DK0456720T3 - Granuleringer med højt ibuprofenindhold - Google Patents
Granuleringer med højt ibuprofenindholdInfo
- Publication number
- DK0456720T3 DK0456720T3 DK90902888.8T DK90902888T DK0456720T3 DK 0456720 T3 DK0456720 T3 DK 0456720T3 DK 90902888 T DK90902888 T DK 90902888T DK 0456720 T3 DK0456720 T3 DK 0456720T3
- Authority
- DK
- Denmark
- Prior art keywords
- binder
- percent
- polyvinylpyrrolidone
- granules
- ibuprofen
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- General Chemical & Material Sciences (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/306,014 US4911921A (en) | 1989-02-02 | 1989-02-02 | High ibuprofen content granulations |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0456720T3 true DK0456720T3 (da) | 1995-08-14 |
Family
ID=23183358
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK90902888.8T DK0456720T3 (da) | 1989-02-02 | 1990-01-31 | Granuleringer med højt ibuprofenindhold |
Country Status (10)
Country | Link |
---|---|
US (1) | US4911921A (da) |
EP (1) | EP0456720B1 (da) |
JP (1) | JP2556623B2 (da) |
AT (1) | ATE124257T1 (da) |
AU (1) | AU629913B2 (da) |
CA (1) | CA2045680C (da) |
DE (1) | DE69020541T2 (da) |
DK (1) | DK0456720T3 (da) |
ES (1) | ES2076358T3 (da) |
WO (1) | WO1990008542A1 (da) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5104648A (en) * | 1989-02-02 | 1992-04-14 | Mallinckrodt Specialty Chemicals Company | High ibuprofen content granulations |
US5087454A (en) * | 1990-07-30 | 1992-02-11 | American Home Products Corporation | Ibuprofen tablet |
GB9119052D0 (en) * | 1991-09-06 | 1991-10-23 | Boots Co Plc | Pharmaceutical compositions |
US5191114A (en) * | 1991-10-09 | 1993-03-02 | Sage Pharmaceuticals, Inc. | Process for enhancing the flow characteristics of ibuprofen |
US5310961A (en) * | 1993-07-02 | 1994-05-10 | Affinity Biotech, Inc. | Neomorphic ibuprofen |
US6348216B1 (en) * | 1996-06-10 | 2002-02-19 | Knoll Pharmaceutical Company | Ibuprofen and narcotic analgesic compositions |
US6361794B1 (en) | 1996-06-12 | 2002-03-26 | Basf Corporation | Method of making ibuprofen and narcotic analgesic composition |
US5837292A (en) * | 1996-07-03 | 1998-11-17 | Yamanouchi Europe B.V. | Granulate for the preparation of fast-disintegrating and fast-dissolving compositions containing a high amount of drug |
FR2772617B1 (fr) * | 1997-12-19 | 2001-03-09 | Besins Iscovesco Lab | Comprime de progesterone et son procede de preparation |
IT1301966B1 (it) | 1998-07-30 | 2000-07-20 | Zambon Spa | Composizioni farmaceutiche ad attivita' analgesica |
US6251945B1 (en) | 1999-01-14 | 2001-06-26 | Knoll Aktiengesellschaft | Pharmaceutical mixture comprising a combination of a profen and other active compounds |
DE10003757A1 (de) * | 2000-01-28 | 2001-08-02 | Knoll Ag | Ibuprofen-Wirkstoffzubereitung |
GB0209265D0 (en) | 2002-04-23 | 2002-06-05 | Novartis Ag | Organic compounds |
CZ296100B6 (cs) † | 2002-04-29 | 2006-01-11 | EGIS Gyógyszergyár Rt. | Zpusob prípravy tablet z farmaceuticky aktivních látek majících nevýhodné tabletacní vlastnosti s granulacní kapalinou obsahující mikrokrystalickou celulózu |
US20040253308A1 (en) * | 2003-04-29 | 2004-12-16 | Barr Laboratories, Inc. | Surface-treated modafinil particles |
