DK0592434T3 - Forbedret fremgangsmåde til syntese af oligomerer - Google Patents

Forbedret fremgangsmåde til syntese af oligomerer

Info

Publication number
DK0592434T3
DK0592434T3 DK91919675T DK91919675T DK0592434T3 DK 0592434 T3 DK0592434 T3 DK 0592434T3 DK 91919675 T DK91919675 T DK 91919675T DK 91919675 T DK91919675 T DK 91919675T DK 0592434 T3 DK0592434 T3 DK 0592434T3
Authority
DK
Denmark
Prior art keywords
oligomers
synthesis
improved method
methods
result
Prior art date
Application number
DK91919675T
Other languages
Danish (da)
English (en)
Inventor
Robert E Klem
Timothy A Riley
William B Marvin
Original Assignee
Genta Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genta Inc filed Critical Genta Inc
Application granted granted Critical
Publication of DK0592434T3 publication Critical patent/DK0592434T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK91919675T 1990-10-26 1991-10-21 Forbedret fremgangsmåde til syntese af oligomerer DK0592434T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US60579090A 1990-10-26 1990-10-26
PCT/US1991/007630 WO1992007864A1 (en) 1990-10-26 1991-10-21 Improved process for the synthesis of oligomers

Publications (1)

Publication Number Publication Date
DK0592434T3 true DK0592434T3 (da) 1999-06-21

Family

ID=24425218

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91919675T DK0592434T3 (da) 1990-10-26 1991-10-21 Forbedret fremgangsmåde til syntese af oligomerer

Country Status (14)

Country Link
US (1) US5726300A (OSRAM)
EP (1) EP0592434B1 (OSRAM)
JP (1) JPH06509542A (OSRAM)
AT (1) ATE171947T1 (OSRAM)
AU (1) AU669103B2 (OSRAM)
CA (1) CA2094803A1 (OSRAM)
DE (1) DE69130331T2 (OSRAM)
DK (1) DK0592434T3 (OSRAM)
ES (1) ES2124231T3 (OSRAM)
IE (1) IE913761A1 (OSRAM)
IL (1) IL99844A (OSRAM)
NZ (1) NZ240325A (OSRAM)
TW (1) TW216423B (OSRAM)
WO (1) WO1992007864A1 (OSRAM)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993012135A1 (en) 1991-12-12 1993-06-24 Gilead Sciences, Inc. Nuclease stable and binding competent oligomers and methods for their use
WO1994001446A2 (en) * 1992-07-09 1994-01-20 Beckman Instruments, Inc. Derivatized organic solid support for nucleic acid synthesis
FR2707296B1 (fr) * 1993-07-09 1995-09-29 Genset Sa Procédé de synthèse d'acides nucléiques sur support solide et composés utiles notamment comme support solide dans ledit procédé.
AU692816B2 (en) * 1993-07-19 1998-06-18 Gen-Probe Incorporated Oligonucleotide screening assay
US5739309A (en) * 1993-07-19 1998-04-14 Gen-Probe Incorporated Enhancement of oligonucleotide inhibition of protein production, cell proliferation and / or multiplication of infectious disease pathogens
WO1995003407A2 (en) * 1993-07-19 1995-02-02 Gen-Probe Incorporated Oligonucleotides with activity against human immunodeficiency virus
US5733781A (en) 1994-07-19 1998-03-31 Gen-Probe Incorporated Oligonucleotides and methods for inhibiting propagation of human immunodeficiency virus
ES2150103T3 (es) * 1995-01-19 2000-11-16 Gen Probe Inc Oligonucleotidos de amplificacion de acido nucleico y sondas para borrelia asociados con la enfermedad de lyme.
US5747470A (en) * 1995-06-07 1998-05-05 Gen-Probe Incorporated Method for inhibiting cellular proliferation using antisense oligonucleotides to gp130 mRNA
US5731148A (en) * 1995-06-07 1998-03-24 Gen-Probe Incorporated Adduct protection assay
US5747252A (en) 1995-06-07 1998-05-05 Gen-Probe Incorporated Nucleic acid probes and amplification oligonucleotides for Neisseria species
US5674995A (en) * 1995-06-07 1997-10-07 Gen-Probe Incorporated Oligonucleotides specific for cytokine signal transducer gp130 mRNA
US5716846A (en) * 1995-06-07 1998-02-10 Gen-Probe Incorporated Method for inhibiting cellular proliferation using antisense oligonucleotides to interleukin-6 receptor mRNA
US6025133A (en) * 1996-12-30 2000-02-15 Gen-Probe Incorporated Promoter-sequestered oligonucleoside and method of use
US6146833A (en) * 1997-02-11 2000-11-14 Beckman Coulter, Inc. Polymeric reagents for immobilizing biopolymers
US6932943B1 (en) 2001-01-26 2005-08-23 Third Wave Technologies Nucleic acid synthesizers
US20030072689A1 (en) * 2001-08-15 2003-04-17 Third Wave Technologies, Inc. Polymer synthesizer
US7435390B2 (en) * 2001-01-26 2008-10-14 Third Wave Technologies, Inc. Nucleic acid synthesizers
EP2765202B1 (en) 2006-08-01 2017-02-01 Gen-Probe Incorporated Methods of nonspecific target capture of nucleic acids
WO2009124150A2 (en) 2008-04-01 2009-10-08 Biosearch Technologies, Inc. Stabilized nucleic acid dark quencher-fluorophore probes
US10913767B2 (en) * 2010-04-22 2021-02-09 Alnylam Pharmaceuticals, Inc. Oligonucleotides comprising acyclic and abasic nucleosides and analogs
EP2885312B1 (en) * 2012-08-15 2025-09-03 Ionis Pharmaceuticals, Inc. Method of preparing oligomeric compounds using modified capping protocols
MY180166A (en) 2014-05-09 2020-11-24 Biosearch Tech Inc Cosmic quenchers
US10618926B2 (en) 2015-04-02 2020-04-14 Merck Sharp & Dohme Process for making phosphoramidate protected nucleoside compounds
MY181693A (en) 2015-04-15 2021-01-01 Biosearch Tech Inc Dual quencher probes
US20200165599A1 (en) 2017-05-11 2020-05-28 Gen-Probe Incorporated Compositions and Methods for Isolating Target Nucleic Acids
US12522817B2 (en) 2019-11-14 2026-01-13 Gen-Probe Incorporated Compositions and methods for capturing target nucleic acids

