DK0570764T3 - Asymmetrisk hydrogenering - Google Patents

Asymmetrisk hydrogenering

Info

Publication number
DK0570764T3
DK0570764T3 DK93107272T DK93107272T DK0570764T3 DK 0570764 T3 DK0570764 T3 DK 0570764T3 DK 93107272 T DK93107272 T DK 93107272T DK 93107272 T DK93107272 T DK 93107272T DK 0570764 T3 DK0570764 T3 DK 0570764T3
Authority
DK
Denmark
Prior art keywords
compounds
asymmetric hydrogenation
image
general formula
novel
Prior art date
Application number
DK93107272T
Other languages
English (en)
Inventor
Francois Montavon
Emil Albin Broger
Yvo Crameri
Marquard Imfeld
Erich Widmer
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of DK0570764T3 publication Critical patent/DK0570764T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/06—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/04—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/04—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having less than three double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/02—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Catalysts (AREA)
DK93107272T 1992-05-18 1993-05-05 Asymmetrisk hydrogenering DK0570764T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH158292 1992-05-18
CH72993 1993-03-11

Publications (1)

Publication Number Publication Date
DK0570764T3 true DK0570764T3 (da) 2001-11-05

Family

ID=25685509

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93107272T DK0570764T3 (da) 1992-05-18 1993-05-05 Asymmetrisk hydrogenering

Country Status (7)

Country Link
US (1) US5750690A (da)
EP (1) EP0570764B1 (da)
JP (1) JP3526310B2 (da)
AT (1) ATE203242T1 (da)
DE (1) DE59310189D1 (da)
DK (1) DK0570764T3 (da)
ES (1) ES2164056T3 (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2777888B1 (fr) 1998-04-27 2004-07-16 Hoechst Marion Roussel Inc Nouveaux derives de l'acide (3,4,7,8,9,10-hexahydro-6,10- dioxo-6h-pyridazino[1,2-a][1,2]diazepine-1-carboxylique, leur procede de preparation et leur application a la preparation de medicaments
US6222039B1 (en) 1998-07-13 2001-04-24 Hoffman-La Roche Inc. Process for the preparation of chiral lactones
EP0974590A1 (en) * 1998-07-13 2000-01-26 F. Hoffmann-La Roche Ag Process for the preparation of chiral lactones by asymetrical hydrogenation
US7253169B2 (en) 1999-11-12 2007-08-07 Gliamed, Inc. Aza compounds, pharmaceutical compositions and methods of use
US6417189B1 (en) 1999-11-12 2002-07-09 Gpi Nil Holdings, Inc. AZA compounds, pharmaceutical compositions and methods of use
NZ520998A (en) 2000-05-04 2004-11-26 Vertex Pharma Asymmetric synthesis of piperazic acid and derivatives thereof
US7262303B2 (en) * 2003-09-29 2007-08-28 Hoffman-La Roche Inc. Process for the production of chiral propionic acid derivatives
EP2221299A3 (en) 2009-02-11 2010-11-03 Dr. Reddy's Laboratories Ltd. Preparation of cilazapril intermediates
JP5546781B2 (ja) * 2009-03-10 2014-07-09 日本化学工業株式会社 ２，２’−ビス（ジアルキルホスフィノ）ビフェニル化合物及びその製造方法並びに該化合物を配位子とする金属錯体

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4331818A (en) * 1980-03-19 1982-05-25 The Procter & Gamble Company Chiral phospine ligand
GB2128984B (en) * 1982-05-12 1985-05-22 Hoffmann La Roche Diaza-bicyclic compounds
DK350383A (da) * 1982-08-27 1984-02-28 Hoffmann La Roche Phosphorforbindelser
EP0272787B1 (en) * 1986-11-14 1992-05-06 Takasago International Corporation Catalytic production of optically active carboxylic acid
ATE128140T1 (de) * 1989-05-18 1995-10-15 Hoffmann La Roche Phosphorverbindungen.
JPH0692427B2 (ja) * 1989-07-11 1994-11-16 高砂香料工業株式会社 ２，２’―ビス（ジシクロヘキシルホスフィノ）―６，６’―ジメチル―１，１’―ビフェニルを配位子とする錯体，およびその錯体を用いた有機カルボン酸とそのエステルの製造方法
ATE179981T1 (de) * 1992-01-31 1999-05-15 Hoffmann La Roche Diphosphinliganden

