DK0519053T3 - Nucleinsyreamplifikation med DNA-afhængig RNA-polymeraseaktivitet hos RNA-replicaser - Google Patents

Nucleinsyreamplifikation med DNA-afhængig RNA-polymeraseaktivitet hos RNA-replicaser

Info

Publication number
DK0519053T3
DK0519053T3 DK92903684T DK92903684T DK0519053T3 DK 0519053 T3 DK0519053 T3 DK 0519053T3 DK 92903684 T DK92903684 T DK 92903684T DK 92903684 T DK92903684 T DK 92903684T DK 0519053 T3 DK0519053 T3 DK 0519053T3
Authority
DK
Denmark
Prior art keywords
dna
rna
nucleic acid
acid amplification
polymerase activity
Prior art date
Application number
DK92903684T
Other languages
English (en)
Inventor
Randall L Dimond
Steven J Ekenberg
James R Hartnett
Geoffrey R Hudson
Christopher L Jones
Mark A Maffitt
Richard A Martinelli
Leopoldo G Mendoza
Katherine M Miller
John E Monahan
Edward E Pahuski
James W Schumm
Original Assignee
Promega Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Promega Corp filed Critical Promega Corp
Application granted granted Critical
Publication of DK0519053T3 publication Critical patent/DK0519053T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/6867Replicase-based amplification, e.g. using Q-beta replicase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/6853Nucleic acid amplification reactions using modified primers or templates

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
DK92903684T 1990-12-31 1991-12-31 Nucleinsyreamplifikation med DNA-afhængig RNA-polymeraseaktivitet hos RNA-replicaser DK0519053T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US63850890A 1990-12-31 1990-12-31
PCT/US1991/009776 WO1992012261A1 (en) 1990-12-31 1991-12-31 Nucleic acid amplification with dna-dependent rna polymerase activity of rna replicases

Publications (1)

Publication Number Publication Date
DK0519053T3 true DK0519053T3 (da) 1998-07-20

Family

ID=24560333

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92903684T DK0519053T3 (da) 1990-12-31 1991-12-31 Nucleinsyreamplifikation med DNA-afhængig RNA-polymeraseaktivitet hos RNA-replicaser

Country Status (11)

