ZA934995B - Preparation of form 1 ranitidine hydrochloride - Google Patents
Preparation of form 1 ranitidine hydrochlorideInfo
- Publication number
- ZA934995B ZA934995B ZA934995A ZA934995A ZA934995B ZA 934995 B ZA934995 B ZA 934995B ZA 934995 A ZA934995 A ZA 934995A ZA 934995 A ZA934995 A ZA 934995A ZA 934995 B ZA934995 B ZA 934995B
- Authority
- ZA
- South Africa
- Prior art keywords
- ranitidine hydrochloride
- preparation
- prepared
- volume
- solution
- Prior art date
Links
- 229960001520 ranitidine hydrochloride Drugs 0.000 title abstract 5
- GGWBHVILAJZWKJ-KJEVSKRMSA-N ranitidine hydrochloride Chemical compound [H+].[Cl-].[O-][N+](=O)\C=C(/NC)NCCSCC1=CC=C(CN(C)C)O1 GGWBHVILAJZWKJ-KJEVSKRMSA-N 0.000 title abstract 5
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 abstract 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 2
- 239000013078 crystal Substances 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 239000011877 solvent mixture Substances 0.000 abstract 2
- 150000004945 aromatic hydrocarbons Chemical class 0.000 abstract 1
- 238000002425 crystallisation Methods 0.000 abstract 1
- 230000008025 crystallization Effects 0.000 abstract 1
- 239000012458 free base Substances 0.000 abstract 1
- 238000011065 in-situ storage Methods 0.000 abstract 1
- 239000012046 mixed solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (12)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/041,354 US5338871A (en) | 1991-12-20 | 1993-04-01 | Preparation of form 1 ranitidine hydrochloride |
AT93304182T ATE119894T1 (de) | 1993-04-01 | 1993-05-28 | Herstellung der form 1 von ranitidin hydrochlorid. |
EP93304182A EP0626381B1 (de) | 1993-04-01 | 1993-05-28 | Herstellung der Form 1 von Ranitidin Hydrochlorid |
ES93304182T ES2069446T3 (es) | 1993-04-01 | 1993-05-28 | Preparacion de hidrocloruro de ranitidina en forma 1. |
DE69300088T DE69300088T2 (de) | 1993-04-01 | 1993-05-28 | Herstellung der Form 1 von Ranitidin Hydrochlorid. |
DK93304182.4T DK0626381T3 (da) | 1993-04-01 | 1993-05-28 | Fremstilling af form 1 ranitidinhydrochlorid |
CA002099530A CA2099530C (en) | 1993-04-01 | 1993-07-02 | Preparation of form 1 ranitidine hydrochloride |
AU41794/93A AU674006B2 (en) | 1993-04-01 | 1993-07-06 | Preparation of form 1 ranitidine hydrochloride |
HU9301980A HU214334B (hu) | 1993-04-01 | 1993-07-08 | Eljárás ranitidin-hidroklorid 1 kristályformájának előállítására |
ZA934995A ZA934995B (en) | 1993-04-01 | 1993-07-12 | Preparation of form 1 ranitidine hydrochloride |
CN93109329A CN1048984C (zh) | 1991-12-20 | 1993-08-10 | 晶形1呋喃硝胺氢氯化物的制备 |
NZ260551A NZ260551A (en) | 1993-04-01 | 1994-05-18 | Preparation of form 1 ranitidine hcl crystals |
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/041,354 US5338871A (en) | 1991-12-20 | 1993-04-01 | Preparation of form 1 ranitidine hydrochloride |
EP93304182A EP0626381B1 (de) | 1993-04-01 | 1993-05-28 | Herstellung der Form 1 von Ranitidin Hydrochlorid |
CA002099530A CA2099530C (en) | 1993-04-01 | 1993-07-02 | Preparation of form 1 ranitidine hydrochloride |
AU41794/93A AU674006B2 (en) | 1993-04-01 | 1993-07-06 | Preparation of form 1 ranitidine hydrochloride |
HU9301980A HU214334B (hu) | 1993-04-01 | 1993-07-08 | Eljárás ranitidin-hidroklorid 1 kristályformájának előállítására |
ZA934995A ZA934995B (en) | 1993-04-01 | 1993-07-12 | Preparation of form 1 ranitidine hydrochloride |
NZ260551A NZ260551A (en) | 1993-04-01 | 1994-05-18 | Preparation of form 1 ranitidine hcl crystals |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA934995B true ZA934995B (en) | 1994-02-11 |
Family
ID=27560579
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA934995A ZA934995B (en) | 1991-12-20 | 1993-07-12 | Preparation of form 1 ranitidine hydrochloride |
Country Status (11)
Country | Link |
---|---|
US (1) | US5338871A (de) |
EP (1) | EP0626381B1 (de) |
AT (1) | ATE119894T1 (de) |
AU (1) | AU674006B2 (de) |
CA (1) | CA2099530C (de) |
DE (1) | DE69300088T2 (de) |
DK (1) | DK0626381T3 (de) |
ES (1) | ES2069446T3 (de) |
HU (1) | HU214334B (de) |
NZ (1) | NZ260551A (de) |
ZA (1) | ZA934995B (de) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4341310A1 (de) * | 1993-12-03 | 1995-06-08 | Hexal Pharma Gmbh | Tablette oder Kapsel mit einem Gehalt an stabilem Ranitidinhydrochlorid Form 1 |