Also Published As

Publication number Publication date
ES2164056T3 (es) 2002-02-16
EP0570764A3 (en) 1994-06-29
JPH0632780A (ja) 1994-02-08
EP0570764B1 (de) 2001-07-18
EP0570764A2 (de) 1993-11-24
ATE203242T1 (de) 2001-08-15
US5750690A (en) 1998-05-12
JP3526310B2 (ja) 2004-05-10
DE59310189D1 (de) 2001-08-23

Similar Documents

Publication Publication Date Title
NL300396I1 (nl) Nieuwe derivaten met naftalinestructuren, werkwijze voor de bereiding ervan en de farmaceutische preparaten die deze bevatten
ATE121739T1 (de) Discodermolideverbindungen, diese enthaltende zubereitungen, verfahren zu ihrer herstellung und deren verwendung.
ATE203242T1 (de) Asymmetrische hydrierung
ATE90676T1 (de) Dioxyalkylenaryl-dihydropyridine zwischenprodukte zu ihrer herstellung, verfahren zu ihrer herstellung und ihre verwendung.
ATE25983T1 (de) Sulfonierte chirale phosphine, ihre herstellung und ihre verwendung in asymmetrischer katalyse.
DE59206900D1 (de) Diphosphonsaurederivate als zwischenprodukte zur herstellung von diphosphinliganden
MX9300875A (es) Procedimiento para la preparacion de compuestos azabiciclicos.
DE68922478D1 (de) Pyrazoloisoquinoline-Derivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen.
DE59303616D1 (de) Verfahren zur Herstellung von Isoprenderivaten
ATE18549T1 (de) 1-carboxyalkanoylindolin-2-carbonsaeure-ester, verfahren zu ihrer herstellung, pharmazeutische praeparate enthaltend diese verbindungen, sowie ihre therapeutische verwendung.
ES493599A0 (es) Un procedimiento para la preparacion de derivados de azeti din-2-ona.
DE59310246D1 (de) Asymmetrische Hydrierung
CA2038025A1 (en) Optically active alkylenedioxybenzene derivatives and their use in therapy
DK0643052T3 (da) Fremgangsmåde til enantioselektiv hydrogenering af 2H-pyran-2-on-derivater
DE59009525D1 (de) Herstellung von Isochinolinderivaten.
ES2138605T3 (es) Hidrogenacion asimetrica.
MX9306421A (es) Derivados de amidas y procedimiento para su preparacion.
DE59107308D1 (de) Asymmetrische Hydrierung
EP0382506A3 (en) Optically active diastereomer salts of tetrahydro-2-furoic acid
ATE18556T1 (de) Phenylalkyloxirancarbonsaeuren, verfahren zu ihrer herstellung, ihre anwendung und sie enthaltende arzneimittel.
ATE66463T1 (de) 1,4-cyclohexandiamine, verfahren zu ihrer herstellung und ihre verwendung als fungizide.
ES2139670T3 (es) Derivados de 1-fenilpirrolidona con actividad optica y preparacion de los mismos.
ATE100817T1 (de) Herstellung von optisch aktiven 2-oxoimidazolidin-derivaten.
ATE164573T1 (de) Verfahren zur herstellung von 1-unsubstituierten 3-aminopyrrolen
EP0370974A3 (en) Process for preparing heterocyclic derivatives

Legal Events

Date Code Title Description
A0 Application filed
AHS Application shelved for other reasons than non-payment