DK0596037T3 - Radiofarmaceutisk produkt, som især har en hjernetropisme, omfattende en nitrid-kompleksforbindelse, samt fremgangsmåde til fremstilling heraf - Google Patents

Radiofarmaceutisk produkt, som især har en hjernetropisme, omfattende en nitrid-kompleksforbindelse, samt fremgangsmåde til fremstilling heraf

Info

Publication number
DK0596037T3
DK0596037T3 DK92917875T DK92917875T DK0596037T3 DK 0596037 T3 DK0596037 T3 DK 0596037T3 DK 92917875 T DK92917875 T DK 92917875T DK 92917875 T DK92917875 T DK 92917875T DK 0596037 T3 DK0596037 T3 DK 0596037T3
Authority
DK
Denmark
Prior art keywords
pct
preparation
complex compound
radiopharmaceutical product
nitride complex
Prior art date
Application number
DK92917875T
Other languages
English (en)
Inventor
Veronique Comazzi
Roberto Pasqualini
Emmanuel Bellande
Jacques Laine
Original Assignee
Cis Bio Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cis Bio Int filed Critical Cis Bio Int
Application granted granted Critical
Publication of DK0596037T3 publication Critical patent/DK0596037T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic System
    • C07F13/005—Compounds without a metal-carbon linkage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0476—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from monodendate ligands, e.g. sestamibi
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/1282—Devices used in vivo and carrying the radioactive therapeutic or diagnostic agent, therapeutic or in vivo diagnostic kits, stents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo
DK92917875T 1991-07-22 1992-07-22 Radiofarmaceutisk produkt, som især har en hjernetropisme, omfattende en nitrid-kompleksforbindelse, samt fremgangsmåde til fremstilling heraf DK0596037T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9109231A FR2679452B1 (fr) 1991-07-22 1991-07-22 Produit radiopharmaceutique ayant notamment un tropisme cerebral, comportant un complexe nitruro d'un metal de transition, et son procede de preparation.
PCT/FR1992/000718 WO1993001839A1 (fr) 1991-07-22 1992-07-22 Produit radiopharmaceutique ayant notamment un tropisme cerebral comportant un complexe nitruro d'un metal de transition, et son procede de preparation

Publications (1)

Publication Number Publication Date
DK0596037T3 true DK0596037T3 (da) 2001-08-06

Family

ID=9415380

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92917875T DK0596037T3 (da) 1991-07-22 1992-07-22 Radiofarmaceutisk produkt, som især har en hjernetropisme, omfattende en nitrid-kompleksforbindelse, samt fremgangsmåde til fremstilling heraf

Country Status (12)

Country Link
US (1) US5496929A (da)
EP (1) EP0596037B1 (da)
JP (1) JPH07500816A (da)
AT (1) ATE200867T1 (da)
AU (1) AU662351B2 (da)
CA (1) CA2113830A1 (da)
DE (1) DE69231811T2 (da)
DK (1) DK0596037T3 (da)
ES (1) ES2157905T3 (da)
FR (1) FR2679452B1 (da)
GR (1) GR3036304T3 (da)
WO (1) WO1993001839A1 (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5380747A (en) * 1992-10-30 1995-01-10 Emory University Treatment for atherosclerosis and other cardiovascular and inflammatory diseases
US5807884A (en) * 1992-10-30 1998-09-15 Emory University Treatment for atherosclerosis and other cardiovascular and inflammatory diseases
US5821260A (en) * 1992-10-30 1998-10-13 Emory University Treatment for atherosclerosis and other cardiovascular and inflammatory diseases
US5750088A (en) * 1993-03-30 1998-05-12 The Dupont Merck Pharmaceutical Company Stable hydrazones linked to a peptide moiety as reagents for the preparation of radiopharmaceuticals
US5744120A (en) * 1993-03-30 1998-04-28 The Dupont Merick Pharmaceutical Company Ternary radiopharmaceutical complexes
US5792787A (en) * 1995-06-07 1998-08-11 Emory University Treatment for atherosclerosis and other cardiovascular and inflammatory diseases
FR2736834B1 (fr) * 1995-07-17 1997-08-29 Cis Bio Int Produits radiopharmaceutiques a tropisme cardiaque comportant un complexe nitruro d'un metal de transition et ayant une clairance myocardique rapide
KR100554563B1 (ko) 1996-12-18 2006-03-03 니혼 메디피직스 가부시키가이샤 방사성 전이 금속 질화물 헤테로-착물
US7445765B2 (en) 2000-07-28 2008-11-04 Nihon Medi-Physics Co., Ltd. Radiopharmaceutical for diagnostic imaging containing a technetium-99m nitride heterocomplex
ES2369027T3 (es) 2006-01-20 2011-11-24 Nihon Medi-Physics Co., Ltd. Compuesto intermedio de un complejo de nitruro de tecnecio para la formación de imágenes radiodiagnósticas.
EP2426107A1 (en) * 2010-08-05 2012-03-07 Universitat Autònoma De Barcelona Transition metal conjugated radiopharmaceuticals useful as therapeutic and/or diagnostic agents

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0166746B1 (en) * 1983-12-29 1991-04-24 The Commonwealth Of Australia Preparation of ?99m tc radiopharmaceuticals
US5279811A (en) * 1987-02-18 1994-01-18 The Du Pont Merck Pharmaceutical Company Ester-substituted diaminedithiols and radiolabeled complexes thereof
US5301278A (en) * 1988-04-29 1994-04-05 International Business Machines Corporation Flexible dynamic memory controller
EP0445190B1 (fr) * 1988-11-25 1993-09-15 Cis Bio International Produit radiopharmaceutique ayant notamment un tropisme cardiaque comportant un complexe nitruro d'un metal de transition, et son procede de preparation
CA2085364A1 (en) * 1990-06-18 1991-12-19 Alfons M. Verbruggen Metal-radionuclide complex comprising isonitrile ligands
FR2664166A1 (fr) * 1990-07-04 1992-01-10 Cis Bio Int Procede de preparation de complexes nitruro de metaux de transition utilisables comme produits radiopharmaceutiques ou pour la synthese de nouveaux produits radiopharmaceutiques.

Also Published As

Publication number Publication date
FR2679452A1 (fr) 1993-01-29
EP0596037B1 (fr) 2001-05-02
FR2679452B1 (fr) 1993-11-12
US5496929A (en) 1996-03-05
CA2113830A1 (en) 1993-01-23
WO1993001839A1 (fr) 1993-02-04
DE69231811T2 (de) 2001-11-22
ES2157905T3 (es) 2001-09-01
EP0596037A1 (fr) 1994-05-11
AU662351B2 (en) 1995-08-31
ATE200867T1 (de) 2001-05-15
DE69231811D1 (de) 2001-06-07
AU2432292A (en) 1993-02-23
JPH07500816A (ja) 1995-01-26
GR3036304T3 (en) 2001-10-31

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