DK0538422T3 - Hidtil ukendt anvendelse af diphenylbutyl-piperazincarboxamider til behandling af stofmisbrugslidelser - Google Patents

Hidtil ukendt anvendelse af diphenylbutyl-piperazincarboxamider til behandling af stofmisbrugslidelser

Info

Publication number
DK0538422T3
DK0538422T3 DK92907159T DK92907159T DK0538422T3 DK 0538422 T3 DK0538422 T3 DK 0538422T3 DK 92907159 T DK92907159 T DK 92907159T DK 92907159 T DK92907159 T DK 92907159T DK 0538422 T3 DK0538422 T3 DK 0538422T3
Authority
DK
Denmark
Prior art keywords
diphenylbutyl
treatment
substance abuse
new use
piperazine
Prior art date
Application number
DK92907159T
Other languages
Danish (da)
English (en)
Inventor
Anders Bjoerk
Erik Christensson
Original Assignee
Pharmacia & Upjohn Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia & Upjohn Ab filed Critical Pharmacia & Upjohn Ab
Application granted granted Critical
Publication of DK0538422T3 publication Critical patent/DK0538422T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/215—Radicals derived from nitrogen analogues of carbonic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Addiction (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Toxicology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK92907159T 1991-03-22 1992-03-23 Hidtil ukendt anvendelse af diphenylbutyl-piperazincarboxamider til behandling af stofmisbrugslidelser DK0538422T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9100860A SE9100860D0 (sv) 1991-03-22 1991-03-22 New use
PCT/SE1992/000182 WO1992016211A1 (en) 1991-03-22 1992-03-23 New use of diphenylbutyl-piperazinecarboxamides in the treatment of substance disorders

Publications (1)

Publication Number Publication Date
DK0538422T3 true DK0538422T3 (da) 2001-05-07

Family

ID=20382242

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92907159T DK0538422T3 (da) 1991-03-22 1992-03-23 Hidtil ukendt anvendelse af diphenylbutyl-piperazincarboxamider til behandling af stofmisbrugslidelser

Country Status (24)

