DK0409052T3 - Middel, der indeholder et antikoagulans - Google Patents

Middel, der indeholder et antikoagulans

Info

Publication number
DK0409052T3
DK0409052T3 DK90113186.2T DK90113186T DK0409052T3 DK 0409052 T3 DK0409052 T3 DK 0409052T3 DK 90113186 T DK90113186 T DK 90113186T DK 0409052 T3 DK0409052 T3 DK 0409052T3
Authority
DK
Denmark
Prior art keywords
anticoagulant
agent containing
agent
analogues
besides
Prior art date
Application number
DK90113186.2T
Other languages
Danish (da)
English (en)
Inventor
Christiaan Dr Reutelingsperger
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Application granted granted Critical
Publication of DK0409052T3 publication Critical patent/DK0409052T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0491Sugars, nucleosides, nucleotides, oligonucleotides, nucleic acids, e.g. DNA, RNA, nucleic acid aptamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Zoology (AREA)
  • Inorganic Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Solid Fuels And Fuel-Associated Substances (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK90113186.2T 1989-07-15 1990-07-11 Middel, der indeholder et antikoagulans DK0409052T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3923500 1989-07-15

Publications (1)

Publication Number Publication Date
DK0409052T3 true DK0409052T3 (da) 1993-06-07

Family

ID=6385154

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90113186.2T DK0409052T3 (da) 1989-07-15 1990-07-11 Middel, der indeholder et antikoagulans

Country Status (9)

Country Link
US (1) US5296467A (fr)
EP (1) EP0409052B1 (fr)
JP (1) JPH03135920A (fr)
AT (1) ATE89169T1 (fr)
CA (1) CA2021146A1 (fr)
DD (1) DD296613A5 (fr)
DE (2) DE4022010A1 (fr)
DK (1) DK0409052T3 (fr)
ES (1) ES2055234T3 (fr)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5571667A (en) * 1987-10-01 1996-11-05 Chu; Albert E. Elongated membrane flow-through diagnostic device and method
CA2116227A1 (fr) * 1991-09-23 1993-04-01 Christine A. Towle Annexine xi
DE4341274A1 (de) * 1993-12-03 1995-06-14 Boehringer Ingelheim Int Beschichtung von medizinischen Materialien mit Annexinen
US20030220233A1 (en) 1994-01-24 2003-11-27 Neorx Corporation Radiolabeled annexins
US5968477A (en) * 1994-01-24 1999-10-19 Neorx Corporation Radiolabeled annexin conjugates with hexose and a chelator
US6180596B1 (en) * 1995-05-18 2001-01-30 Wisconsin Alumni Research Foundation Methods of inhibiting phospholipase A2 and phospholipase A2 stimulator activities
IL140700A0 (en) 1998-07-13 2002-02-10 Univ Texas Cancer treatment methods using therapeutic conjugates that bind to aminophospholipids
US6406693B1 (en) 1998-07-13 2002-06-18 Board Of Regents, The University Of Texas System Cancer treatment methods using antibodies to aminophospholipids
US6818213B1 (en) 1998-07-13 2004-11-16 Board Of Regents, The University Of Texas System Cancer treatment compositions comprising therapeutic conjugates that bind to aminophospholipids
NZ508950A (en) 1998-07-13 2003-10-31 Univ Texas Cancer treatment methods using antibodies to aminophospholipids
WO2001059455A2 (fr) * 2000-02-08 2001-08-16 Acspurt B.V. Materiau et procede pour l'immobilisation d'especes bioactives
US7645739B2 (en) * 2001-02-21 2010-01-12 Alavita Pharmaceuticals, Inc. Modified annexin compositions and methods of using same
US7635680B2 (en) * 2001-02-21 2009-12-22 Alavita Pharmaceuticals, Inc. Attenuation of reperfusion injury
US7635676B2 (en) 2001-02-21 2009-12-22 Alavita Pharmaccuticals, Inc. Modified annexin proteins and methods for their use in organ transplantation
US20090291086A1 (en) * 2001-02-21 2009-11-26 Alavita Pharmaceuticals, Inc. Compositions and Methods for Treating Cerebral Thrombosis and Global Cerebral Ischemia
JP2004528025A (ja) * 2001-02-21 2004-09-16 サーロメッド・インコーポレーテッド 修飾されたアネキシン蛋白質及び血栓症を防ぐための方法
US6982154B2 (en) * 2002-02-21 2006-01-03 Surromed, Inc. Modified annexin proteins and methods for treating vaso-occlusive sickle-cell disease
US7893222B2 (en) * 2002-12-20 2011-02-22 University Of Houston Introduction of structural affinity handles as a tool in selective nucleic acid separations
US7393833B2 (en) * 2005-03-09 2008-07-01 The Board Of Regents Of The University Of Oklahoma Chimeric proteins with phosphatidylserine binding domains
WO2008104861A1 (fr) * 2007-02-27 2008-09-04 Karine Berthet Procédé pour le traitement d'un sujet ayant une insuffisance vasculaire dans la partie supérieure du corps, notamment une insuffisance vasculaire cérébrale ou un trouble vasculaire oculaire
EP2570458B1 (fr) 2009-02-09 2019-05-15 Mitsubishi Engineering-Plastics Corporation Composition de résine polycarbonate et produit formé à partir de celle-ci
MX2018009863A (es) 2010-08-30 2022-06-14 Evogene Ltd Polinucleotidos y polipeptidos aislados, y metodos para utilizarlos para aumentar la eficacia en el uso de nitrogeno, rendimiento, tasa de crecimiento, vigor, biomasa, contenido de aceite y/o tolerancia al estres abiotico.

