DK0490667T3 - HIV-proteaseinhibitorer - Google Patents

HIV-proteaseinhibitorer

Info

Publication number
DK0490667T3
DK0490667T3 DK91311549T DK91311549T DK0490667T3 DK 0490667 T3 DK0490667 T3 DK 0490667T3 DK 91311549 T DK91311549 T DK 91311549T DK 91311549 T DK91311549 T DK 91311549T DK 0490667 T3 DK0490667 T3 DK 0490667T3
Authority
DK
Denmark
Prior art keywords
protease inhibitors
hiv protease
inhibitors
aids
hiv
Prior art date
Application number
DK91311549T
Other languages
English (en)
Inventor
Tsutomu Mimoto
Naoko Hattori
Yuuichi Nagano
Makoto Shintani
Yoshiaki Kiso
Original Assignee
Japan Energy Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Japan Energy Corp filed Critical Japan Energy Corp
Application granted granted Critical
Publication of DK0490667T3 publication Critical patent/DK0490667T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02—Linear peptides containing at least one abnormal peptide link
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0202—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-X-X-C(=0)-, X being an optionally substituted carbon atom or a heteroatom, e.g. beta-amino acids
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
DK91311549T 1990-12-11 1991-12-11 HIV-proteaseinhibitorer DK0490667T3 (da)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP40967390 1990-12-11
JP2575591 1991-01-25
JP8997691 1991-03-28
JP16917491 1991-06-14
JP30404391 1991-10-23

Publications (1)

Publication Number Publication Date
DK0490667T3 true DK0490667T3 (da) 1999-12-13

Family

ID=27520768

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91311549T DK0490667T3 (da) 1990-12-11 1991-12-11 HIV-proteaseinhibitorer

Country Status (10)

Country Link
EP (1) EP0490667B1 (da)
JP (1) JP2700511B2 (da)
AT (1) ATE181080T1 (da)
AU (1) AU653972B2 (da)
CA (1) CA2056911C (da)
DE (1) DE69131317T2 (da)
DK (1) DK0490667T3 (da)
ES (1) ES2134764T3 (da)
FI (1) FI108113B (da)
GR (1) GR3031004T3 (da)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5976541A (en) * 1988-01-26 1999-11-02 The United States Of America As Represented By The Department Of Health And Human Services Potent peptide for stimulation of cytotoxic T lymphocytes specific for the HIV-1 envelope
JP2500034B2 (ja) * 1991-02-08 1996-05-29 三共株式会社 β−アミノ−α−ヒドロキシカルボン酸誘導体
WO1993018006A1 (en) * 1992-03-11 1993-09-16 Narhex Limited Amine derivatives of oxo- and hydroxy-substitued hydrocarbons
US5888992A (en) * 1992-03-11 1999-03-30 Narhex Limited Polar substituted hydrocarbons
DE69333270T2 (de) 1992-03-11 2004-08-05 Narhex Ltd. Aminderivate von oxo- und hydroxy- substituierten kohlenwasserstoffen
US6071895A (en) * 1992-03-11 2000-06-06 Narhex Limited Polar-substituted hydrocarbons
US5644028A (en) * 1992-05-13 1997-07-01 Japan Energy Corporation Process for producing peptide derivatives and salts therefor
US5559256A (en) * 1992-07-20 1996-09-24 E. R. Squibb & Sons, Inc. Aminediol protease inhibitors
NZ248332A (en) * 1992-08-07 1995-01-27 Sankyo Co Hiv protease inhibitor and its use
US5484926A (en) * 1993-10-07 1996-01-16 Agouron Pharmaceuticals, Inc. HIV protease inhibitors
US5846993A (en) * 1992-12-22 1998-12-08 Agouron Pharmaceuticals, Inc. HIV protease inhibitors
IL110898A0 (en) * 1993-09-10 1994-11-28 Narhex Australia Pty Ltd Polar-substituted hydrocarbons
IL110752A (en) * 1993-09-13 2000-07-26 Abbott Lab Liquid semi-solid or solid pharmaceutical composition for an HIV protease inhibitor
US5559158A (en) * 1993-10-01 1996-09-24 Abbott Laboratories Pharmaceutical composition
US5527829A (en) * 1994-05-23 1996-06-18 Agouron Pharmaceuticals, Inc. HIV protease inhibitors
EP0706794B1 (en) * 1994-10-14 2001-12-12 Japan Energy Corporation Anti-aids pharmaceutical preparations and processes for the production thereof
AU4188096A (en) * 1994-12-14 1996-07-03 Sankyo Company Limited Ahpba-containing tripeptide derivative
US6008228A (en) * 1995-06-06 1999-12-28 Hoffman-La Roche Inc. Pharmaceutical compositions containing proteinase inhibitors
US5932550A (en) * 1995-06-30 1999-08-03 Japan Energy Corporation Dipeptide compound or pharmaceutically acceptable salt thereof and medical use thereof
US6222043B1 (en) 1995-06-30 2001-04-24 Japan Energy Corporation Methods of preparing novel dipeptide compounds or pharmaceutically acceptable salts thereof
US5914332A (en) 1995-12-13 1999-06-22 Abbott Laboratories Retroviral protease inhibiting compounds
US5705647A (en) * 1996-09-05 1998-01-06 Agouron Pharmaceuticals, Inc. Intermediates for making HIV-protease inhibitors
US5962725A (en) 1996-09-05 1999-10-05 Agouron Pharmaceuticals, Inc. Intermediate compounds useful for making HIV protease inhibitors such as nelfinavir
US5925759A (en) 1996-09-05 1999-07-20 Agouron Pharmaceuticals, Inc. Methods of making HIV-protease inhibitors and intermediates for making HIV-protease inhibitors
US6174905B1 (en) * 1996-09-30 2001-01-16 Mitsui Chemicals, Inc. Cell differentiation inducer
US6794392B1 (en) 1996-09-30 2004-09-21 Schering Aktiengesellschaft Cell differentiation inducer
US6232333B1 (en) 1996-11-21 2001-05-15 Abbott Laboratories Pharmaceutical composition
US6291432B1 (en) 1996-12-27 2001-09-18 Japan Energy Corporation Tripeptide compounds and anti-AIDS medicine
US6001851A (en) * 1997-03-13 1999-12-14 Agouron Pharmaceuticals, Inc. HIV protease inhibitors
US6084107A (en) * 1997-09-05 2000-07-04 Agouron Pharmaceuticals, Inc. Intermediates for making HIV-protease inhibitors
BR0011864A (pt) 2000-01-19 2004-07-20 Abbott Lab Formulações farmacêuticas
SE0000382D0 (sv) 2000-02-07 2000-02-07 Astrazeneca Ab New process
HN2002000136A (es) 2001-06-11 2003-07-31 Basf Ag Inhibidores de la proteasa del virus hiv, compuestos que contienen a los mismos, sus usos farmaceuticos y los materiales para su sintesis
US7094909B2 (en) 2001-06-11 2006-08-22 Agouron Pharmaceuticals, Inc. HIV protease inhibitors, compositions containing the same, their pharmaceutical uses and materials for their synthesis
US7169932B2 (en) 2001-06-11 2007-01-30 Pfizer Inc. HIV protease inhibitors, compositions containing the same, their pharmaceutical uses, material for their synthesis
EP1463807A4 (en) 2001-12-19 2006-04-12 Bristol Myers Squibb Co FORMATHYDROGENASE FROM PICHIA PASTORIS AND USES THEREOF
EP1604656A1 (en) 2004-06-09 2005-12-14 Schwarz Pharma Ag Novel use of peptide compounds for treating amyotrophic lateral sclerosis (ALS)
JP5260062B2 (ja) 2006-01-20 2013-08-14 株式会社カネカ β−アミノ−α−ヒドロキシ酸アミド誘導体の製造法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4656269A (en) * 1986-04-15 1987-04-07 Kissei Pharmaceutical Co., Ltd. Histidine derivatives
DE3751570T2 (de) * 1986-06-05 1996-04-18 Zeneca Inc Difluoro-Peptid-Verbindungen.
JPS6322081A (ja) * 1986-07-11 1988-01-29 Kissei Pharmaceut Co Ltd 新規なアミノ酸誘導体

Also Published As

Publication number Publication date
ATE181080T1 (de) 1999-06-15
JPH05170722A (ja) 1993-07-09
CA2056911C (en) 1998-09-22
DE69131317D1 (de) 1999-07-15
GR3031004T3 (en) 1999-12-31
FI915819A (fi) 1992-06-12
AU653972B2 (en) 1994-10-20
JP2700511B2 (ja) 1998-01-21
EP0490667A3 (en) 1993-05-05
FI915819A0 (fi) 1991-12-11
EP0490667B1 (en) 1999-06-09
AU8890091A (en) 1992-06-18
CA2056911A1 (en) 1992-06-12
ES2134764T3 (es) 1999-10-16
FI108113B (fi) 2001-11-30
DE69131317T2 (de) 2000-01-13
EP0490667A2 (en) 1992-06-17

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