Country Link
US (2) US5434156A (pt)
EP (1) EP0538422B1 (pt)
JP (1) JP3221611B2 (pt)
KR (1) KR100196674B1 (pt)
AT (1) ATE199057T1 (pt)
AU (1) AU653797B2 (pt)
BG (1) BG61829B1 (pt)
BR (1) BR9204969A (pt)
CA (1) CA2083505C (pt)
CZ (1) CZ282222B6 (pt)
DE (1) DE69231680T2 (pt)
DK (1) DK0538422T3 (pt)
EE (1) EE02973B1 (pt)
ES (1) ES2154261T3 (pt)
GR (1) GR3035805T3 (pt)
HU (2) HU9203632D0 (pt)
IE (1) IE920920A1 (pt)
NO (1) NO301311B1 (pt)
PT (1) PT100279B (pt)
RO (1) RO109702B1 (pt)
RU (1) RU2095062C1 (pt)
SE (1) SE9100860D0 (pt)
SK (1) SK279237B6 (pt)
WO (1) WO1992016211A1 (pt)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9100860D0 (sv) * 1991-03-22 1991-03-22 Kabi Pharmacia Ab New use
SE9201239D0 (sv) * 1992-04-21 1992-04-21 Kabi Pharmacia Ab Agents for treating substance abuse disorders
JP3571114B2 (ja) * 1995-07-11 2004-09-29 ポーラ化成工業株式会社 麻薬拮抗剤
US6265393B1 (en) 1998-08-07 2001-07-24 Heinrichs William Leroy Prevention of endometriosis signs or symptons
US6090780A (en) * 1999-04-07 2000-07-18 Chandon Prasad Histidyl-proline diketopiperazine and method of use
USRE39921E1 (en) 1999-10-07 2007-11-13 Smithkline Beecham Corporation Chemical compounds
GB9923748D0 (en) 1999-10-07 1999-12-08 Glaxo Group Ltd Chemical compounds
GB0025354D0 (en) 2000-10-17 2000-11-29 Glaxo Group Ltd Chemical compounds
BR0206549A (pt) * 2001-01-17 2004-02-25 Hythiam Inc Uso de flumazenil na produção de uma droga para o tratamento de dependência de álcool
US20050192271A1 (en) * 2003-07-15 2005-09-01 Hythiam, Inc. Use of selective chloride channel modulators to treat alcohol and/or stimulant substance abuse
US7183410B2 (en) * 2001-08-02 2007-02-27 Bidachem S.P.A. Stable polymorph of flibanserin
US20030060475A1 (en) * 2001-08-10 2003-03-27 Boehringer Ingelheim Pharma Kg Method of using flibanserin for neuroprotection
US10675280B2 (en) 2001-10-20 2020-06-09 Sprout Pharmaceuticals, Inc. Treating sexual desire disorders with flibanserin
UA78974C2 (en) * 2001-10-20 2007-05-10 Boehringer Ingelheim Pharma Use of flibanserin for treating disorders of sexual desire
GB0203020D0 (en) 2002-02-08 2002-03-27 Glaxo Group Ltd Chemical compounds
US7482365B2 (en) 2002-02-08 2009-01-27 Glaxo Group Limited Piperidylcarboxamide derivatives and their use in the treatment of tachykinin-mediated diseases
GB0203022D0 (en) 2002-02-08 2002-03-27 Glaxo Group Ltd Chemical compounds
US20050239798A1 (en) * 2004-04-22 2005-10-27 Boehringer Ingelheim Pharmaceuticals, Inc. Method for the treatment of premenstrual and other female sexual disorders
AU2005235422B2 (en) * 2004-04-22 2011-08-11 Boehringer Ingelheim International Gmbh New pharmaceutical compositions for the treatment of sexual disorders II
US20060025420A1 (en) * 2004-07-30 2006-02-02 Boehringer Ingelheimn International GmbH Pharmaceutical compositions for the treatment of female sexual disorders
EP1789048A1 (en) * 2004-09-03 2007-05-30 Boehringer Ingelheim International GmbH Method for the treatment of attention deficit hyperactivity disorder
JP2008531714A (ja) * 2005-03-04 2008-08-14 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 不安障害の治療用及び／又は予防用の医薬組成物
WO2006096439A2 (en) * 2005-03-04 2006-09-14 Boehringer Ingelheim International Gmbh Pharmaceutical compositions for the treatment and/or prevention of schizophrenia and related diseases
JP2008538741A (ja) * 2005-03-04 2008-11-06 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 鬱病の治療用及び／又は予防用の医薬組成物
CA2608249A1 (en) * 2005-05-06 2006-11-16 Boehringer Ingelheim International Gmbh Method for the treatment of drug abuse with flibanserin
JP2008540672A (ja) * 2005-05-19 2008-11-20 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 病状に起因する性的機能不全の治療方法
US20060264511A1 (en) * 2005-05-19 2006-11-23 Boehringer Ingelheim International Gmbh Method for the treatment of drug-induced sexual dysfunction
CA2617546C (en) 2005-08-03 2014-07-15 Boehringer Ingelheim International Gmbh Use of flibanserin in the treatment of obesity
EP1945214A1 (en) * 2005-10-29 2008-07-23 Boehringer Ingelheim International GmbH Benzimidazolone derivatives for the treatment of premenstrual and other female sexual disorders
US20070123540A1 (en) * 2005-10-29 2007-05-31 Angelo Ceci Sexual desire enhancing medicaments comprising benzimidazolone derivatives
US20070105869A1 (en) * 2005-11-08 2007-05-10 Stephane Pollentier Use of flibanserin for the treatment of pre-menopausal sexual desire disorders
EP2021006B1 (en) * 2006-05-09 2015-08-12 Sprout Pharmaceuticals, Inc. Use of flibanserin for the treatment of post-menopausal sexual desire disorders
JP2009541443A (ja) 2006-06-30 2009-11-26 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 尿失禁及び関連疾患の治療のためのフリバンセリン
WO2008006838A1 (en) * 2006-07-14 2008-01-17 Boehringer Ingelheim International Gmbh Use of flibanserin for the treatment of sexual disorders in females
CL2007002214A1 (es) * 2006-08-14 2008-03-07 Boehringer Ingelheim Int Composicion farmaceutica en la forma de comprimido, donde al menos la longitud del comprimido en el estado anterior de la aplicacion es al menos 7/12 del diametro pilorico del paciente y despues de ingerirlo en estado alimentado, la longitud del comp
CA2660476C (en) 2006-08-14 2015-11-17 Boehringer Ingelheim International Gmbh Formulations of flibanserin and method for manufacturing the same
JP5220746B2 (ja) * 2006-08-25 2013-06-26 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 制御放出システム及びその製造方法
CL2008002693A1 (es) * 2007-09-12 2009-10-16 Boehringer Ingelheim Int Uso de flibanserina para el tratamiento de sintomas vasomotores seleccionados de sofocos, sudores nocturnos, cambios de estado de animo e irritabilidad

