DK0559752T3 - Optiske isomerer af 7-[3-1-(dialkylmethyl-1-amino)-1-pyrrolidinyl]-quinoloner og -naphthyridoner som antibakterielle stoffe - Google Patents
Optiske isomerer af 7-[3-1-(dialkylmethyl-1-amino)-1-pyrrolidinyl]-quinoloner og -naphthyridoner som antibakterielle stoffeInfo
- Publication number
- DK0559752T3 DK0559752T3 DK92900619T DK92900619T DK0559752T3 DK 0559752 T3 DK0559752 T3 DK 0559752T3 DK 92900619 T DK92900619 T DK 92900619T DK 92900619 T DK92900619 T DK 92900619T DK 0559752 T3 DK0559752 T3 DK 0559752T3
- Authority
- DK
- Denmark
- Prior art keywords
- naphthyridones
- quinolones
- dialkylmethyl
- pyrrolidinyl
- amino
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
- C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/621,101 US5072001A (en) | 1990-11-30 | 1990-11-30 | Certain optically active substituted 3-pyrraidine acetic acid derivatives useful as intermediates |
| US07/730,362 US5157128A (en) | 1990-11-30 | 1991-07-15 | Certain optically active substituted α,α-dialkyl-pyrrolidine-3-methamines useful as intermediates |
| PCT/US1991/008422 WO1992009597A1 (en) | 1990-11-30 | 1991-11-12 | Optical isomers of 7-[3-(1,1-dialkylmethyl-1-amino-1-pyrrolidinyl]-quinolones and naphthyridones as antibacterial agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0559752T3 true DK0559752T3 (da) | 1998-09-21 |
Family
ID=27088852
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK92900619T DK0559752T3 (da) | 1990-11-30 | 1991-11-12 | Optiske isomerer af 7-[3-1-(dialkylmethyl-1-amino)-1-pyrrolidinyl]-quinoloner og -naphthyridoner som antibakterielle stoffe |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US5157128A (xx) |
| EP (1) | EP0559752B1 (xx) |
| JP (2) | JP2582515B2 (xx) |
| AT (1) | ATE162789T1 (xx) |
| AU (1) | AU643107B2 (xx) |
| CA (2) | CA2362944C (xx) |
| DE (1) | DE69128838T2 (xx) |
| DK (1) | DK0559752T3 (xx) |
| ES (1) | ES2113938T3 (xx) |
| GR (1) | GR3026428T3 (xx) |
| IE (1) | IE61722B1 (xx) |
| NZ (2) | NZ240783A (xx) |
| PT (1) | PT99658B (xx) |
| WO (1) | WO1992009597A1 (xx) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU649893B1 (en) * | 1991-11-25 | 1994-06-02 | Warner-Lambert Company | Antibacterial agents |
| DE69131428T2 (de) * | 1990-11-30 | 2000-01-05 | Warner-Lambert Co., Ann Arbor | Individuelle stereoisomere von 7-[3-(aminoalkyl)-1-pyrrolidinyl]-quinolone und naphthyridone als antibakterielle wirkstoffe |
| US5221676A (en) * | 1992-02-06 | 1993-06-22 | Warner-Lambert Company | 7-substituted quinolones and naphthyridones as antibacterial agents |
| FR2687146B1 (fr) * | 1992-02-12 | 1994-04-01 | Adir Cie | Nouveaux derives de pyrrolidine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
| US6140510A (en) * | 1993-05-06 | 2000-10-31 | Pharmacia & Upjohn Company | Optically active 3-(1-(carbamoyl))alkyl-2-oxo-pyrrolidines and optically active 3-(1-(alkylamido))alkyl-2-oxo-pyrrolidines |
| EP0697015A1 (en) * | 1993-05-06 | 1996-02-21 | PHARMACIA & UPJOHN COMPANY | Optically active 3-(1-(alkylamino))alkyl pyrrolidines |
| US5347017A (en) * | 1993-07-07 | 1994-09-13 | Warner-Lambert Company | Process for chiral 3-(1-amino-1,1-bisalkylmethyl)-1-substituted-pyrrolidines |
| IL132982A0 (en) * | 1997-05-21 | 2001-03-19 | Daiichi Seiyaku Co | Cis-disubstituted aminocycloalkyl-pyrrolidine derivatives |