BRPI0512900A (pt) * | 2004-06-30 | 2008-04-15 | Albemarle Corp | composição farmacêutica compreendendo de ibuprofeno, processo de preparação dos gránulos enriquecidos em ibuprofeno e os gránulos secos feitos por este processo |
EP1737847B1 (en) | 2004-07-30 | 2008-06-04 | Torrent Pharmaceuticals Ltd | Nebivolol and its pharmaceutically acceptable salts, process for preparation and pharmaceutical compositions of nebivolol |
DK1884242T3 (da) | 2005-05-26 | 2013-05-06 | Dainippon Sumitomo Pharma Co | Farmaceutisk sammensætning omfattende lurasidon |
CA2577760A1 (en) * | 2006-02-27 | 2007-08-27 | Tyco Healthcare Group Lp | Pressurized dip coating system |
US20070212417A1 (en) * | 2006-03-07 | 2007-09-13 | Cherukuri S R | Compressible resilient granules and formulations prepared therefrom |
US20080069889A1 (en) * | 2006-03-07 | 2008-03-20 | Cherukuri S R | Compressible resilient granules and formulations prepared therefrom |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3108046A (en) * | 1960-11-25 | 1963-10-22 | Smith Kline French Lab | Method of preparing high dosage sustained release tablet and product of this method |
US4209513A (en) * | 1974-02-14 | 1980-06-24 | Burroughs Wellcome Co. | Tablet formulation |
US4661521A (en) * | 1984-04-30 | 1987-04-28 | Mallinckrodt, Inc. | Direct tableting acetaminophen compositions |
US4609675A (en) * | 1984-08-17 | 1986-09-02 | The Upjohn Company | Stable, high dose, high bulk density ibuprofen granulations for tablet and capsule manufacturing |
US4753801A (en) * | 1985-10-25 | 1988-06-28 | Eli Lilly And Company | Sustained release tablets |
US4757090A (en) * | 1986-07-14 | 1988-07-12 | Mallinckrodt, Inc. | Direct tableting acetaminophen compositions |
US4806359A (en) * | 1987-04-22 | 1989-02-21 | Mcneilab, Inc. | Iburprofen sustained release matrix and process |
US4837031A (en) * | 1987-09-17 | 1989-06-06 | Mallinckrodt, Inc. | Compositions containing ibuprofen |
-
1989
- 1989-02-02 US US07/306,014 patent/US4911921A/en not_active Expired - Lifetime
-
1990
- 1990-01-31 WO PCT/US1990/000564 patent/WO1990008542A1/en active IP Right Grant
- 1990-01-31 AU AU50369/90A patent/AU629913B2/en not_active Expired
- 1990-01-31 JP JP2503127A patent/JP2556623B2/ja not_active Expired - Lifetime
- 1990-01-31 DK DK90902888.8T patent/DK0456720T3/da active
- 1990-01-31 CA CA002045680A patent/CA2045680C/en not_active Expired - Lifetime
- 1990-01-31 ES ES90902888T patent/ES2076358T3/es not_active Expired - Lifetime
- 1990-01-31 EP EP90902888A patent/EP0456720B1/en not_active Expired - Lifetime
- 1990-01-31 DE DE69020541T patent/DE69020541T2/de not_active Expired - Lifetime
- 1990-01-31 AT AT90902888T patent/ATE124257T1/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
JP2556623B2 (ja) | 1996-11-20 |
JPH04503069A (ja) | 1992-06-04 |
DE69020541D1 (de) | 1995-08-03 |
ATE124257T1 (de) | 1995-07-15 |
EP0456720A1 (en) | 1991-11-21 |
AU629913B2 (en) | 1992-10-15 |
US4911921A (en) | 1990-03-27 |
WO1990008542A1 (en) | 1990-08-09 |
AU5036990A (en) | 1990-08-24 |
CA2045680C (en) | 1997-01-14 |
ES2076358T3 (es) | 1995-11-01 |
DE69020541T2 (de) | 1995-11-02 |
EP0456720B1 (en) | 1995-06-28 |
CA2045680A1 (en) | 1990-08-03 |
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