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO154582C (no) * 1978-10-20 1986-11-05 Ferrosan Ab Analogifremgangsmaate for fremstilling av terapeutisk aktive difenyl-dibutylpiperazinkarboksamider.
SE9100860D0 (sv) * 1991-03-22 1991-03-22 Kabi Pharmacia Ab New use

Also Published As

Publication number Publication date
AU1428092A (en) 1992-10-21
NO301311B1 (no) 1997-10-13
KR100196674B1 (ko) 1999-06-15
SK344992A3 (en) 1995-11-08
CZ344992A3 (en) 1994-02-16
RU2095062C1 (ru) 1997-11-10
NO924502D0 (no) 1992-11-23
GR3035805T3 (en) 2001-07-31
CZ282222B6 (cs) 1997-06-11
CA2083505A1 (en) 1992-09-23
BG61829B1 (bg) 1998-07-31
WO1992016211A1 (en) 1992-10-01
DE69231680D1 (de) 2001-03-15
JPH05507731A (ja) 1993-11-04
EE02973B1 (et) 1997-04-15
DE69231680T2 (de) 2001-06-07
ES2154261T3 (es) 2001-04-01
EP0538422A1 (en) 1993-04-28
IE920920A1 (en) 1992-09-23
SE9100860D0 (sv) 1991-03-22
HUT64696A (en) 1994-02-28
EP0538422B1 (en) 2001-02-07
SK279237B6 (sk) 1998-08-05
BR9204969A (pt) 1993-07-27
KR930700108A (ko) 1993-03-13
PT100279B (pt) 1999-06-30
US5618817A (en) 1997-04-08
BG97108A (bg) 1994-03-24
AU653797B2 (en) 1994-10-13
CA2083505C (en) 2003-06-10
HU217833B (hu) 2000-04-28
JP3221611B2 (ja) 2001-10-22
HU9203632D0 (en) 1993-03-29
PT100279A (pt) 1993-07-30
RO109702B1 (ro) 1995-05-30
US5434156A (en) 1995-07-18
NO924502L (no) 1992-11-23
ATE199057T1 (de) 2001-02-15

Similar Documents

Publication Publication Date Title
DK0538422T3 (da) Hidtil ukendt anvendelse af diphenylbutyl-piperazincarboxamider til behandling af stofmisbrugslidelser
BG97678A (en) Beta -carotene and/or vitamin e therapy for inhibition of major vascular events
KR930702022A (ko) 인슐린의 경구 투여에 의한 타잎 1 당뇨병의 치료 또는 예방법
IL113566A0 (en) Use of certain methanebisphosphonic acid derivatives to prevent prosthesis loosening and prosthesis migration
ATE226436T1 (de) Neue verwendung von dexmedetomidin
DE69617729D1 (de) Verwendung von antimineralcorticoidverbindungen gegen das drogenentzugssyndrom
ATE74271T1 (de) Ketonderivate als arzneimittel zur behandlung oder vorbeugung des entzugssyndromes.
NO20010627D0 (no) Anvendelse av Gingko Biloba ekstrakter for fremstilling av et medikament for behandling av amyotrofisk lateral sclerose
NZ320355A (en) Use of 1-(2-naphth-2-ylethyl)-4-(3-trifluoromethylphenyl)-1,2,3,6- tetrahydropyridine for preparing drugs for treating amyotrophic lateral sclerosis
DK0637242T3 (da) Midler til behandling af stofmisbrugslidelser
YU39598A (sh) Upotreba duloksetina i njegova farmaceutska smeša
ATE157010T1 (de) Amylin oder amylinanaloga enthaltende zusammensetzung, welche auch wahlweise insulin enthält, zur behandlung von anorexie und verwandten zuständen
NO982463L (no) Anvendelse av en kombinasjon av pentoksyfyllin og type I-interferoner til behandling av multippel sklerose
NZ332484A (en) use of pyridyl and pyrimidyl substituted piperazine derivatives for treating substance abuse disorders
FR2673105B1 (fr) Nouvelles compositions pharmaceutiques, notamment pour le traitement des colopathies fonctionnelles, et procedes de preparation de compositions et de medicaments, notamment pour le traitement de ces affections.
KR940011006A (ko) 황금추출물을 유효성분으로 하는 치주질환예방 및 치료제 조성물
KR960021043A (ko) 스코폴레틴을 포함하는 b형 간염 치료제
KR940003550A (ko) 노인성 치매 예방 및 치료방법