ATE200867T1 - Uebergangsmetall-nitridokomplex enthaltendes radiopharmazeutisches produkt mit einer neigung zum gehirn, verfahren zu deren herstellung - Google Patents
Uebergangsmetall-nitridokomplex enthaltendes radiopharmazeutisches produkt mit einer neigung zum gehirn, verfahren zu deren herstellungInfo
- Publication number
- ATE200867T1 ATE200867T1 AT92917875T AT92917875T ATE200867T1 AT E200867 T1 ATE200867 T1 AT E200867T1 AT 92917875 T AT92917875 T AT 92917875T AT 92917875 T AT92917875 T AT 92917875T AT E200867 T1 ATE200867 T1 AT E200867T1
- Authority
- AT
- Austria
- Prior art keywords
- transition metal
- production
- pct
- complex containing
- radiopharmaceutical product
- Prior art date
Links
- 229910052723 transition metal Inorganic materials 0.000 title abstract 3
- 150000003624 transition metals Chemical class 0.000 title abstract 3
- 239000012217 radiopharmaceutical Substances 0.000 title abstract 2
- 210000004556 brain Anatomy 0.000 title 1
- -1 Tc99m Chemical class 0.000 abstract 1
- 230000002490 cerebral effect Effects 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 229910052711 selenium Inorganic materials 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 230000010415 tropism Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic Table
- C07F13/005—Compounds without a metal-carbon linkage
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
- A61K51/0476—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from monodendate ligands, e.g. sestamibi
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
- A61K51/1282—Devices used in vivo and carrying the radioactive therapeutic or diagnostic agent, therapeutic or in vivo diagnostic kits, stents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Optics & Photonics (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9109231A FR2679452B1 (fr) | 1991-07-22 | 1991-07-22 | Produit radiopharmaceutique ayant notamment un tropisme cerebral, comportant un complexe nitruro d'un metal de transition, et son procede de preparation. |
| PCT/FR1992/000718 WO1993001839A1 (fr) | 1991-07-22 | 1992-07-22 | Produit radiopharmaceutique ayant notamment un tropisme cerebral comportant un complexe nitruro d'un metal de transition, et son procede de preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE200867T1 true ATE200867T1 (de) | 2001-05-15 |
Family
ID=9415380
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT92917875T ATE200867T1 (de) | 1991-07-22 | 1992-07-22 | Uebergangsmetall-nitridokomplex enthaltendes radiopharmazeutisches produkt mit einer neigung zum gehirn, verfahren zu deren herstellung |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US5496929A (de) |
| EP (1) | EP0596037B1 (de) |
| JP (1) | JPH07500816A (de) |
| AT (1) | ATE200867T1 (de) |
| AU (1) | AU662351B2 (de) |
| CA (1) | CA2113830A1 (de) |
| DE (1) | DE69231811T2 (de) |
| DK (1) | DK0596037T3 (de) |
| ES (1) | ES2157905T3 (de) |
| FR (1) | FR2679452B1 (de) |
| GR (1) | GR3036304T3 (de) |
| WO (1) | WO1993001839A1 (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5821260A (en) * | 1992-10-30 | 1998-10-13 | Emory University | Treatment for atherosclerosis and other cardiovascular and inflammatory diseases |
| US5380747A (en) * | 1992-10-30 | 1995-01-10 | Emory University | Treatment for atherosclerosis and other cardiovascular and inflammatory diseases |
| US5807884A (en) * | 1992-10-30 | 1998-09-15 | Emory University | Treatment for atherosclerosis and other cardiovascular and inflammatory diseases |
| US5744120A (en) * | 1993-03-30 | 1998-04-28 | The Dupont Merick Pharmaceutical Company | Ternary radiopharmaceutical complexes |
