DE69321875D1 - Benzimidezolderivate mit antidiabetischer und Anti-Plättchenklumpungswirkung - Google Patents

Benzimidezolderivate mit antidiabetischer und Anti-Plättchenklumpungswirkung

Info

Publication number
DE69321875D1
DE69321875D1 DE69321875T DE69321875T DE69321875D1 DE 69321875 D1 DE69321875 D1 DE 69321875D1 DE 69321875 T DE69321875 T DE 69321875T DE 69321875 T DE69321875 T DE 69321875T DE 69321875 D1 DE69321875 D1 DE 69321875D1
Authority
DE
Germany
Prior art keywords
derivatives
benzimidezole
diabetic
platelet clumping
clumping effect
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69321875T
Other languages
English (en)
Other versions
DE69321875T2 (de
Inventor
Vera Alekseevna Anisimova
Margarita Valentinov Levchenko
Tatyana Borisovna Korochina
Alexander Alexeyevich Spasov
Sergei Gennadyevich Kovalev
Galina Petrovna Dudchenko
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ADIR SARL
Original Assignee
ADIR SARL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9206036A external-priority patent/FR2691462B1/fr
Priority claimed from FR9209488A external-priority patent/FR2694293B1/fr
Application filed by ADIR SARL filed Critical ADIR SARL
Publication of DE69321875D1 publication Critical patent/DE69321875D1/de
Application granted granted Critical
Publication of DE69321875T2 publication Critical patent/DE69321875T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE69321875T 1992-05-19 1993-05-14 Benzimidezolderivate mit antidiabetischer und Anti-Plättchenklumpungswirkung Expired - Fee Related DE69321875T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9206036A FR2691462B1 (fr) 1992-05-19 1992-05-19 Nouveaux derives du benzimidazole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
FR9209488A FR2694293B1 (fr) 1992-07-31 1992-07-31 Nouveau dérivé du benzimidazole, son procédé de préparation et les compositions pharmaceutiques qui le contiennent.

Publications (2)

Publication Number Publication Date
DE69321875D1 true DE69321875D1 (de) 1998-12-10
DE69321875T2 DE69321875T2 (de) 1999-06-17

Family

ID=26229468

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69321875T Expired - Fee Related DE69321875T2 (de) 1992-05-19 1993-05-14 Benzimidezolderivate mit antidiabetischer und Anti-Plättchenklumpungswirkung

Country Status (10)

Country Link
US (2) US5623073A (de)
EP (1) EP0571253B1 (de)
JP (1) JP2506263B2 (de)
AT (1) ATE172975T1 (de)
AU (1) AU656466B2 (de)
CA (1) CA2096475A1 (de)
DE (1) DE69321875T2 (de)
DK (1) DK0571253T3 (de)
ES (1) ES2126636T3 (de)
NZ (1) NZ247643A (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6147216A (en) * 1993-06-25 2000-11-14 Merrell Pharmaceuticals Inc. Intermediates useful for the preparation of antihistaminic piperidine derivatives
ATE230395T1 (de) 1993-06-25 2003-01-15 Merrell Pharma Inc Neue zwischenprodukte für die herstellung von antihistaminschen 4- diphenylmethyl/diphenylmethoxypiperidin-derivat n
AUPN236595A0 (en) 1995-04-11 1995-05-11 Rescare Limited Monitoring of apneic arousals
FR2765223B1 (fr) * 1997-06-25 1999-08-27 Adir Nouveaux derives tricycliques du benzimidazole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US6683094B2 (en) 1998-07-02 2004-01-27 Aventis Pharmaceuticals Inc. Antihistaminic piperidine derivatives and intermediates for the preparation thereof
US6689898B2 (en) 1998-07-02 2004-02-10 Aventis Pharmaceuticals Inc. Antihistaminic piperidine derivatives and intermediates for the preparation thereof
JP3398121B2 (ja) 2000-05-16 2003-04-21 株式会社堀場製作所 粒度分布測定装置
IL156813A0 (en) * 2001-01-26 2004-02-08 Bristol Myers Squibb Co Imidazolyl derivatives and pharmaceutical compositions containing the same
ATE396725T1 (de) * 2004-05-14 2008-06-15 Cleveland Clinic Foundation Kleinmolekülige hemmer für mrp1 und andere multiarzneimitteltransporter
KR101549364B1 (ko) * 2006-03-17 2015-09-01 암비트 바이오사이언시즈 코포레이션 질환 치료용 이미다졸로티아졸 화합물
KR20150104231A (ko) 2007-09-19 2015-09-14 암비트 바이오사이언시즈 코포레이션 Ｎ-(5-ｔｅｒｔ-부틸-이속사졸-3-일)-Ｎ''-[4-[7-(2-모르폴린-4-일-에톡시)이미다조[2,1-Ｂ][1,3]벤조티아졸-2-일]페닐]우레아를 포함하는 고체 형태, 그의 조성물 및 그의 용도
WO2009120874A2 (en) * 2008-03-27 2009-10-01 Burnham Institute For Medical Research INHIBITORS OF ANTIGEN RECEPTOR-INDUCED NF-кB ACTIVATION
GB0808947D0 (en) * 2008-05-16 2008-06-25 Shire Llc Substituted quinazolines
GB0808968D0 (en) * 2008-05-16 2008-06-25 Shire Llc Substitute quinazolines
GB0808952D0 (en) * 2008-05-16 2008-06-25 Shire Llc Substituted quinazolines
GB0808967D0 (en) * 2008-05-16 2008-06-25 Shire Llc Substitute quinazolines
EA023045B1 (ru) * 2011-07-15 2016-04-29 Янссен Фармасьютикалз, Инк. Новые замещенные производные индола в качестве модуляторов гамма-секретазы
HRP20211156T1 (hr) * 2015-08-28 2021-12-24 Chdi Foundation, Inc. Kontrastna sredstva za slikovnu dijagnostiku huntingtin proteina
CN108250202B (zh) * 2018-01-15 2019-10-25 陕西师范大学 2,3-二取代苯并咪唑并[1,2-a]嘧啶类化合物及其制备方法和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3732243A (en) * 1970-06-23 1973-05-08 Sankyo Co 2-(p-bromophenyl)-9-dimethyl-amino-propyl-9h-imidazo(1,2-a)benzimidazole
GB1476949A (en) * 1974-11-20 1977-06-16 Wyeth John & Brother Ltd Imidazo-1,2-a-benzimidazole and pyrimido-1,2-a-benzimidazole derivatives their preparation and their pharmaceutical compositions
US5008282A (en) * 1988-12-28 1991-04-16 Kotobuki Seiyaku Co. Ltd. Cyclic guanidine derivatives, anti-ulceratives and methods of manufacturing the same

Also Published As

Publication number Publication date
EP0571253B1 (de) 1998-11-04
DE69321875T2 (de) 1999-06-17
EP0571253A1 (de) 1993-11-24
NZ247643A (en) 1995-07-26
ES2126636T3 (es) 1999-04-01
DK0571253T3 (da) 1999-07-19
ATE172975T1 (de) 1998-11-15
US5639756A (en) 1997-06-17
JP2506263B2 (ja) 1996-06-12
CA2096475A1 (fr) 1993-11-20
JPH0687859A (ja) 1994-03-29
AU3860893A (en) 1993-11-25
AU656466B2 (en) 1995-02-02
US5623073A (en) 1997-04-22

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee