DK0596891T3 - Aminoalkylsubstituerede 2-amino-5-mercaptothiadiazoler, deres fremstilling og anvendelse - Google Patents

Aminoalkylsubstituerede 2-amino-5-mercaptothiadiazoler, deres fremstilling og anvendelse

Info

Publication number
DK0596891T3
DK0596891T3 DK92910040T DK92910040T DK0596891T3 DK 0596891 T3 DK0596891 T3 DK 0596891T3 DK 92910040 T DK92910040 T DK 92910040T DK 92910040 T DK92910040 T DK 92910040T DK 0596891 T3 DK0596891 T3 DK 0596891T3
Authority
DK
Denmark
Prior art keywords
pct
aminoalkyl
amino
substituted
preparation
Prior art date
Application number
DK92910040T
Other languages
Danish (da)
English (en)
Inventor
Beatrice Rendenbach-Mueller
Hans-Juergen Teschendorf
Liliane Unger
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Application granted granted Critical
Publication of DK0596891T3 publication Critical patent/DK0596891T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D285/00Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01Five-membered rings
    • C07D285/02Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/121,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles
    • C07D285/1251,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
    • C07D285/135Nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
DK92910040T 1991-06-15 1992-05-08 Aminoalkylsubstituerede 2-amino-5-mercaptothiadiazoler, deres fremstilling og anvendelse DK0596891T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4119758A DE4119758A1 (de) 1991-06-15 1991-06-15 Aminoalkylsubstituierte 2-amino-5-mercaptothiadiazole, ihre herstellung und verwendung
PCT/EP1992/001003 WO1992022542A1 (fr) 1991-06-15 1992-05-08 2-amino-5-mercaptothiadiazoles a substituant aminoalkyle, leur fabrication et leur utilisation

Publications (1)

Publication Number Publication Date
DK0596891T3 true DK0596891T3 (da) 1998-10-26

Family

ID=6434012

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92910040T DK0596891T3 (da) 1991-06-15 1992-05-08 Aminoalkylsubstituerede 2-amino-5-mercaptothiadiazoler, deres fremstilling og anvendelse

Country Status (9)

Country Link
US (1) US5401743A (fr)
EP (1) EP0596891B1 (fr)
JP (1) JP3199736B2 (fr)
AT (1) ATE169619T1 (fr)
CA (1) CA2111442A1 (fr)
DE (2) DE4119758A1 (fr)
DK (1) DK0596891T3 (fr)
ES (1) ES2118817T3 (fr)
WO (1) WO1992022542A1 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4425145A1 (de) * 1994-07-15 1996-01-18 Basf Ag Verwendung von Thiazol- und Thiadiazolverbindungen
WO1998030561A1 (fr) * 1997-01-14 1998-07-16 EGIS Gyógyszergyár Rt. NOUVEAUX DERIVES DE 2-(1,2,4-TRIAZOLE-1-YL)-1,3,4-THIADIAZOLE EXERçANT UN EFFET SUR LE SYSTEME NERVEUX CENTRAL ET SUR LE COEUR
DE19728996A1 (de) 1997-07-07 1999-01-14 Basf Ag Triazolverbindungen und deren Verwendung
EP1272187B1 (fr) * 2000-03-27 2008-07-30 Abbott GmbH & Co. KG Ligands du recepteur d3 de la dopamine destines au traitement de la dependance
EP4092013A1 (fr) 2017-06-20 2022-11-23 Imbria Pharmaceuticals, Inc. Compositions et procédés pour augmenter l'efficacité du métabolisme cardiaque
US11780811B2 (en) 2020-06-30 2023-10-10 Imbria Pharmaceuticals, Inc. Methods of synthesizing 2-[4-[(2,3,4-trimethoxyphenyl)methyl]piperazin-1-yl]ethyl pyridine-3-carboxylate
US11530184B2 (en) 2020-06-30 2022-12-20 Imbria Pharmaceuticals, Inc. Crystal forms of 2-[4-[(2,3,4-trimethoxyphenyl)methyl]piperazin-1-yl]ethyl pyridine-3-carboxylate
US11883396B2 (en) 2021-05-03 2024-01-30 Imbria Pharmaceuticals, Inc. Methods of treating kidney conditions using modified forms of trimetazidine

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4074049A (en) * 1976-11-19 1978-02-14 The Dow Chemical Company Antithrombotic 1,3,4-thiadiazole
JPS62153276A (ja) * 1985-12-26 1987-07-08 Yamanouchi Pharmaceut Co Ltd 含窒素5員複素環化合物及びその製造法

Also Published As

Publication number Publication date
US5401743A (en) 1995-03-28
WO1992022542A1 (fr) 1992-12-23
EP0596891B1 (fr) 1998-08-12
JPH06507887A (ja) 1994-09-08
ATE169619T1 (de) 1998-08-15
ES2118817T3 (es) 1998-10-01
CA2111442A1 (fr) 1992-12-23
JP3199736B2 (ja) 2001-08-20
DE4119758A1 (de) 1992-12-17
EP0596891A1 (fr) 1994-05-18
DE59209455D1 (de) 1998-09-17

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