DK0462016T3 - Fremgangsmåde til industriel fremstilling af 4-chlor-3-sulfamoyl-N-(2,3-dihydro-2-methyl-1H-indol-1-yl)-benzamid - Google Patents

Fremgangsmåde til industriel fremstilling af 4-chlor-3-sulfamoyl-N-(2,3-dihydro-2-methyl-1H-indol-1-yl)-benzamid

Info

Publication number
DK0462016T3
DK0462016T3 DK91401582T DK91401582T DK0462016T3 DK 0462016 T3 DK0462016 T3 DK 0462016T3 DK 91401582 T DK91401582 T DK 91401582T DK 91401582 T DK91401582 T DK 91401582T DK 0462016 T3 DK0462016 T3 DK 0462016T3
Authority
DK
Denmark
Prior art keywords
dihydro
methyl
indol
benzamide
chloro
Prior art date
Application number
DK91401582T
Other languages
English (en)
Inventor
Armand Cohen
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Application granted granted Critical
Publication of DK0462016T3 publication Critical patent/DK0462016T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK91401582T 1990-06-14 1991-06-14 Fremgangsmåde til industriel fremstilling af 4-chlor-3-sulfamoyl-N-(2,3-dihydro-2-methyl-1H-indol-1-yl)-benzamid DK0462016T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9007386A FR2663324B1 (fr) 1990-06-14 1990-06-14 Nouveau procede de preparation industrielle du 4-chloro 3-sulfamoyl n-(2,3-dihydro 2-methyl 1h-indol-1-yl) benzamide.

Publications (1)

Publication Number Publication Date
DK0462016T3 true DK0462016T3 (da) 2000-03-27

Family

ID=9397579

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91401582T DK0462016T3 (da) 1990-06-14 1991-06-14 Fremgangsmåde til industriel fremstilling af 4-chlor-3-sulfamoyl-N-(2,3-dihydro-2-methyl-1H-indol-1-yl)-benzamid

Country Status (16)

Country Link
US (1) US5101040A (da)
EP (1) EP0462016B1 (da)
JP (1) JPH04279565A (da)
AT (1) ATE185137T1 (da)
AU (1) AU630815B1 (da)
CA (1) CA2044491C (da)
DE (1) DE69131657T2 (da)
DK (1) DK0462016T3 (da)
ES (1) ES2139573T3 (da)
FR (1) FR2663324B1 (da)
GR (1) GR3031339T3 (da)
IE (1) IE912004A1 (da)
NZ (1) NZ238526A (da)
OA (1) OA09365A (da)
PT (1) PT97953B (da)
ZA (1) ZA914567B (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2769016B1 (fr) * 1997-09-30 1999-10-29 Adir Procede de synthese de chloramine haute teneur
FR2864078B1 (fr) * 2003-12-17 2006-02-10 Isochem Sa Procede de synthese en continu de monoalkyl hydrazines a groupe alkyle fonctionnalise
FR2864081B1 (fr) * 2003-12-17 2006-04-28 Isochem Sa Procede de synthese de derives de cycloalkyl-hydrazines exocycliques et de derives d'heterocycloalkyl-hydrazines exocycliques.
CN100422146C (zh) * 2006-09-25 2008-10-01 天津力生制药股份有限公司 一种吲达帕胺的合成方法
US20080156740A1 (en) * 2006-12-29 2008-07-03 Amit Gupta Method for producing a stable oxidizing biocide
CN101717359B (zh) * 2009-07-15 2012-09-05 北京成宇药业有限公司 吲达帕胺的合成方法
US8532826B2 (en) * 2010-03-10 2013-09-10 Dell Product L.P. System and method for controlling temperature in an information handling system
US9020656B2 (en) 2012-03-27 2015-04-28 Dell Products L.P. Information handling system thermal control by energy conservation
CN103467355A (zh) * 2013-09-12 2013-12-25 迪沙药业集团有限公司 一种吲达帕胺的制备方法
US10136558B2 (en) 2014-07-30 2018-11-20 Dell Products L.P. Information handling system thermal management enhanced by estimated energy states
CN105418479A (zh) * 2015-11-18 2016-03-23 天津市亨必达化学合成物有限公司 一种吲达帕胺的合成方法
EP4559899A1 (en) 2023-11-21 2025-05-28 KRKA, d.d., Novo mesto Synthesis of 1-amino-2-methyl-2,3-dihydroindole by nitrosating 2-methyl-2,3-dihydro-1h-indole and then reducing the obtained 1-nitroso-2-methyl-2,3-dihydroindole with thiourea dioxide

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1095040A (en) * 1966-04-01 1967-12-13 Fmc Corp Hydrazine derivatives
GB1203691A (en) * 1968-03-06 1970-09-03 Science Union & Cie New disubstituted n-amino indoline derivatives and process for preparing them
US3676480A (en) * 1970-02-24 1972-07-11 Merck & Co Inc {60 -acylhydrazino-{62 -phenyl-propionitriles
US4570001A (en) * 1980-12-22 1986-02-11 Science Union Et Cie Process for synthesizing certain N-benzoylamino indolines
EP0054892B1 (en) * 1980-12-22 1985-09-18 SCIENCE UNION ET Cie Synthesis of indolines
JPS57206657A (en) * 1981-06-16 1982-12-18 Mitsui Toatsu Chem Inc Sulfamoylbenzoic acid derivative and remedying composition containing said derivative as active component
JPH0233030B2 (ja) * 1982-01-18 1990-07-25 Mitsui Toatsu Chemicals Surufuamoiruansokukosanjudotaioyobisoreojukoseibuntoshitefukumuchiryoyososeibutsu
JPS58124767A (ja) * 1982-01-21 1983-07-25 Mitsui Toatsu Chem Inc スルファモイル安息香酸誘導体
US4564677A (en) * 1984-01-19 1986-01-14 Usv Pharmaceutical Corp. Preparation of N-amino compounds
FR2663325B1 (fr) * 1990-06-14 1992-09-04 Adir Nouveau procede de preparation industrielle du 4-chloro 3-sulfamoyl n-(2,3-dihydro 2-methyl 1h-indol-1-yl) benzamide a partir de la 2,3-dihydro 2-methyl 1h-indole et de l'acide hydroxylamine-o-sulfonique.

Also Published As

Publication number Publication date
ATE185137T1 (de) 1999-10-15
FR2663324A1 (fr) 1991-12-20
DE69131657T2 (de) 2000-05-11
EP0462016A1 (fr) 1991-12-18
PT97953B (pt) 1998-11-30
GR3031339T3 (en) 1999-12-31
CA2044491C (fr) 1999-04-13
EP0462016B1 (fr) 1999-09-29
OA09365A (fr) 1992-09-15
NZ238526A (en) 1992-05-26
AU630815B1 (en) 1992-11-05
FR2663324B1 (fr) 1992-09-04
JPH04279565A (ja) 1992-10-05
US5101040A (en) 1992-03-31
PT97953A (pt) 1992-03-31
ZA914567B (en) 1992-03-25
IE912004A1 (en) 1991-12-18
CA2044491A1 (fr) 1991-12-15
DE69131657D1 (de) 1999-11-04
ES2139573T3 (es) 2000-02-16

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