US6146657A
(en)
|
1989-12-22 |
2000-11-14 |
Imarx Pharmaceutical Corp. |
Gas-filled lipid spheres for use in diagnostic and therapeutic applications
|
US5656211A
(en)
|
1989-12-22 |
1997-08-12 |
Imarx Pharmaceutical Corp. |
Apparatus and method for making gas-filled vesicles of optimal size
|
US5922304A
(en)
|
1989-12-22 |
1999-07-13 |
Imarx Pharmaceutical Corp. |
Gaseous precursor filled microspheres as magnetic resonance imaging contrast agents
|
US5469854A
(en)
|
1989-12-22 |
1995-11-28 |
Imarx Pharmaceutical Corp. |
Methods of preparing gas-filled liposomes
|
US5776429A
(en)
|
1989-12-22 |
1998-07-07 |
Imarx Pharmaceutical Corp. |
Method of preparing gas-filled microspheres using a lyophilized lipids
|
US6088613A
(en)
|
1989-12-22 |
2000-07-11 |
Imarx Pharmaceutical Corp. |
Method of magnetic resonance focused surgical and therapeutic ultrasound
|
US6551576B1
(en)
|
1989-12-22 |
2003-04-22 |
Bristol-Myers Squibb Medical Imaging, Inc. |
Container with multi-phase composition for use in diagnostic and therapeutic applications
|
US5585112A
(en)
|
1989-12-22 |
1996-12-17 |
Imarx Pharmaceutical Corp. |
Method of preparing gas and gaseous precursor-filled microspheres
|
US5542935A
(en)
|
1989-12-22 |
1996-08-06 |
Imarx Pharmaceutical Corp. |
Therapeutic delivery systems related applications
|
US6001335A
(en)
|
1989-12-22 |
1999-12-14 |
Imarx Pharmaceutical Corp. |
Contrasting agents for ultrasonic imaging and methods for preparing the same
|
USRE39146E1
(en)
|
1990-04-02 |
2006-06-27 |
Bracco International B.V. |
Long-lasting aqueous dispersions or suspensions of pressure-resistant gas-filled microvesicles and methods for the preparation thereof
|
IN172208B
(no)
*
|
1990-04-02 |
1993-05-01 |
Sint Sa |
|
US6613306B1
(en)
|
1990-04-02 |
2003-09-02 |
Bracco International B.V. |
Ultrasound contrast agents and methods of making and using them
|
US5205290A
(en)
|
1991-04-05 |
1993-04-27 |
Unger Evan C |
Low density microspheres and their use as contrast agents for computed tomography
|
US5874062A
(en)
|
1991-04-05 |
1999-02-23 |
Imarx Pharmaceutical Corp. |
Methods of computed tomography using perfluorocarbon gaseous filled microspheres as contrast agents
|
MX9205298A
(es)
|
1991-09-17 |
1993-05-01 |
Steven Carl Quay |
Medios gaseosos de contraste de ultrasonido y metodo para seleccionar gases para usarse como medios de contraste de ultrasonido
|
CZ286149B6
(cs)
*
|
1991-09-17 |
2000-01-12 |
Sonus Pharmaceuticals, Inc. |
Plynná prostředí pro zvýšení kontrastnosti obrazu, získaného ultrazvukem a způsob výběru plynů pro toto použití
|
US6875420B1
(en)
|
1991-09-17 |
2005-04-05 |
Amersham Health As |
Method of ultrasound imaging
|
US6723303B1
(en)
|
1991-09-17 |
2004-04-20 |
Amersham Health, As |
Ultrasound contrast agents including protein stabilized microspheres of perfluoropropane, perfluorobutane or perfluoropentane
|
US5409688A
(en)
*
|
1991-09-17 |
1995-04-25 |
Sonus Pharmaceuticals, Inc. |
Gaseous ultrasound contrast media
|
IL104084A
(en)
|
1992-01-24 |
1996-09-12 |
Bracco Int Bv |
Sustainable aqueous suspensions of pressure-resistant and gas-filled blisters, their preparation, and contrast agents containing them
|
LV10396B
(en)
*
|
1992-03-06 |
1996-02-20 |
Nycomed Imaging As |
Novel contrast agents
|
US5674468A
(en)
*
|
1992-03-06 |
1997-10-07 |
Nycomed Imaging As |
Contrast agents comprising gas-containing or gas-generating polymer microparticles or microballoons
|
IL108416A
(en)
|
1993-01-25 |
1998-10-30 |
Sonus Pharma Inc |
Colloids with phase difference as contrast ultrasound agents
|
NZ262237A
(en)
*
|
1993-01-25 |
1997-06-24 |
Sonus Pharma Inc |
Ultrasound contrast agents comprising phase shift colloids having a boiling point below the body temperature of the animal it is used in
|
US5558855A
(en)
*
|
1993-01-25 |
1996-09-24 |
Sonus Pharmaceuticals |
Phase shift colloids as ultrasound contrast agents
|
US5798091A
(en)
*
|
1993-07-30 |
1998-08-25 |
Alliance Pharmaceutical Corp. |
Stabilized gas emulsion containing phospholipid for ultrasound contrast enhancement
|
PT711179E
(pt)
*
|
1993-07-30 |
2005-03-31 |
Imcor Pharmaceutical Company |
Composicoes de microbolhas estabilizadas para ultra-som
|
ES2192572T3
(es)
|
1993-12-15 |
2003-10-16 |
Bracco Research Sa |
Medios de contraste de ultrasonidos, agentes de contraste que contienen los medios, y metodo.
