DK0571253T3 - Benzimidazolderivater med antidiabetisk og antiblodpladekoagulerende virkning - Google Patents

Benzimidazolderivater med antidiabetisk og antiblodpladekoagulerende virkning

Info

Publication number
DK0571253T3
DK0571253T3 DK93401239T DK93401239T DK0571253T3 DK 0571253 T3 DK0571253 T3 DK 0571253T3 DK 93401239 T DK93401239 T DK 93401239T DK 93401239 T DK93401239 T DK 93401239T DK 0571253 T3 DK0571253 T3 DK 0571253T3
Authority
DK
Denmark
Prior art keywords
antidiabetic
benzimidazole derivatives
coagulant effect
platelet coagulant
platelet
Prior art date
Application number
DK93401239T
Other languages
Danish (da)
English (en)
Inventor
Vera Alekseevna Anisimova
Margarita Valentinov Levchenko
Tatyana Borisovna Korochina
Alexander Alexeyevich Spasov
Sergei Gennadyevich Kovalev
Galina Petrovna Dudchenko
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9206036A external-priority patent/FR2691462B1/fr
Priority claimed from FR9209488A external-priority patent/FR2694293B1/fr
Application filed by Adir filed Critical Adir
Application granted granted Critical
Publication of DK0571253T3 publication Critical patent/DK0571253T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK93401239T 1992-05-19 1993-05-14 Benzimidazolderivater med antidiabetisk og antiblodpladekoagulerende virkning DK0571253T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9206036A FR2691462B1 (fr) 1992-05-19 1992-05-19 Nouveaux derives du benzimidazole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
FR9209488A FR2694293B1 (fr) 1992-07-31 1992-07-31 Nouveau dérivé du benzimidazole, son procédé de préparation et les compositions pharmaceutiques qui le contiennent.

Publications (1)

Publication Number Publication Date
DK0571253T3 true DK0571253T3 (da) 1999-07-19

Family

ID=26229468

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93401239T DK0571253T3 (da) 1992-05-19 1993-05-14 Benzimidazolderivater med antidiabetisk og antiblodpladekoagulerende virkning

Country Status (10)

Country Link
US (2) US5623073A (de)
EP (1) EP0571253B1 (de)
JP (1) JP2506263B2 (de)
AT (1) ATE172975T1 (de)
AU (1) AU656466B2 (de)
CA (1) CA2096475A1 (de)
DE (1) DE69321875T2 (de)
DK (1) DK0571253T3 (de)
ES (1) ES2126636T3 (de)
NZ (1) NZ247643A (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2362337C (en) 1993-06-25 2005-08-02 Merrell Pharmaceuticals Inc. Novel intermediates for the preparation of antihistaminic 4-diphenylmethyl/diphenylmethoxy piperidine derivatives
US6147216A (en) * 1993-06-25 2000-11-14 Merrell Pharmaceuticals Inc. Intermediates useful for the preparation of antihistaminic piperidine derivatives
AUPN236595A0 (en) 1995-04-11 1995-05-11 Rescare Limited Monitoring of apneic arousals
FR2765223B1 (fr) * 1997-06-25 1999-08-27 Adir Nouveaux derives tricycliques du benzimidazole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US6683094B2 (en) 1998-07-02 2004-01-27 Aventis Pharmaceuticals Inc. Antihistaminic piperidine derivatives and intermediates for the preparation thereof
US6930197B2 (en) 1998-07-02 2005-08-16 Aventis Pharmaceuticals Inc. Antihistaminic piperidine derivatives and intermediates for the preparation thereof
JP3398121B2 (ja) 2000-05-16 2003-04-21 株式会社堀場製作所 粒度分布測定装置
EE200300342A (et) * 2001-01-26 2003-12-15 Bristol-Myers Squibb Company Imidasolüüli derivaadid kui kortikotropiini vabastava faktori inhibiitorid, nende saamismeetodid ning kasutamine
DE602005007215D1 (de) * 2004-05-14 2008-07-10 Cleveland Clinic Foundation Kleinmolekülige hemmer für mrp1 und andere multiarzneimitteltransporter
WO2007109120A2 (en) 2006-03-17 2007-09-27 Ambit Biosciences Corporation Imidazolothiazole compounds for the treatment of disease
PL2201018T3 (pl) 2007-09-19 2016-11-30 STAŁE POSTACIE ZAWIERAJĄCE N-(5-TERT-BUTYLOIZOKSAZOL-3-ILO)-N'-{4--[7-(2-MORFOLIN-4-YLOETOKSY)IMIDAZO[2,1-b][1,3]BENZOTIAZOL-2-ILO]FENYLO}MOCZNIK, ICH KOMPOZYCJE ORAZ ICH ZASTOSOWANIA
US20090247520A1 (en) * 2008-03-27 2009-10-01 The Burnham Institute For Medical Research INHIBITORS OF ANTIGEN RECEPTOR-INDUCED NF-kappa B ACTIVATION
GB0808952D0 (en) * 2008-05-16 2008-06-25 Shire Llc Substituted quinazolines
GB0808968D0 (en) * 2008-05-16 2008-06-25 Shire Llc Substitute quinazolines
GB0808947D0 (en) * 2008-05-16 2008-06-25 Shire Llc Substituted quinazolines
GB0808967D0 (en) * 2008-05-16 2008-06-25 Shire Llc Substitute quinazolines
TWI567079B (zh) * 2011-07-15 2017-01-21 健生醫藥公司 作為伽瑪分泌酶調節劑之新穎的經取代的吲哚衍生物
US10137211B2 (en) 2015-08-28 2018-11-27 Chdi Foundation, Inc. Probes for imaging Huntingtin protein
CN108250202B (zh) * 2018-01-15 2019-10-25 陕西师范大学 2,3-二取代苯并咪唑并[1,2-a]嘧啶类化合物及其制备方法和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3732243A (en) * 1970-06-23 1973-05-08 Sankyo Co 2-(p-bromophenyl)-9-dimethyl-amino-propyl-9h-imidazo(1,2-a)benzimidazole
GB1476949A (en) * 1974-11-20 1977-06-16 Wyeth John & Brother Ltd Imidazo-1,2-a-benzimidazole and pyrimido-1,2-a-benzimidazole derivatives their preparation and their pharmaceutical compositions
US5008282A (en) * 1988-12-28 1991-04-16 Kotobuki Seiyaku Co. Ltd. Cyclic guanidine derivatives, anti-ulceratives and methods of manufacturing the same