Country Link
US (3) US6090589A (da)
EP (1) EP0519053B1 (da)
JP (1) JP3183510B2 (da)
KR (1) KR100231383B1 (da)
AT (1) ATE159763T1 (da)
AU (2) AU9165091A (da)
CA (1) CA2076750C (da)
DE (1) DE69128077T2 (da)
DK (1) DK0519053T3 (da)
ES (1) ES2108748T3 (da)
WO (1) WO1992012261A1 (da)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993005184A1 (en) * 1991-09-10 1993-03-18 Love Jack D Dna/rna target and signal amplification
EP0682715B1 (en) * 1993-01-15 2006-04-05 The Public Health Research Institute of the City of New York, Inc. Diagnostic assays and kits for detecting rna using rna binary probes and an rna-directed rna ligase
JPH08505531A (ja) * 1993-01-15 1996-06-18 ザ パブリック ヘルス リサーチ インスティチュート オブ ザ シティー オブ ニューヨーク インク Rnaバイナリ・プローブとリボザイムリガーゼを用いたrna検定法
US5876924A (en) * 1994-06-22 1999-03-02 Mount Sinai School Of Medicine Nucleic acid amplification method hybridization signal amplification method (HSAM)
US6593086B2 (en) 1996-05-20 2003-07-15 Mount Sinai School Of Medicine Of New York University Nucleic acid amplification methods
US5942391A (en) 1994-06-22 1999-08-24 Mount Sinai School Of Medicine Nucleic acid amplification method: ramification-extension amplification method (RAM)
USRE38442E1 (en) * 1994-06-22 2004-02-24 Mount Sinai School Of Medicine Nucleic acid amplification method hybridization signal amplification method (HSAM)
FR2723591B1 (fr) * 1994-08-10 1996-09-20 Cis Bio Int Methode d'amplification et/ou de detection d'une sequence d'acide nucleique, reactif de detection et ses applications.
US5753787A (en) * 1995-04-10 1998-05-19 Yale University Nucleic acids encoding ancylostoma secreted protein
US5837466A (en) * 1996-12-16 1998-11-17 Vysis, Inc. Devices and methods for detecting nucleic acid analytes in samples
US6001570A (en) * 1997-02-18 1999-12-14 Invitro Diagnostics, Inc. Compositions, methods, kits and apparatus for determining the presence or absence of target molecules
US6108582A (en) * 1998-07-02 2000-08-22 Intermedics Inc. Cardiac pacemaker lead with extendable/retractable fixation
US20020098485A1 (en) * 2000-02-08 2002-07-25 Morello Ann M. Method for nucleic acid detection via Qbeta replicase
US6562575B1 (en) 2000-06-26 2003-05-13 Epicentre Technologies Corporation Analyte-specific assays based on formation of a replicase substrate
US6949340B2 (en) * 2001-03-28 2005-09-27 Creative Mines Llc Optical phase modulator
GB0111275D0 (en) * 2001-05-09 2001-06-27 Secr Defence Analytical method and kit
US10539561B1 (en) * 2001-08-30 2020-01-21 Customarray, Inc. Enzyme-amplified redox microarray detection process
DE10143106C1 (de) * 2001-09-03 2002-10-10 Artus Ges Fuer Molekularbiolog Vermehrung von Ribonukleinsäuren
US20120077196A9 (en) * 2001-09-03 2012-03-29 Guido Krupp Universal method for selective amplification of mRNAs
US6972173B2 (en) * 2002-03-14 2005-12-06 Intel Corporation Methods to increase nucleotide signals by raman scattering
US6852492B2 (en) * 2001-09-24 2005-02-08 Intel Corporation Nucleic acid sequencing by raman monitoring of uptake of precursors during molecular replication
US7238477B2 (en) * 2001-09-24 2007-07-03 Intel Corporation Methods to increase nucleotide signals by Raman scattering
US20040110208A1 (en) * 2002-03-26 2004-06-10 Selena Chan Methods and device for DNA sequencing using surface enhanced Raman scattering (SERS)
US7476501B2 (en) * 2002-03-26 2009-01-13 Intel Corporation Methods and device for DNA sequencing using surface enhanced raman scattering (SERS)
US20030215816A1 (en) * 2002-05-20 2003-11-20 Narayan Sundararajan Method for sequencing nucleic acids by observing the uptake of nucleotides modified with bulky groups
DE10224200C1 (de) * 2002-05-31 2003-08-21 Artus Ges Fuer Molekularbiolog Vermehrung von Ribonukleinsäuren
DE10240868A1 (de) * 2002-09-04 2004-03-18 Artus Gesellschaft für molekularbiologische Diagnostik und Entwicklung mbH Verbesserte Verfahren zur Synthese von Nukleinsäuren
GB0230238D0 (en) * 2002-12-28 2003-02-05 Fu Guoliang Combined exponential and linear amplification
EP1603674B1 (en) 2003-02-05 2016-01-06 Iquum, Inc. Sample processing
US7745569B2 (en) * 2003-04-07 2010-06-29 The Regents Of The University Of California Amyloid specific binding peptides and detecting abeta peptide
US20060199194A1 (en) * 2003-11-10 2006-09-07 Q-Rna, Inc. Methods of detection using immuno-Q-Amp technology
US20050214805A1 (en) * 2003-11-10 2005-09-29 Q-Rna, Inc. Methods of detection employing immuno-Q-Amp technology
GB0517005D0 (en) * 2005-08-19 2005-09-28 Enigma Diagnostics Ltd Analytical method and kit
US20070065834A1 (en) * 2005-09-19 2007-03-22 Hillis William D Method and sequences for determinate nucleic acid hybridization
US20080003564A1 (en) * 2006-02-14 2008-01-03 Iquum, Inc. Sample processing
WO2012038448A1 (en) * 2010-09-21 2012-03-29 Riboxx Gmbh Method for synthesizing rna using dna template
JP5951755B2 (ja) * 2011-05-04 2016-07-13 エイチティージー モレキュラー ダイアグノスティクス, インコーポレイテッド 定量的ヌクレアーゼプロテクションアッセイ(qNPA)法および定量的ヌクレアーゼプロテクション配列決定(qNPS)法の改善