|
DE4406474A1
(de)
|
1994-02-23 |
1995-08-24 |
Schering Ag |
Gas enthaltende Mikropartikel, diese enthaltende Mittel, deren Verwendung in der Ultraschalldiagnostik, sowie Verfahren zur Herstellung der Partikel und Mittel
|
US5540909A
(en)
*
|
1994-09-28 |
1996-07-30 |
Alliance Pharmaceutical Corp. |
Harmonic ultrasound imaging with microbubbles
|
US6743779B1
(en)
|
1994-11-29 |
2004-06-01 |
Imarx Pharmaceutical Corp. |
Methods for delivering compounds into a cell
|
US5830430A
(en)
|
1995-02-21 |
1998-11-03 |
Imarx Pharmaceutical Corp. |
Cationic lipids and the use thereof
|
US5558092A
(en)
*
|
1995-06-06 |
1996-09-24 |
Imarx Pharmaceutical Corp. |
Methods and apparatus for performing diagnostic and therapeutic ultrasound simultaneously
|
US5997898A
(en)
|
1995-06-06 |
1999-12-07 |
Imarx Pharmaceutical Corp. |
Stabilized compositions of fluorinated amphiphiles for methods of therapeutic delivery
|
US5804162A
(en)
*
|
1995-06-07 |
1998-09-08 |
Alliance Pharmaceutical Corp. |
Gas emulsions stabilized with fluorinated ethers having low Ostwald coefficients
|
US6033645A
(en)
|
1996-06-19 |
2000-03-07 |
Unger; Evan C. |
Methods for diagnostic imaging by regulating the administration rate of a contrast agent
|
US6521211B1
(en)
|
1995-06-07 |
2003-02-18 |
Bristol-Myers Squibb Medical Imaging, Inc. |
Methods of imaging and treatment with targeted compositions
|
US6231834B1
(en)
|
1995-06-07 |
2001-05-15 |
Imarx Pharmaceutical Corp. |
Methods for ultrasound imaging involving the use of a contrast agent and multiple images and processing of same
|
US6139819A
(en)
|
1995-06-07 |
2000-10-31 |
Imarx Pharmaceutical Corp. |
Targeted contrast agents for diagnostic and therapeutic use
|
DE19602930A1
(de)
*
|
1996-01-18 |
1997-07-24 |
Schering Ag |
Poröse Matrices aus niedermolekularen Substanzen zur Genierung stabiler Gasblasensuspensionen, deren Verwendung als Ultraschallkontrastmittel sowie Verfahren zu deren Herstellung
|
US5611344A
(en)
*
|
1996-03-05 |
1997-03-18 |
Acusphere, Inc. |
Microencapsulated fluorinated gases for use as imaging agents
|
CZ281298A3
(cs)
*
|
1996-03-05 |
1999-01-13 |
Acusphere, Inc. |
Fluorované plyny v mikrokapslích jako zobrazující činidla pro ultrazvukové vyšetření
|
WO1997040679A1
(en)
|
1996-05-01 |
1997-11-06 |
Imarx Pharmaceutical Corp. |
Methods for delivering compounds into a cell
|
US5874064A
(en)
*
|
1996-05-24 |
1999-02-23 |
Massachusetts Institute Of Technology |
Aerodynamically light particles for pulmonary drug delivery
|
US5985309A
(en)
*
|
1996-05-24 |
1999-11-16 |
Massachusetts Institute Of Technology |
Preparation of particles for inhalation
|
US6652837B1
(en)
|
1996-05-24 |
2003-11-25 |
Massachusetts Institute Of Technology |
Preparation of novel particles for inhalation
|
US6414139B1
(en)
|
1996-09-03 |
2002-07-02 |
Imarx Therapeutics, Inc. |
Silicon amphiphilic compounds and the use thereof
|
ES2189974T3
(es)
|
1996-09-11 |
2003-07-16 |
Imarx Pharmaceutical Corp |
Procedimientos mejorados para la obtencion de imagenes de diagnostico usando un agente de contraste y un vasodilatador.