| US5750088A (en) * | 1993-03-30 | 1998-05-12 | The Dupont Merck Pharmaceutical Company | Stable hydrazones linked to a peptide moiety as reagents for the preparation of radiopharmaceuticals |
| US5792787A (en) * | 1995-06-07 | 1998-08-11 | Emory University | Treatment for atherosclerosis and other cardiovascular and inflammatory diseases |
| FR2736834B1 (fr) * | 1995-07-17 | 1997-08-29 | Cis Bio Int | Produits radiopharmaceutiques a tropisme cardiaque comportant un complexe nitruro d'un metal de transition et ayant une clairance myocardique rapide |
| CA2275451C (en) * | 1996-12-18 | 2007-01-02 | Nihon Medi-Physics Co., Ltd. | Radioactive technetium and rhenium nitride heterocomplexes |
| DE60136073D1 (de) | 2000-07-28 | 2008-11-20 | Nihon Mediphysics Co Ltd | Technitium-99m nitrid hetero-komplex radiopharmazeutisches mittel zur bilderzeugung |
| WO2007083395A1 (en) | 2006-01-20 | 2007-07-26 | Nihon Medi-Physics Co., Ltd. | Intermediate compound of technetium nitride complex for radiodiagnostic imaging |
| EP2426107A1 (de) * | 2010-08-05 | 2012-03-07 | Universitat Autònoma De Barcelona | Übergangsmetallkonjugierte Radiopharmazeutika als Therapie- und/oder Diagnosemittel |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61501087A (ja) * | 1983-12-29 | 1986-05-29 | オ−ストラリア国 | テクネチウム−９９ｍ−標識放射医薬の製造 |
| US5279811A (en) * | 1987-02-18 | 1994-01-18 | The Du Pont Merck Pharmaceutical Company | Ester-substituted diaminedithiols and radiolabeled complexes thereof |
| US5301278A (en) * | 1988-04-29 | 1994-04-05 | International Business Machines Corporation | Flexible dynamic memory controller |
| US5288476A (en) * | 1988-11-25 | 1994-02-22 | Cis Bio International | Radiopharmaceutical product more particularly having a cardiac tropism incorporating a nitride complex of a transition metal and its preparation process |
| WO1991019516A1 (en) * | 1990-06-18 | 1991-12-26 | Mallinckrodt Medical, Inc. | Metal-radionuclide complex comprising isonitrile ligands |
| FR2664166A1 (fr) * | 1990-07-04 | 1992-01-10 | Cis Bio Int | Procede de preparation de complexes nitruro de metaux de transition utilisables comme produits radiopharmaceutiques ou pour la synthese de nouveaux produits radiopharmaceutiques. |
-
1991
- 1991-07-22 FR FR9109231A patent/FR2679452B1/fr not_active Expired - Fee Related
-
1992
- 1992-07-22 CA CA002113830A patent/CA2113830A1/en not_active Abandoned
- 1992-07-22 WO PCT/FR1992/000718 patent/WO1993001839A1/fr not_active Ceased
- 1992-07-22 EP EP92917875A patent/EP0596037B1/de not_active Expired - Lifetime
- 1992-07-22 JP JP5502648A patent/JPH07500816A/ja active Pending
- 1992-07-22 DE DE69231811T patent/DE69231811T2/de not_active Expired - Fee Related
- 1992-07-22 DK DK92917875T patent/DK0596037T3/da active
- 1992-07-22 AU AU24322/92A patent/AU662351B2/en not_active Ceased
- 1992-07-22 AT AT92917875T patent/ATE200867T1/de not_active IP Right Cessation
- 1992-07-22 ES ES92917875T patent/ES2157905T3/es not_active Expired - Lifetime
-
1994
- 1994-07-25 US US08/178,244 patent/US5496929A/en not_active Expired - Fee Related
-
2001
- 2001-07-31 GR GR20010401154T patent/GR3036304T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE69231811T2 (de) | 2001-11-22 |
| CA2113830A1 (en) | 1993-01-23 |
| FR2679452A1 (fr) | 1993-01-29 |
| AU2432292A (en) | 1993-02-23 |
| JPH07500816A (ja) | 1995-01-26 |
| GR3036304T3 (en) | 2001-10-31 |
| DE69231811D1 (de) | 2001-06-07 |
| DK0596037T3 (da) | 2001-08-06 |
| FR2679452B1 (fr) | 1993-11-12 |
| EP0596037A1 (de) | 1994-05-11 |
| US5496929A (en) | 1996-03-05 |
| AU662351B2 (en) | 1995-08-31 |
| WO1993001839A1 (fr) | 1993-02-04 |
| EP0596037B1 (de) | 2001-05-02 |
| ES2157905T3 (es) | 2001-09-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |