DK0506792T3 - Insulinpræparat, der indeholder nikotinsyre eller nikotinamid - Google Patents

Insulinpræparat, der indeholder nikotinsyre eller nikotinamid

Info

Publication number
DK0506792T3
DK0506792T3 DK91901711.1T DK91901711T DK0506792T3 DK 0506792 T3 DK0506792 T3 DK 0506792T3 DK 91901711 T DK91901711 T DK 91901711T DK 0506792 T3 DK0506792 T3 DK 0506792T3
Authority
DK
Denmark
Prior art keywords
nicotinic acid
nicotinamide
pct
preparation containing
insulin preparation
Prior art date
Application number
DK91901711.1T
Other languages
Danish (da)
English (en)
Inventor
Klavs Holger Jorgensen
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DK654389A external-priority patent/DK654389D0/da
Priority claimed from DK7190A external-priority patent/DK7190D0/da
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Application granted granted Critical
Publication of DK0506792T3 publication Critical patent/DK0506792T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/28Insulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Endocrinology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Obesity (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
DK91901711.1T 1989-12-21 1990-12-20 Insulinpræparat, der indeholder nikotinsyre eller nikotinamid DK0506792T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK654389A DK654389D0 (da) 1989-12-21 1989-12-21 Laegemiddel
DK7190A DK7190D0 (da) 1990-01-10 1990-01-10 Laegemiddel

Publications (1)

Publication Number Publication Date
DK0506792T3 true DK0506792T3 (da) 1995-10-09

Family

ID=26063239

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91901711.1T DK0506792T3 (da) 1989-12-21 1990-12-20 Insulinpræparat, der indeholder nikotinsyre eller nikotinamid

Country Status (10)

Country Link
US (1) US5382574A (de)
EP (1) EP0506792B1 (de)
JP (1) JP3122128B2 (de)
AT (1) ATE122567T1 (de)
AU (1) AU641721B2 (de)
CA (1) CA2070814A1 (de)
DE (1) DE69019534T2 (de)
DK (1) DK0506792T3 (de)
ES (1) ES2072596T3 (de)
WO (1) WO1991009617A1 (de)