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3315000A1 (de) * 1983-04-26 1984-10-31 Behringwerke Ag, 3550 Marburg Gewebeprotein pp(pfeil abwaerts)4(pfeil abwaerts), verfahren zu seiner gewinnung sowie seine verwendung
DE3418888A1 (de) * 1984-05-21 1985-11-21 Behringwerke Ag, 3550 Marburg Gewebeprotein pp(pfeil abwaerts)1(pfeil abwaerts)(pfeil abwaerts)8(pfeil abwaerts), verfahren zu seiner gewinnung sowie seine verwendung
DE3533516A1 (de) * 1984-09-21 1986-04-03 Boehringer Ingelheim KG, 6507 Ingelheim Blutgerinnungshemmende proteine, verfahren zur herstellung sowie deren verwendung
CA1265446A (fr) * 1985-09-30 1990-02-06 Masahiro Maki Substance anticoagulante, procede de preparation et anticoagulant comprenant ces substances actives
JPH0689014B2 (ja) * 1986-01-21 1994-11-09 興和株式会社 トロンビン結合性物質およびその製法
JP2593500B2 (ja) * 1986-06-24 1997-03-26 ノルデイスク ゲントフテ エー/エス ▲viii▼因子フラグメントの凝固活性複合物の製造方法
DE3710430A1 (de) * 1987-03-28 1989-01-19 Boehringer Ingelheim Int Vascular-antikoagulierende proteine, dna die diese kodieren, verfahren zu deren herstellung sowie deren verwendung
PT87083B (pt) * 1987-03-28 1992-07-31 Boehringer Ingelheim Int Processo para a preparacao de uma proteina anticoagulante vascular, de adn que codifica para esta proteina e de composicoes farmaceuticas que a contem
DE3737239A1 (de) * 1987-11-03 1989-10-12 Behringwerke Ag Gentechnische herstellung von anticoagulatorischem protein pp4
DE4021979A1 (de) * 1989-07-15 1991-01-31 Boehringer Ingelheim Int Verfahren zur reinigung von annexinen

Also Published As

Publication number Publication date
US5296467A (en) 1994-03-22
CA2021146A1 (fr) 1991-01-16
DD296613A5 (de) 1991-12-12
JPH03135920A (ja) 1991-06-10
EP0409052B1 (fr) 1993-05-12
ES2055234T3 (es) 1994-08-16
DE4022010A1 (de) 1991-01-17
EP0409052A2 (fr) 1991-01-23
DE59001418D1 (de) 1993-06-17
EP0409052A3 (en) 1991-09-18
ATE89169T1 (de) 1993-05-15

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