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4458066A (en) * 1980-02-29 1984-07-03 University Patents, Inc. Process for preparing polynucleotides
US4500707A (en) * 1980-02-29 1985-02-19 University Patents, Inc. Nucleosides useful in the preparation of polynucleotides
US4469863A (en) * 1980-11-12 1984-09-04 Ts O Paul O P Nonionic nucleic acid alkyl and aryl phosphonates and processes for manufacture and use thereof
US4668777A (en) * 1981-03-27 1987-05-26 University Patents, Inc. Phosphoramidite nucleoside compounds
US4415732A (en) * 1981-03-27 1983-11-15 University Patents, Inc. Phosphoramidite compounds and processes
DE3329892A1 (de) * 1983-08-18 1985-03-07 Köster, Hubert, Prof. Dr., 2000 Hamburg Verfahren zur herstellung von oligonucleotiden
US4923901A (en) * 1987-09-04 1990-05-08 Millipore Corporation Membranes with bound oligonucleotides and peptides

Also Published As

Publication number Publication date
EP0592434A4 (en) 1996-04-24
IE913761A1 (en) 1992-05-22
US5726300A (en) 1998-03-10
WO1992007864A1 (en) 1992-05-14
DE69130331T2 (de) 1999-03-04
AU8875391A (en) 1992-05-26
AU669103B2 (en) 1996-05-30
TW216423B (OSRAM) 1993-11-21
EP0592434A1 (en) 1994-04-20
ES2124231T3 (es) 1999-02-01
IL99844A (en) 1995-07-31
ATE171947T1 (de) 1998-10-15
DE69130331D1 (de) 1998-11-12
EP0592434B1 (en) 1998-10-07
NZ240325A (en) 1993-06-25
CA2094803A1 (en) 1992-04-27
JPH06509542A (ja) 1994-10-27

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