ATE179607T1 - Verwendung von polyisoprenyl pyrophosphate analogen zur hemmung des proteinisoprenylations - Google Patents

Verwendung von polyisoprenyl pyrophosphate analogen zur hemmung des proteinisoprenylations

Info

Publication number
ATE179607T1
ATE179607T1 AT91202616T AT91202616T ATE179607T1 AT E179607 T1 ATE179607 T1 AT E179607T1 AT 91202616 T AT91202616 T AT 91202616T AT 91202616 T AT91202616 T AT 91202616T AT E179607 T1 ATE179607 T1 AT E179607T1
Authority
AT
Austria
Prior art keywords
independently represent
isoprenylation
pyrophosphate analogue
polyisoprenyl
polyisoprenyl pyrophosphate
Prior art date
Application number
AT91202616T
Other languages
English (en)
Inventor
Louis H Cohen
Boom Jacobus H Van
Der Marel Gijsbert A Van
Adrianus P R M Valentijn
Original Assignee
Tno
Univ Leiden
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tno, Univ Leiden filed Critical Tno
Application granted granted Critical
Publication of ATE179607T1 publication Critical patent/ATE179607T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT91202616T 1991-10-07 1991-10-07 Verwendung von polyisoprenyl pyrophosphate analogen zur hemmung des proteinisoprenylations ATE179607T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP91202616A EP0540782B1 (de) 1991-10-07 1991-10-07 Verwendung von Polyisoprenyl pyrophosphate Analogen zur Hemmung des Proteinisoprenylations

Publications (1)

Publication Number Publication Date
ATE179607T1 true ATE179607T1 (de) 1999-05-15

Family

ID=8207934

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91202616T ATE179607T1 (de) 1991-10-07 1991-10-07 Verwendung von polyisoprenyl pyrophosphate analogen zur hemmung des proteinisoprenylations

Country Status (7)

Country Link
EP (1) EP0540782B1 (de)
JP (1) JP3518611B2 (de)
AT (1) ATE179607T1 (de)
DE (1) DE69131199T2 (de)
DK (1) DK0540782T3 (de)
ES (1) ES2133278T3 (de)
GR (1) GR3030795T3 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2267494B (en) * 1992-06-02 1995-09-20 Ciba Geigy Ag Trisamidodithionodiphosphates
US5883066A (en) * 1993-06-28 1999-03-16 The Procter & Gamble Company Liquid detergent compositions containing cellulase and amine
CA2185441A1 (en) * 1994-03-15 1995-09-21 Michael D. Lewis Isoprenyl transferase inhibitors
US5574025A (en) * 1994-10-26 1996-11-12 Merck & Co., Inc. Inhibitors of prenyl-protein transferases
JP2001158799A (ja) 1999-09-28 2001-06-12 Rijksuniv Leiden プレニル化ピロリン酸消費酵素の新規な阻害剤
EP1090909A1 (de) * 1999-09-28 2001-04-11 Rijksuniversiteit Leiden Hemmer für Enzyme, die Prenylpyrophosphate umsetzen
US6353032B1 (en) * 1999-11-09 2002-03-05 Alcon Universal Ltd. Phospholipids of hydroxyeicosatetraenoic acid-like derivatives and methods of use

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4871721A (en) * 1988-01-11 1989-10-03 E. R. Squibb & Sons, Inc. Phosphorus-containing squalene synthetase inhibitors
JP2714402B2 (ja) * 1988-07-13 1998-02-16 日清製粉株式会社 癌転移抑制剤
EP0356866A3 (de) * 1988-08-29 1991-03-27 E.R. SQUIBB & SONS, INC. Phosphor enthaltende Squalen-Synthetase-Inhibitoren und Verfahren
US5025003A (en) * 1989-09-18 1991-06-18 E. R. Squibb & Sons, Inc. Isoprenoid phosphinylformic acid squalene synthetase inhibitors

Also Published As

Publication number Publication date
DE69131199T2 (de) 1999-08-26
JPH07188028A (ja) 1995-07-25
EP0540782B1 (de) 1999-05-06
EP0540782A1 (de) 1993-05-12
DK0540782T3 (da) 1999-11-01
ES2133278T3 (es) 1999-09-16
GR3030795T3 (en) 1999-11-30
DE69131199D1 (de) 1999-06-10
JP3518611B2 (ja) 2004-04-12

Similar Documents

Publication Publication Date Title
DE69324859D1 (de) Verwendung von Lipid-gebundener Glykoaminoglykanen zur Behandlung der rheumatoider Arthritis
ATE178055T1 (de) Hiv-proteaseinhibitoren und ihre verwendung zur behandlung von aids
DE69026980D1 (de) Schwefel enthaltende kondensierte Pyrimidinderivate, ihre Herstellung und Verwendung
IL175398A0 (en) Steroidal compounds and pharmaceutical compositions containing them for treating oxidative stress and inflammation
DK1252133T3 (da) Farmaceutiske forbindelser
DE3888568D1 (de) Menschliche peptidische Hemmungsstoffe von Leukozyten-Elastase (HLE).
ATE137954T1 (de) Zahnmedizinische/medizinische zusammensetzung für restaurations-/prothesenzwecke und ihre verwendung
TW222638B (de)
ATE179607T1 (de) Verwendung von polyisoprenyl pyrophosphate analogen zur hemmung des proteinisoprenylations
DE69224524D1 (de) Antimikrobielle breitspektrum-verbindungen und verfahren zu deren verwendung
HU913883D0 (en) N-(iodo-propargyl-oxi-carbonyl)amino acid esthers of anti-microbial effect
HU9303680D0 (en) Inhibitors of hiv protease useful for the treatment of aids
HUP0100470A2 (hu) Oxazolidinonszármazékok és ilyen vegyületeket tartalmazó gyógyászati készítmények
AU589431B2 (en) Nitrogen containing heterocyclic oxo and thio compounds useful as pesticides
FI941052A0 (fi) Kollageenin indusoiman verihiutaleaggregaation inhibiittori
DE69816244D1 (de) Verwendung von 2-Aryl-3-aroylbenzo(b)thiophene zur Behandlung des Oestrogenenthaltungssyndroms
NO173991C (no) Analogifremgangsmaate til fremstilling av terapeutisk aktive 1,2,5-ditiazocin-derivater
GB8801289D0 (en) Oxadiazole compounds their preparation & their use as pesticides
NO934058D0 (no) Arylkondensert- og hetarylkondensert-2,4-diazepiner og -2,4-diazociner med antiarrytmisk aktivitet
AU4706489A (en) Oxadiazol-azabicycl compounds and their pharmaceutical use

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee