DK0463115T3 - - Google Patents
Info
- Publication number
- DK0463115T3 DK0463115T3 DK90906035.2T DK90906035T DK0463115T3 DK 0463115 T3 DK0463115 T3 DK 0463115T3 DK 90906035 T DK90906035 T DK 90906035T DK 0463115 T3 DK0463115 T3 DK 0463115T3
- Authority
- DK
- Denmark
- Prior art keywords
- somatotropin
- glutamine
- arginine
- residues
- lysine residue
- Prior art date
Links
- 102000018997 Growth Hormone Human genes 0.000 abstract 2
- 108010051696 Growth Hormone Proteins 0.000 abstract 2
- 239000004475 Arginine Substances 0.000 abstract 1
- ODKSFYDXXFIFQN-BYPYZUCNSA-P L-argininium(2+) Chemical compound NC(=[NH2+])NCCC[C@H]([NH3+])C(O)=O ODKSFYDXXFIFQN-BYPYZUCNSA-P 0.000 abstract 1
- ZDXPYRJPNDTMRX-VKHMYHEASA-N L-glutamine Chemical compound OC(=O)[C@@H](N)CCC(N)=O ZDXPYRJPNDTMRX-VKHMYHEASA-N 0.000 abstract 1
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 abstract 1
- ZDXPYRJPNDTMRX-UHFFFAOYSA-N glutamine Natural products OC(=O)C(N)CCC(N)=O ZDXPYRJPNDTMRX-UHFFFAOYSA-N 0.000 abstract 1
- 125000003588 lysine group Chemical group [H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])(N([H])[H])C(*)=O 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/61—Growth hormone [GH], i.e. somatotropin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
- C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Endocrinology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32390189A | 1989-03-15 | 1989-03-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0463115T3 true DK0463115T3 (hu) | 1997-02-17 |
Family
ID=23261207
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK90906035.2T DK0463115T3 (hu) | 1989-03-15 | 1990-01-23 |
Country Status (11)
| Country | Link |
|---|---|
| EP (2) | EP0463115B1 (hu) |
| JP (1) | JPH04504060A (hu) |
| KR (1) | KR920700292A (hu) |
| AT (1) | ATE142270T1 (hu) |
| AU (1) | AU629929B2 (hu) |
| CA (1) | CA2045173A1 (hu) |
| DE (1) | DE69028396T2 (hu) |
| DK (1) | DK0463115T3 (hu) |
| ES (1) | ES2091241T3 (hu) |
| HU (1) | HUT58796A (hu) |
| WO (1) | WO1990010706A1 (hu) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6140071A (en) * | 1994-01-27 | 2000-10-31 | Somatogen, Inc. | Proteins with mutations to decrease N-terminal methylation |
| US7547529B1 (en) | 2000-05-10 | 2009-06-16 | Asubio Pharma Co., Ltd. | Methods for reducing the formation of by-products in the production of recombinant polypeptides |
-
1990
- 1990-01-23 ES ES90906035T patent/ES2091241T3/es not_active Expired - Lifetime
- 1990-01-23 CA CA002045173A patent/CA2045173A1/en not_active Abandoned
- 1990-01-23 KR KR1019900702445A patent/KR920700292A/ko not_active Application Discontinuation
- 1990-01-23 AT AT90906035T patent/ATE142270T1/de not_active IP Right Cessation
- 1990-01-23 AU AU54060/90A patent/AU629929B2/en not_active Ceased
- 1990-01-23 DK DK90906035.2T patent/DK0463115T3/da active
- 1990-01-23 EP EP90906035A patent/EP0463115B1/en not_active Expired - Lifetime
- 1990-01-23 DE DE69028396T patent/DE69028396T2/de not_active Expired - Fee Related
- 1990-01-23 JP JP2505682A patent/JPH04504060A/ja active Pending
- 1990-01-23 EP EP96101997A patent/EP0719792A2/en not_active Withdrawn
- 1990-01-23 HU HU903721A patent/HUT58796A/hu unknown
- 1990-01-23 WO PCT/US1990/000326 patent/WO1990010706A1/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| AU629929B2 (en) | 1992-10-15 |
| JPH04504060A (ja) | 1992-07-23 |
| ATE142270T1 (de) | 1996-09-15 |
| EP0719792A2 (en) | 1996-07-03 |
| WO1990010706A1 (en) | 1990-09-20 |
| HUT58796A (en) | 1992-03-30 |
| DE69028396D1 (de) | 1996-10-10 |
| CA2045173A1 (en) | 1990-09-16 |
| EP0719792A3 (hu) | 1996-07-24 |
| HU903721D0 (en) | 1991-12-30 |
| EP0463115B1 (en) | 1996-09-04 |
| ES2091241T3 (es) | 1996-11-01 |
| DE69028396T2 (de) | 1997-02-13 |
| KR920700292A (ko) | 1992-02-19 |
| AU5406090A (en) | 1990-10-09 |
| EP0463115A1 (en) | 1992-01-02 |
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