|
US5846517A
(en)
|
1996-09-11 |
1998-12-08 |
Imarx Pharmaceutical Corp. |
Methods for diagnostic imaging using a renal contrast agent and a vasodilator
|
US6143276A
(en)
|
1997-03-21 |
2000-11-07 |
Imarx Pharmaceutical Corp. |
Methods for delivering bioactive agents to regions of elevated temperatures
|
US6090800A
(en)
|
1997-05-06 |
2000-07-18 |
Imarx Pharmaceutical Corp. |
Lipid soluble steroid prodrugs
|
US6537246B1
(en)
|
1997-06-18 |
2003-03-25 |
Imarx Therapeutics, Inc. |
Oxygen delivery agents and uses for the same
|
US6416740B1
(en)
|
1997-05-13 |
2002-07-09 |
Bristol-Myers Squibb Medical Imaging, Inc. |
Acoustically active drug delivery systems
|
US6045777A
(en)
*
|
1997-06-30 |
2000-04-04 |
Acusphere, Inc. |
Method for enhancing the echogenicity and decreasing the attenuation of microencapsulated gases
|
US6548047B1
(en)
|
1997-09-15 |
2003-04-15 |
Bristol-Myers Squibb Medical Imaging, Inc. |
Thermal preactivation of gaseous precursor filled compositions
|
US6123923A
(en)
|
1997-12-18 |
2000-09-26 |
Imarx Pharmaceutical Corp. |
Optoacoustic contrast agents and methods for their use
|
US20010003580A1
(en)
|
1998-01-14 |
2001-06-14 |
Poh K. Hui |
Preparation of a lipid blend and a phospholipid suspension containing the lipid blend
|
US6048736A
(en)
*
|
1998-04-29 |
2000-04-11 |
Kosak; Kenneth M. |
Cyclodextrin polymers for carrying and releasing drugs
|
FR2780901B1
(fr)
*
|
1998-07-09 |
2000-09-29 |
Coletica |
Particules, en particulier micro- ou nanoparticules de monosaccharides et oligosaccharides reticules, leurs procedes de preparation et compositions cosmetiques, pharmaceutiques ou alimentaires en contenant
|
US6426145B1
(en)
|
1999-05-20 |
2002-07-30 |
Scimed Life Systems, Inc. |
Radiopaque compositions for visualization of medical devices
|
US6572840B1
(en)
|
1999-07-28 |
2003-06-03 |
Bristol-Myers Squibb Pharma Company |
Stable microbubbles comprised of a perfluoropropane encapsulated lipid moiety for use as an ultrasound contrast agent
|
EP2286843A3
(en)
|
2000-06-02 |
2011-08-03 |
Bracco Suisse SA |
Compounds for targeting endothelial cells
|
EP1387637B1
(en)
*
|
2001-04-06 |
2007-10-31 |
Bracco Research S.A. |
Apparatus for measuring local physical parameters in a fluid filled cavity
|
US7211240B2
(en)
|
2002-03-01 |
2007-05-01 |
Bracco International B.V. |
Multivalent constructs for therapeutic and diagnostic applications
|
EP1587944A4
(en)
|
2002-03-01 |
2007-03-21 |
Dyax Corp |
KDR AND VEGF / KDR BINDING PEPTIDES AND THEIR USE FOR DIAGNOSTIC AND THERAPEUTIC PURPOSES
|
ES2506142T3
(es)
|
2002-03-01 |
2014-10-13 |
Dyax Corp. |
Péptidos de unión a KDR y a VEGF/KDR y su uso en diagnóstico
|
US7261876B2
(en)
|
2002-03-01 |
2007-08-28 |
Bracco International Bv |
Multivalent constructs for therapeutic and diagnostic applications
|
US7794693B2
(en)
|
2002-03-01 |
2010-09-14 |
Bracco International B.V. |
Targeting vector-phospholipid conjugates
|
US8623822B2
(en)
|
2002-03-01 |
2014-01-07 |
Bracco Suisse Sa |
KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy
|
US7462366B2
(en)
|
2002-03-29 |
2008-12-09 |
Boston Scientific Scimed, Inc. |