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3562195A (en) * 1994-10-04 1996-04-26 Novo Nordisk A/S Preparations containing aspb28 human insulin and nicotinamide
US5830999A (en) * 1995-01-26 1998-11-03 Regents Of The University Of California Stabilization of insulin through ligand binding interations
EP0880969A1 (de) 1997-05-28 1998-12-02 Applied Research Systems ARS Holdings N.V. Im physiologischem Medium schwerlösliche pharmazeutische Peptidezusammensetzungen
CA2343268A1 (en) 1998-09-17 2000-03-23 Eli Lilly And Company Protein formulations
US6573237B2 (en) 2001-03-16 2003-06-03 Eli Lilly And Company Protein formulations
EP2264065B1 (de) * 2003-08-05 2017-03-08 Novo Nordisk A/S Neue insulinderivate
US9737511B2 (en) * 2004-05-24 2017-08-22 Geoffrey C. GURTNER Method of treating or preventing pathologic effects of acute increases in hyperglycemia and/or acute increases of free fatty acid flux
JP2008500347A (ja) * 2004-05-24 2008-01-10 ニュー・ヨーク・ユニヴァーシティー 高血糖症による血糖の急激な増加及び/又は急激な遊離脂肪酸流動の増加の病理学的影響の治療方法又は予防方法
PT1969004E (pt) 2005-12-28 2011-11-25 Novo Nordisk As Composições que compreendem uma insulina acilada e zinco e método para criar tais composições
ES2744384T3 (es) 2007-06-13 2020-02-24 Novo Nordisk As Formulación farmacéutica que comprende un derivado de insulina
US10098857B2 (en) 2008-10-10 2018-10-16 The Board Of Trustees Of The Leland Stanford Junior University Topical and transdermal delivery of HIF-1 modulators to prevent and treat chronic wounds
US9603904B2 (en) 2008-10-30 2017-03-28 Novo Nordisk A/S Treating diabetes melitus using insulin injections with less than daily injection frequency
US9018190B2 (en) 2009-03-27 2015-04-28 Adocia Functionalized oligosaccharides
FR2943538B1 (fr) 2009-03-27 2011-05-20 Adocia Formulation a action rapide d'insuline recombinante humaine
PL2340033T3 (pl) * 2009-06-26 2014-03-31 Novo Nordisk As Preparat zawierający insulinę, nikotynamid i argininę
AU2013203134B2 (en) * 2009-06-26 2016-05-12 Novo Nordisk A/S Preparation comprising insulin, nicotinamide and an amino acid
BR112013010345A2 (pt) 2010-10-27 2017-07-25 Novo Nordisk As tratamento de diabetes melitus usando as injeções de insulina administradas com intervalos de variação da injeção
US20130331320A1 (en) 2010-12-14 2013-12-12 Novo Nordisk A/S Fast-acting insulin in combination with long-acting insulin
KR20140030125A (ko) 2010-12-14 2014-03-11 노보 노르디스크 에이/에스 인슐린, 니코틴아미드 및 아미노산을 포함하는 제제
US20130231281A1 (en) 2011-11-02 2013-09-05 Adocia Rapid acting insulin formulation comprising an oligosaccharide
WO2013130935A1 (en) * 2012-03-02 2013-09-06 Genentech, Inc. Amido-benzyl sulfoxide derivatives
WO2013130943A1 (en) * 2012-03-02 2013-09-06 Genentech, Inc. Alkyl-and di-substituted amido-benzyl sulfonamide derivatives
EP2873422A4 (de) 2012-07-10 2015-12-30 Takeda Pharmaceutical Pharmazeutische zubereitung zur injektion
PL2919804T3 (pl) 2012-11-13 2018-07-31 Adocia Szybko działająca formulacja insuliny zawierająca podstawiony związek anionowy
EP2991672A1 (de) 2013-04-30 2016-03-09 Novo Nordisk A/S Neuartiges verabreichungsschema
WO2015120457A1 (en) * 2014-02-10 2015-08-13 Biodel Inc. Stabilized ultra-rapid-acting insulin formulations
AR099569A1 (es) * 2014-02-28 2016-08-03 Novo Nordisk As Derivados de insulina y los usos médicos de estos
EP3113791B1 (de) * 2014-03-07 2018-12-26 Jørgensen, Klavs Holger Neuartige, schnell wirkende insulinpräparate
FR3020947B1 (fr) 2014-05-14 2018-08-31 Adocia Composition aqueuse comprenant au moins une proteine et un agent solubilisant, sa preparation et ses utilisations
US9795678B2 (en) 2014-05-14 2017-10-24 Adocia Fast-acting insulin composition comprising a substituted anionic compound and a polyanionic compound
JP2018531900A (ja) * 2015-08-25 2018-11-01 ノヴォ ノルディスク アー/エス 新規インスリン誘導体及びその医学的使用
EP3341401A1 (de) * 2015-08-25 2018-07-04 Novo Nordisk A/S Neuartige insulinderivate und medizinische verwendungen davon
FR3043557B1 (fr) 2015-11-16 2019-05-31 Adocia Composition a action rapide d'insuline comprenant un citrate substitue
GB201607918D0 (en) 2016-05-06 2016-06-22 Arecor Ltd Novel formulations
CA3034971A1 (en) 2016-09-29 2018-04-05 Arecor Limited A pharmaceutical insulin formulation
WO2018138376A1 (en) 2017-01-30 2018-08-02 Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) Novel igfr-like 2 receptor and uses thereof
GB201707187D0 (en) * 2017-05-05 2017-06-21 Arecor Ltd Novel formulations
GB201707188D0 (en) 2017-05-05 2017-06-21 Arecor Ltd Novel formulations
GB201707189D0 (en) 2017-05-05 2017-06-21 Arecor Ltd Novel formulations
US11331288B2 (en) 2017-09-14 2022-05-17 The Board Of Trustees Of The Leland Stanford Junior University Conditioning irradiated tissue for increasing vascularity
IL277720B2 (en) 2018-04-04 2024-03-01 Arecor Ltd A medical infusion pump system for administration of an insulin compound
CA3094237A1 (en) 2018-04-04 2019-10-10 Arecor Limited Medical infusion pump system for the delivery of an insulin compound
US20210093775A1 (en) 2018-04-04 2021-04-01 Arecor Limited Medical infusion pump system for the delivery of an insulin compound
TWI829687B (zh) 2018-05-07 2024-01-21 丹麥商諾佛 儂迪克股份有限公司 包含glp-1促效劑與n-(8-(2-羥基苯甲醯基)胺基)辛酸之鹽的固體組成物
WO2019243627A1 (fr) 2018-06-23 2019-12-26 Adocia Dispositif pour injecter une solution d'insuline(s)
FR3083985A1 (fr) 2018-07-23 2020-01-24 Adocia Dispositif pour injecter une solution d'insuline(s)
FR3083984A1 (fr) 2018-07-23 2020-01-24 Adocia Dispositif pour injecter une solution d'insuline(s)
US10335464B1 (en) 2018-06-26 2019-07-02 Novo Nordisk A/S Device for titrating basal insulin
BR112022009510A2 (pt) 2019-12-11 2022-08-16 Novo Nordisk As Análogo de insulina, composição farmacêutica, e, método de tratamento, prevenção ou alívio de uma doença ou distúrbio ou condição
GB202004814D0 (en) 2020-04-01 2020-05-13 Arecor Ltd Novel formulations

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2179384A (en) * 1937-04-05 1939-11-07 Univ Alberta Therapeutic composition and process of making it
US2538018A (en) * 1944-04-04 1951-01-16 Nordisk Insulinlab Crystalline product of insulin and alkaline protein and process of making it
US2793977A (en) * 1951-08-31 1957-05-28 Caspe Saul Compositions and method for reducing blood sugar concentration
DK116527B (da) * 1967-03-01 1970-01-19 Nordisk Insulinlab Fremgangsmåde til fremstilling af en hurtigtvirkende, holdbar, neutral opløsning af rent krystallinsk okseinsulin eller okseinsulin, der ved tilsætning af Zn er krystalliserbart i vand, eller blandinger af okseinsulin og insulin af anden oprindelse.
GB1603639A (en) * 1978-05-26 1981-11-25 Haggar H Composition for application to the hair and scalp
US5155096A (en) * 1987-06-15 1992-10-13 Garcia Y Bellon Donato P Method for potentiation of a therapeutic agent
CA1299102C (en) * 1987-06-15 1992-04-21 Steven G. Ayre Insulin potentiation therapy
ATE108064T1 (de) * 1987-10-08 1994-07-15 Andor Bilas Stoffgemisch zur stabilisierung der stoffwechsel- lage.

Also Published As

Publication number Publication date
DE69019534D1 (de) 1995-06-22
EP0506792A1 (de) 1992-10-07
EP0506792B1 (de) 1995-05-17
AU7047191A (en) 1991-07-24
AU641721B2 (en) 1993-09-30
WO1991009617A1 (en) 1991-07-11
JP3122128B2 (ja) 2001-01-09
CA2070814A1 (en) 1991-06-22
DE69019534T2 (de) 1995-09-21
US5382574A (en) 1995-01-17
JPH05502234A (ja) 1993-04-22
ATE122567T1 (de) 1995-06-15
ES2072596T3 (es) 1995-07-16

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