-01-08 | Keshava Murthy | Form of form 1 ranitidine |
| US5670671A (en) * | 1994-04-08 | 1997-09-23 | Brantford Chemicals Inc. | Process for the production of an improved form of form 1 ranitidine |
| NZ272054A (en) * | 1994-05-13 | 1996-05-28 | Ranbaxy Lab Ltd | Process for producing form 1 ranitidine hydrochloride |
| IN181699B (de) * | 1994-05-13 | 1998-09-05 | Ranbaxy Lab Ltd | |
| DE69504156T2 (de) * | 1994-06-24 | 1998-12-24 | Ranbaxy Laboratories, Ltd., New Delhi | Verfahren zur Herstellung von Ranitidinhydrochlorid in der Kristallform 1 |
| WO1996019232A1 (en) * | 1994-12-19 | 1996-06-27 | Lauteral Limited | Combinations of ranitidine hydrochloride-form 1 and bismuth compounds |
| US5663381A (en) * | 1995-04-21 | 1997-09-02 | Hexal Pharmaceuticals, Inc. | Process for preparing form 1 ranitidine hydrochloride |
| US5686588A (en) * | 1995-08-16 | 1997-11-11 | Yoo; Seo Hong | Amine acid salt compounds and process for the production thereof |
| DE69739561D1 (de) | 1996-06-13 | 2009-10-15 | Sumitomo Chemical Co | Piperidin Derivative als Zwischenprodukte zur Herstellung von Paroxetine und Verfahren zu ihrer Herstellung |
| US20020151729A1 (en) * | 1997-02-26 | 2002-10-17 | Cheng Wen J. | Novel process for the preparation of form 1 ranitidine hydrochloride |
| IE990387A1 (en) * | 1998-06-17 | 2000-12-13 | Russinsky Ltd | A ranitidine base water adduct |
| IT1317858B1 (it) | 2000-02-29 | 2003-07-15 | Pharmexcel S R L | Allomorfo del cloridrato dell'isomero z di derivato dialchilamminofurano, procedimento per la sua produzione e composizione |
| DE102006015960A1 (de) * | 2006-04-04 | 2007-10-11 | Qiagen Gmbh | Gemisch reversibel inhibierter Enzyme |
| JP2013533866A (ja) * | 2010-06-17 | 2013-08-29 | ドクター レディズ ラボラトリーズ リミテッド | ３−アミノピペリジンジヒドロクロリドの単一の鏡像異性体を調製するための方法 |
| WO2015155297A1 (en) | 2014-04-11 | 2015-10-15 | Sanovel Ilac Sanayi Ve Ticaret A.S. | Pharmaceutical combinations of dabigatran and h2-receptor antagonists |
| WO2015169957A1 (en) | 2014-05-09 | 2015-11-12 | Sanovel Ilac Sanayi Ve Ticaret A.S. | Pharmaceutical combinations of rivaroxaban and h2-receptor antagonists |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1181084A (en) * | 1980-01-08 | 1985-01-15 | Glaxo Group Limited | Process for the preparation of a furan derivative |
| GB2084580B (en) * | 1980-10-01 | 1984-07-04 | Glaxo Group Ltd | Aminoalkyl furan derivative |
| IL63968A (en) * | 1980-10-01 | 1985-10-31 | Glaxo Group Ltd | Form 2 ranitidine hydrochloride,its preparation and pharmaceutical compositions containing it |
| DE3211127C1 (de) * | 1982-03-26 | 1983-08-11 | Degussa Ag, 6000 Frankfurt | Verfahren zur Gewinnung von S-(Carboxymethyl)-(R)-cystein und S-(Carboxymethyl)-(S)-cystein |
| US4613688A (en) * | 1982-04-02 | 1986-09-23 | Showa Denko Kabushiki Kaisha | Optical resolution process for DL-cysteine |
| JPH0730064B2 (ja) * | 1989-08-17 | 1995-04-05 | 協和醗酵工業株式会社 | フラン誘導体 |
-
1993
- 1993-04-01 US US08/041,354 patent/US5338871A/en not_active Expired - Fee Related
- 1993-05-28 AT AT93304182T patent/ATE119894T1/de not_active IP Right Cessation
- 1993-05-28 ES ES93304182T patent/ES2069446T3/es not_active Expired - Lifetime
- 1993-05-28 DK DK93304182.4T patent/DK0626381T3/da active
- 1993-05-28 EP EP93304182A patent/EP0626381B1/de not_active Expired - Lifetime
- 1993-05-28 DE DE69300088T patent/DE69300088T2/de not_active Expired - Fee Related
- 1993-07-02 CA CA002099530A patent/CA2099530C/en not_active Expired - Fee Related
- 1993-07-06 AU AU41794/93A patent/AU674006B2/en not_active Ceased
- 1993-07-08 HU HU9301980A patent/HU214334B/hu not_active IP Right Cessation
- 1993-07-12 ZA ZA934995A patent/ZA934995B/xx unknown
-
1994
- 1994-05-18 NZ NZ260551A patent/NZ260551A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU674006B2 (en) | 1996-12-05 |
| ATE119894T1 (de) | 1995-04-15 |
| ZA934995B (en) | 1994-02-11 |
| HU9301980D0 (en) | 1993-09-28 |
| DE69300088T2 (de) | 1995-08-31 |
| HUT68736A (en) | 1995-04-27 |
| EP0626381A1 (de) | 1994-11-30 |
| CA2099530C (en) | 2002-10-08 |
| NZ260551A (en) | 1995-02-24 |
| ES2069446T3 (es) | 1995-05-01 |
| HU214334B (hu) | 1998-03-02 |
| EP0626381B1 (de) | 1995-03-15 |
| CA2099530A1 (en) | 1995-01-03 |
| AU4179493A (en) | 1995-01-27 |
| DE69300088D1 (de) | 1995-04-20 |
| US5338871A (en) | 1994-08-16 |
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