Drug delivery particle
|
WO2003105917A2
(en)
|
2002-06-12 |
2003-12-24 |
Scimed Life Systems, Inc. |
Bulking agents
|
US7842377B2
(en)
|
2003-08-08 |
2010-11-30 |
Boston Scientific Scimed, Inc. |
Porous polymeric particle comprising polyvinyl alcohol and having interior to surface porosity-gradient
|
US8012454B2
(en)
|
2002-08-30 |
2011-09-06 |
Boston Scientific Scimed, Inc. |
Embolization
|
US7883490B2
(en)
|
2002-10-23 |
2011-02-08 |
Boston Scientific Scimed, Inc. |
Mixing and delivery of therapeutic compositions
|
DK2284180T3
(en)
|
2003-03-03 |
2015-12-21 |
Dyax Corp |
Uses of peptides that specifically bind to the HGF receptor (cMET)
|
US7976823B2
(en)
|
2003-08-29 |
2011-07-12 |
Boston Scientific Scimed, Inc. |
Ferromagnetic particles and methods
|
WO2005041897A2
(en)
|
2003-10-31 |
2005-05-12 |
Point Biomedical Corporation |
Reconstitutable microsphere compositions useful as ultrasonic contrast agents
|
US7736671B2
(en)
|
2004-03-02 |
2010-06-15 |
Boston Scientific Scimed, Inc. |
Embolization
|
US8173176B2
(en)
|
2004-03-30 |
2012-05-08 |
Boston Scientific Scimed, Inc. |
Embolization
|
US7311861B2
(en)
|
2004-06-01 |
2007-12-25 |
Boston Scientific Scimed, Inc. |
Embolization
|
US8012457B2
(en)
|
2004-06-04 |
2011-09-06 |
Acusphere, Inc. |
Ultrasound contrast agent dosage formulation
|
US8425550B2
(en)
|
2004-12-01 |
2013-04-23 |
Boston Scientific Scimed, Inc. |
Embolic coils
|
US7727555B2
(en)
|
2005-03-02 |
2010-06-01 |
Boston Scientific Scimed, Inc. |
Particles
|
US7858183B2
(en)
|
2005-03-02 |
2010-12-28 |
Boston Scientific Scimed, Inc. |
Particles
|
US7963287B2
(en)
|
2005-04-28 |
2011-06-21 |
Boston Scientific Scimed, Inc. |
Tissue-treatment methods
|
US8123693B2
(en)
|
2005-06-20 |
2012-02-28 |
Conceptus, Inc. |
Methods and devices for determining lumen occlusion
|
US9463426B2
(en)
|
2005-06-24 |
2016-10-11 |
Boston Scientific Scimed, Inc. |
Methods and systems for coating particles
|
US8007509B2
(en)
|
2005-10-12 |
2011-08-30 |
Boston Scientific Scimed, Inc. |
Coil assemblies, components and methods
|
US8152839B2
(en)
|
2005-12-19 |
2012-04-10 |
Boston Scientific Scimed, Inc. |
Embolic coils
|
US8101197B2
(en)
|
2005-12-19 |
2012-01-24 |
Stryker Corporation |
Forming coils
|
US7947368B2
(en)
|
2005-12-21 |
2011-05-24 |
Boston Scientific Scimed, Inc. |
Block copolymer particles
|
US8414927B2
(en)
|
2006-11-03 |
2013-04-09 |
Boston Scientific Scimed, Inc. |
Cross-linked polymer particles
|
US8585616B2
(en)
|
2009-10-09 |
2013-11-19 |
Conceptus, Inc. |
Methods and apparatus for determining fallopian tube occlusion
|
WO2012136813A2
(en)
|
2011-04-07 |
2012-10-11 |
Universitetet I Oslo |
Agents for medical radar diagnosis
|
JP6420817B2
(ja)
|
2013-03-15 |
2018-11-07 |
バイオコンパティブルズ ユーケー リミテッド |
結像可能な塞栓性微小球
|
GB2521997A
(en)
|
2013-09-06 |
2015-07-15 |
Biocompatibles Uk Ltd |
Radiopaque polymers
|
GB2519738A
(en)
|
2013-09-06 |
2015-05-06 |
Biocompatibles Uk Ltd |
Radiopaque polymers
|
CN112716895A
(zh)
*
|
2020-12-18 |
2021-04-30 |
济南大学 |
基于苯丁酸修饰的普朗尼克f127的穿心莲内酯载药胶束及其制备
|
CN114808179B
(zh)
*
|
2022-03-30 |
2023-06-16 |
华南理工大学 |
一种可控弛豫时间的复合材料及其制备方法和应用
|