| ATE297912T1 (de) * | 1998-11-24 | 2005-07-15 | Daiichi Seiyaku Co | Cycloalkylsubstituierte aminomethylpyrrolidin- derivate |
| ATE268329T1 (de) * | 1999-03-10 | 2004-06-15 | Daiichi Seiyaku Co | Aminomethylpyrrolidin-derivate mit aromatischen substituenten |
| TWI530510B (zh) | 2012-11-01 | 2016-04-21 | 旭化成化學股份有限公司 | 聚異氰酸酯組成物及異氰酸酯聚合物組成物 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4665079A (en) * | 1984-02-17 | 1987-05-12 | Warner-Lambert Company | Antibacterial agents |
| EP0207420B1 (en) * | 1985-06-26 | 1992-05-06 | Daiichi Pharmaceutical Co., Ltd. | Pyridonecarboxylic acid derivatives |
| JPH0723369B2 (ja) * | 1986-12-27 | 1995-03-15 | 第一製薬株式会社 | ピリドンカルボン酸誘導体 |
| US4780468A (en) * | 1987-08-07 | 1988-10-25 | Warner-Lambert Company | 8-trifluoromethyl quinolones as antibacterial agents |
| CA2012681A1 (en) * | 1989-03-31 | 1990-09-30 | Masayasu Okuhira | Quinolone derivatives, preparation processes thereof, and antibacterial agents containing the same |
-
1991
- 1991-07-15 US US07/730,362 patent/US5157128A/en not_active Expired - Lifetime
- 1991-11-12 AT AT92900619T patent/ATE162789T1/de not_active IP Right Cessation
- 1991-11-12 CA CA002362944A patent/CA2362944C/en not_active Expired - Fee Related
- 1991-11-12 ES ES92900619T patent/ES2113938T3/es not_active Expired - Lifetime
- 1991-11-12 WO PCT/US1991/008422 patent/WO1992009597A1/en active IP Right Grant
- 1991-11-12 EP EP92900619A patent/EP0559752B1/en not_active Expired - Lifetime
- 1991-11-12 AU AU90856/91A patent/AU643107B2/en not_active Ceased
- 1991-11-12 DK DK92900619T patent/DK0559752T3/da active
- 1991-11-12 CA CA002095361A patent/CA2095361C/en not_active Expired - Fee Related
- 1991-11-12 JP JP4501923A patent/JP2582515B2/ja not_active Expired - Fee Related
- 1991-11-12 DE DE69128838T patent/DE69128838T2/de not_active Expired - Fee Related
- 1991-11-28 NZ NZ240783A patent/NZ240783A/en not_active IP Right Cessation
- 1991-11-29 IE IE416191A patent/IE61722B1/en not_active IP Right Cessation
- 1991-11-29 PT PT99658A patent/PT99658B/pt not_active IP Right Cessation
-
1992
- 1992-06-29 US US07/906,260 patent/US5278317A/en not_active Expired - Lifetime
-
1993
- 1993-11-26 NZ NZ250300A patent/NZ250300A/xx not_active IP Right Cessation
-
1996
- 1996-07-16 JP JP8185801A patent/JP2817907B2/ja not_active Expired - Fee Related
-
1998
- 1998-03-20 GR GR980400618T patent/GR3026428T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE69128838D1 (de) | 1998-03-05 |
| JPH06503089A (ja) | 1994-04-07 |
| JPH09100266A (ja) | 1997-04-15 |
| NZ250300A (en) | 1995-01-27 |
| ES2113938T3 (es) | 1998-05-16 |
| US5278317A (en) | 1994-01-11 |
| JP2817907B2 (ja) | 1998-10-30 |
| IE914161A1 (en) | 1992-06-03 |
| EP0559752B1 (en) | 1998-01-28 |
| NZ240783A (en) | 1994-12-22 |
| CA2095361A1 (en) | 1992-05-31 |
| AU9085691A (en) | 1992-06-25 |
| US5157128A (en) | 1992-10-20 |
| AU643107B2 (en) | 1993-11-04 |
| PT99658A (pt) | 1992-10-30 |
| CA2095361C (en) | 2002-10-08 |
| DE69128838T2 (de) | 1998-06-25 |
| PT99658B (pt) | 1999-05-31 |
| JP2582515B2 (ja) | 1997-02-19 |
| CA2362944C (en) | 2003-03-18 |
| GR3026428T3 (en) | 1998-06-30 |
| EP0559752A1 (en) | 1993-09-15 |
| IE61722B1 (en) | 1994-11-30 |
| WO1992009597A1 (en) | 1992-06-11 |
| ATE162789T1 (de) | 1998-02-15 |
| CA2362944A1 (en) | 1992-06-11 |
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