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1339981C (en) * 1984-05-25 1998-08-04 Fred R. Kramer Replicatable hybridizable recombinant rna probes and methods of using same
US4786600A (en) * 1984-05-25 1988-11-22 The Trustees Of Columbia University In The City Of New York Autocatalytic replication of recombinant RNA
US4957858A (en) * 1986-04-16 1990-09-18 The Salk Instute For Biological Studies Replicative RNA reporter systems
ES8706823A1 (es) 1985-03-28 1987-06-16 Cetus Corp Un procedimiento para detectar la presencia o ausencia de al menos una secuencia especifica de acidos nucleicos en una muestra
IL86724A (en) * 1987-06-19 1995-01-24 Siska Diagnostics Inc Methods and kits for amplification and testing of nucleic acid sequences
JP2939485B2 (ja) * 1988-09-08 1999-08-25 ザ・ソーク・インスチュート・フォーバイオロジカル・スタディーズ 複製rnaに基づく増幅/検出系
CA1339991C (en) 1988-09-08 1998-08-11 The Trustees Of Columbia University Replicative rna-based amplification/detection system
KR0148265B1 (ko) * 1988-12-16 1998-10-15 에프.지이.엠 헤르만스 자가-지속 서열 복제 시스템
US5112734A (en) * 1989-05-26 1992-05-12 Gene-Trak Systems Target-dependent synthesis of an artificial gene for the synthesis of a replicatable rna
DE69034177T2 (de) * 1989-07-11 2005-10-27 Gen-Probe Inc., San Diego Verfahren zur Amplifikation von Nukleinsäuresequenzen
CA2040503A1 (en) * 1990-04-25 1991-10-26 James E. Stefano Selective amplification system using q beta replicase

Also Published As

Publication number Publication date
AU9165091A (en) 1992-08-17
ATE159763T1 (de) 1997-11-15
DE69128077D1 (de) 1997-12-04
WO1992012261A1 (en) 1992-07-23
US20020192677A1 (en) 2002-12-19
US6677140B2 (en) 2004-01-13
EP0519053B1 (en) 1997-10-29
DE69128077T2 (de) 1998-02-26
JPH05505111A (ja) 1993-08-05
CA2076750A1 (en) 1992-07-01
AU2022295A (en) 1995-09-21
EP0519053A1 (en) 1992-12-23
KR100231383B1 (ko) 1999-11-15
US6090589A (en) 2000-07-18
ES2108748T3 (es) 1998-01-01
JP3183510B2 (ja) 2001-07-09
CA2076750C (en) 2003-07-08
AU694199B2 (en) 1998-07-16
EP0519053A4 (en) 1993-03-31
US6369207B1 (en) 2002-04-09

Similar Documents

Publication Publication Date Title
DK0519053T3 (da) Nucleinsyreamplifikation med DNA-afhængig RNA-polymeraseaktivitet hos RNA-replicaser
ATE394410T1 (de) Hochspezifische primer, amplifizierungsverfahren und kits
DK0408295T3 (da) Fremgangsmåder til opformering af nukleinsyresekvenser
ATE154029T1 (de) 7-deazapurin modifizierte oligonukleotide
DK496185D0 (da) Autonome replikationssekvenser for gaerstammer af slaegten pichia
DK337587A (da) Alkynylamino-nucleotider og deres fremstilling samt ved fremstillingen anvendelige 7-iodnucleotider
DK0698105T3 (da) Nukleotidsekvenser til styring af ekspressionen af DNAsekvenser i en værtscelle
DE69329636D1 (de) Verfahren zur Vervielfältigung von Nukleinsäuresequenzen
ATE420192T1 (de) Verfahren zur verringerung der antigenität des adeno-assoziierten virus strukturproteins
EP0774518A3 (en) Nucleic acid probes complementary to Human Papillomavirus nucleic acid and related methods and kits
CA2084790A1 (en) Endonucleases
EP0745675A3 (en) A method of amplifying nucleic acid and a reagent therefor
DK0404625T3 (da) Oligonukleotidsekvenser til amplifikation af genomer af retrovirus af HIV-2 og SIV-typen samt deres anvendelser til in vitro-diagnose af infektioner forårsaget af disse virus
DE69427876D1 (de) Methode zur detektion einer gezielten nukleinsäure
AU6144294A (en) Plant virus resistance conferring polyribozyme and resistant plants producing same
HUP0202852A2 (hu) Módosított ubiquitin-szabályozó rendszer
GB9615498D0 (en) Kinase
EP1411117A4 (en) OLIGONUCLEOTIDES FOR THE DETECTION OF THE TUBERCELAIN CROP AND PROPOSED PROCESS
EP1559794A3 (en) Multiplex PCR primer set for human HNF-1alpha gene amplification
DK0463043T3 (da) Fremgangsmåde til stabilisering af hybridiseringen af komplementære polynukleotidsekvenser