Also Published As

Publication number Publication date
ES2126636T3 (es) 1999-04-01
US5623073A (en) 1997-04-22
US5639756A (en) 1997-06-17
NZ247643A (en) 1995-07-26
EP0571253B1 (de) 1998-11-04
EP0571253A1 (de) 1993-11-24
AU656466B2 (en) 1995-02-02
DE69321875T2 (de) 1999-06-17
CA2096475A1 (fr) 1993-11-20
AU3860893A (en) 1993-11-25
ATE172975T1 (de) 1998-11-15
JP2506263B2 (ja) 1996-06-12
JPH0687859A (ja) 1994-03-29
DE69321875D1 (de) 1998-12-10

Similar Documents

Publication Publication Date Title
DK0571253T3 (da) Benzimidazolderivater med antidiabetisk og antiblodpladekoagulerende virkning
IS4185A (is) Hliðstæð aðferð til framleiðslu fenýlsúlfonylamino-pýrimidines afleiða
ATE18902T1 (de) Aminosaeurederivate und ihre therapeutischen verwendungen.
FI914928A (fi) Hydroximetyl (metylencyklopentyl) puriner och -pyrimidiner.
TR199501253A2 (tr) Amino(tio) eter türevleri.
NO179834C (no) Substituerte cykloheksanderivater og anvendelse av forbindelsene for fremstilling av legemidler
DK0459256T3 (da) Oxazolidiononer
NZ240575A (en) N-benzoylproline derivatives and pharmaceutical compositions
DE69115526D1 (de) 2,4-Pyrimidindionderivate und diese enthaltende Arzneimittel
IT1270975B (it) Composti piperidin-triazinici atti all'impiego come stabilizzanti allaluce, al calore e alla ossidazione per materiali organici
NO306116B1 (no) Ny benzotiadiazinforbindelse og farmasöytiske sammensetninger
FI892675A0 (fi) 2,6-dihalogenpyridin-3 -karboxylsyraderivat och deras framstaellning.
DK0617035T3 (da) Hetero-tricyclisk-substituerede phenyl-cyclohexan-carboxylsyrederivater.
DE69413112T2 (de) 5-HT3 Pyrrolopyrazinderivate
ATE123025T1 (de) 2-amino-n-(((4-(aminocarbonyl)pyrimidin-2- yl>amino>alkyl>-pyrimidin-4- carbonsäureamidderivate, ihre herstellung und ihre anwendung in der therapeutica.
DK0552631T3 (da) Alfa-Aryl-alfa-hydroxy-beta-imidazolinyl-propionsyreamider
ATE111099T1 (de) Ergolinderivate.
ES2061182T3 (es) 2-fluoroneplanocina a y su fabricacion.