CA2120874E (en) * | 1994-04-08 | 2002-01-08 | Keshava Murthy | Form of form 1 ranitidine |
NZ272054A (en) * | 1994-05-13 | 1996-05-28 | Ranbaxy Lab Ltd | Process for producing form 1 ranitidine hydrochloride |
IN181699B (de) * | 1994-05-13 | 1998-09-05 | Ranbaxy Lab Ltd | |
DE69504156T2 (de) * | 1994-06-24 | 1998-12-24 | Ranbaxy Lab Ltd | Verfahren zur Herstellung von Ranitidinhydrochlorid in der Kristallform 1 |
AU1671295A (en) * | 1994-12-19 | 1996-07-10 | Lauteral Limited | Combinations of ranitidine hydrochloride-form 1 and bismuth compounds |
US5663381A (en) * | 1995-04-21 | 1997-09-02 | Hexal Pharmaceuticals, Inc. | Process for preparing form 1 ranitidine hydrochloride |
US5686588A (en) * | 1995-08-16 | 1997-11-11 | Yoo; Seo Hong | Amine acid salt compounds and process for the production thereof |
EP1394160A1 (de) * | 1996-06-13 | 2004-03-03 | SUMIKA FINE CHEMICALS Co., Ltd. | Verfahren zur Herstellung von kristallinem Paroxetin-Hydrochlorid |
US20020151729A1 (en) * | 1997-02-26 | 2002-10-17 | Cheng Wen J. | Novel process for the preparation of form 1 ranitidine hydrochloride |
AU4055699A (en) * | 1998-06-17 | 2000-01-05 | Russinsky Limited | Ranitidine adduct |
IT1317858B1 (it) | 2000-02-29 | 2003-07-15 | Pharmexcel S R L | Allomorfo del cloridrato dell'isomero z di derivato dialchilamminofurano, procedimento per la sua produzione e composizione |
DE102006015960A1 (de) * | 2006-04-04 | 2007-10-11 | Qiagen Gmbh | Gemisch reversibel inhibierter Enzyme |
US20130172562A1 (en) * | 2010-06-17 | 2013-07-04 | Dr. Reddy's Laboratories, Inc. | Process for the preparation of a single enantiomer of 3-aminopiperidine dihydrochloride |
WO2015155297A1 (en) | 2014-04-11 | 2015-10-15 | Sanovel Ilac Sanayi Ve Ticaret A.S. | Pharmaceutical combinations of dabigatran and h2-receptor antagonists |
WO2015169957A1 (en) | 2014-05-09 | 2015-11-12 | Sanovel Ilac Sanayi Ve Ticaret A.S. | Pharmaceutical combinations of rivaroxaban and h2-receptor antagonists |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1181084A (en) * | 1980-01-08 | 1985-01-15 | Glaxo Group Limited | Process for the preparation of a furan derivative |
IL63968A (en) * | 1980-10-01 | 1985-10-31 | Glaxo Group Ltd | Form 2 ranitidine hydrochloride,its preparation and pharmaceutical compositions containing it |
CY1306A (en) * | 1980-10-01 | 1985-12-06 | Glaxo Group Ltd | Aminoalkyl furan derivative |
DE3211127C1 (de) * | 1982-03-26 | 1983-08-11 | Degussa Ag, 6000 Frankfurt | Verfahren zur Gewinnung von S-(Carboxymethyl)-(R)-cystein und S-(Carboxymethyl)-(S)-cystein |
US4613688A (en) * | 1982-04-02 | 1986-09-23 | Showa Denko Kabushiki Kaisha | Optical resolution process for DL-cysteine |
JPH0730064B2 (ja) * | 1989-08-17 | 1995-04-05 | 協和醗酵工業株式会社 | フラン誘導体 |
-
1993
- 1993-04-01 US US08/041,354 patent/US5338871A/en not_active Expired - Fee Related
- 1993-05-28 DK DK93304182.4T patent/DK0626381T3/da active
- 1993-05-28 ES ES93304182T patent/ES2069446T3/es not_active Expired - Lifetime
- 1993-05-28 DE DE69300088T patent/DE69300088T2/de not_active Expired - Fee Related
- 1993-05-28 EP EP93304182A patent/EP0626381B1/de not_active Expired - Lifetime
- 1993-05-28 AT AT93304182T patent/ATE119894T1/de not_active IP Right Cessation
- 1993-07-02 CA CA002099530A patent/CA2099530C/en not_active Expired - Fee Related
- 1993-07-06 AU AU41794/93A patent/AU674006B2/en not_active Ceased
- 1993-07-08 HU HU9301980A patent/HU214334B/hu not_active IP Right Cessation
- 1993-07-12 ZA ZA934995A patent/ZA934995B/xx unknown
-
1994
- 1994-05-18 NZ NZ260551A patent/NZ260551A/en unknown
Also Published As
Publication number | Publication date |
---|---|
AU674006B2 (en) | 1996-12-05 |
AU4179493A (en) | 1995-01-27 |
ATE119894T1 (de) | 1995-04-15 |
EP0626381B1 (de) | 1995-03-15 |
EP0626381A1 (de) | 1994-11-30 |
DE69300088T2 (de) | 1995-08-31 |
HU214334B (hu) | 1998-03-02 |
CA2099530C (en) | 2002-10-08 |
US5338871A (en) | 1994-08-16 |
DE69300088D1 (de) | 1995-04-20 |
CA2099530A1 (en) | 1995-01-03 |
DK0626381T3 (da) | 1995-10-02 |
HU9301980D0 (en) | 1993-09-28 |
ES2069446T3 (es) | 1995-05-01 |
NZ260551A (en) | 1995-02-24 |
HUT68736A (en) | 1995-04-27 |
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