DK0540782T3 - Anvendelse af polyisoprenylpyrophosphatanaloger til inhibering af proteinisoprenylering - Google Patents

Anvendelse af polyisoprenylpyrophosphatanaloger til inhibering af proteinisoprenylering

Info

Publication number
DK0540782T3
DK0540782T3 DK91202616T DK91202616T DK0540782T3 DK 0540782 T3 DK0540782 T3 DK 0540782T3 DK 91202616 T DK91202616 T DK 91202616T DK 91202616 T DK91202616 T DK 91202616T DK 0540782 T3 DK0540782 T3 DK 0540782T3
Authority
DK
Denmark
Prior art keywords
independently represent
isoprenylation
sulphur
polyisoprenylpyrophosphate
analogues
Prior art date
Application number
DK91202616T
Other languages
English (en)
Inventor
Louis H Cohen
Boom Jacobus H Van
Der Marel Gijsbert A Van
Adrianus P R M Valentijn
Jacobus H Van Boom
Gijsbert A Van Der Marel
Original Assignee
Tno
Univ Leiden
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tno, Univ Leiden filed Critical Tno
Application granted granted Critical
Publication of DK0540782T3 publication Critical patent/DK0540782T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK91202616T 1991-10-07 1991-10-07 Anvendelse af polyisoprenylpyrophosphatanaloger til inhibering af proteinisoprenylering DK0540782T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP91202616A EP0540782B1 (en) 1991-10-07 1991-10-07 Use of analogues of polyisoprenyl pyrophosphate for inhibiting protein isoprenylation

Publications (1)

Publication Number Publication Date
DK0540782T3 true DK0540782T3 (da) 1999-11-01

Family

ID=8207934

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91202616T DK0540782T3 (da) 1991-10-07 1991-10-07 Anvendelse af polyisoprenylpyrophosphatanaloger til inhibering af proteinisoprenylering

Country Status (7)

Country Link
EP (1) EP0540782B1 (da)
JP (1) JP3518611B2 (da)
AT (1) ATE179607T1 (da)
DE (1) DE69131199T2 (da)
DK (1) DK0540782T3 (da)
ES (1) ES2133278T3 (da)
GR (1) GR3030795T3 (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2267494B (en) * 1992-06-02 1995-09-20 Ciba Geigy Ag Trisamidodithionodiphosphates
US5883066A (en) * 1993-06-28 1999-03-16 The Procter & Gamble Company Liquid detergent compositions containing cellulase and amine
US5840918A (en) * 1994-03-15 1998-11-24 Eisai Co., Ltd. Isoprenyl transferase inhibitors
US5574025A (en) * 1994-10-26 1996-11-12 Merck & Co., Inc. Inhibitors of prenyl-protein transferases
JP2001158799A (ja) 1999-09-28 2001-06-12 Rijksuniv Leiden プレニル化ピロリン酸消費酵素の新規な阻害剤
EP1090909A1 (en) * 1999-09-28 2001-04-11 Rijksuniversiteit Leiden Novel inhibitors of prenylated pyrophosphate consuming enzymes
AU1226001A (en) * 1999-11-09 2001-06-06 Alcon Universal Limited Phospholipids of hydroxyeicosatetraenoic acid-like derivatives

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4871721A (en) * 1988-01-11 1989-10-03 E. R. Squibb & Sons, Inc. Phosphorus-containing squalene synthetase inhibitors
JP2714402B2 (ja) * 1988-07-13 1998-02-16 日清製粉株式会社 癌転移抑制剤
EP0356866A3 (en) * 1988-08-29 1991-03-27 E.R. SQUIBB & SONS, INC. Phosphorus-containing squalene synthetase inhibitors and method
US5025003A (en) * 1989-09-18 1991-06-18 E. R. Squibb & Sons, Inc. Isoprenoid phosphinylformic acid squalene synthetase inhibitors

Also Published As

Publication number Publication date
EP0540782A1 (en) 1993-05-12
ES2133278T3 (es) 1999-09-16
JP3518611B2 (ja) 2004-04-12
GR3030795T3 (en) 1999-11-30
ATE179607T1 (de) 1999-05-15
JPH07188028A (ja) 1995-07-25
DE69131199D1 (de) 1999-06-10
DE69131199T2 (de) 1999-08-26
EP0540782B1 (en) 1999-05-06

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