DK0407942T3 - Streptokinaseproteiner, hertil svarende gener, hertil svarende rekombinante plasmider, hertil svaren de transformanter samt fremgangsmåder til fremstilling heraf - Google Patents
Streptokinaseproteiner, hertil svarende gener, hertil svarende rekombinante plasmider, hertil svaren de transformanter samt fremgangsmåder til fremstilling herafInfo
- Publication number
- DK0407942T3 DK0407942T3 DK90113099.7T DK90113099T DK0407942T3 DK 0407942 T3 DK0407942 T3 DK 0407942T3 DK 90113099 T DK90113099 T DK 90113099T DK 0407942 T3 DK0407942 T3 DK 0407942T3
- Authority
- DK
- Denmark
- Prior art keywords
- streptokinase
- amino acid
- transformant
- transformants
- producing
- Prior art date
Links
- 108010023197 Streptokinase Proteins 0.000 title abstract 7
- 108090000623 proteins and genes Proteins 0.000 title abstract 7
- 239000013612 plasmid Substances 0.000 title abstract 3
- 229960005202 streptokinase Drugs 0.000 abstract 6
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 3
- 102000004169 proteins and genes Human genes 0.000 abstract 3
- 125000000539 amino acid group Chemical group 0.000 abstract 2
- 230000002950 deficient Effects 0.000 abstract 2
- 238000011534 incubation Methods 0.000 abstract 2
- 238000004519 manufacturing process Methods 0.000 abstract 2
- 210000004899 c-terminal region Anatomy 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
- C07K14/3153—Streptokinase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP17943289 | 1989-07-11 | ||
JP30795789 | 1989-11-27 | ||
JP9683090 | 1990-04-11 |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0407942T3 true DK0407942T3 (da) | 1996-02-12 |
Family
ID=27308224
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK90113099.7T DK0407942T3 (da) | 1989-07-11 | 1990-07-09 | Streptokinaseproteiner, hertil svarende gener, hertil svarende rekombinante plasmider, hertil svaren de transformanter samt fremgangsmåder til fremstilling heraf |
Country Status (9)
Country | Link |
---|---|
US (1) | US5240845A (de) |
EP (1) | EP0407942B1 (de) |
KR (1) | KR910003104A (de) |
AT (1) | ATE129014T1 (de) |
AU (1) | AU648029B2 (de) |
CA (1) | CA2020828A1 (de) |
DE (1) | DE69022901T2 (de) |
DK (1) | DK0407942T3 (de) |
ES (1) | ES2078925T3 (de) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5240845A (en) * | 1989-07-11 | 1993-08-31 | Otsuka Pharmaceutical Factory, Ltd. | Mutated streptokinase proteins |
GB9201013D0 (en) * | 1992-01-17 | 1992-03-11 | Animal Health Inst | Vaccines |
US6335160B1 (en) * | 1995-02-17 | 2002-01-01 | Maxygen, Inc. | Methods and compositions for polypeptide engineering |
CN1035193C (zh) * | 1994-04-04 | 1997-06-18 | 上海医科大学 | 一种制备重组链激酶的方法 |
ATE386811T1 (de) | 1996-04-05 | 2008-03-15 | Novartis Vaccines & Diagnostic | Alphaviren-vektors mit eine reduzierte inhibierung der synthese von zellmakromolekülen |
AU1829599A (en) * | 1997-12-15 | 1999-07-05 | Presidents and Fellows of Harvard College, The | Bacterial fibrin-dependent plasminogen activator |
WO1999057251A2 (en) * | 1998-05-06 | 1999-11-11 | Oklahoma Medical Research Foundation | Thrombolytic agents derived from streptokinase |
GB9819851D0 (en) * | 1998-09-12 | 1998-11-04 | Rolls Royce Plc | Data processing method and system |
US20030044420A1 (en) * | 1999-09-24 | 2003-03-06 | Mccormick Alison A. | Self antigen vaccines for treating B cell lymphomas and other cancers |
US7084256B2 (en) * | 1999-09-24 | 2006-08-01 | Large Scale Biology Corporation | Self antigen vaccines for treating B cell lymphomas and other cancers |
KR20160110544A (ko) * | 2008-06-04 | 2016-09-21 | 그리폴스 테라퓨틱스 인코포레이티드 | 플라스민의 제조를 위한 조성물, 방법 및 키트 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU561372B2 (en) * | 1983-10-10 | 1987-05-07 | Board Of Regents Of The University Of Oklahoma, The | Streptokinase-coding recombinant vectors |
DD250546A1 (de) * | 1983-12-16 | 1987-10-14 | Adw Ddr | Verfahren zur fermentativen herstellung einer streptokinase |
EP0210279B1 (de) * | 1985-01-25 | 1991-08-14 | Sagami Chemical Research Center | Stabilisierte menschliche prourokinase |
US5219569A (en) * | 1985-04-22 | 1993-06-15 | Genentech, Inc. | Protease resistant urokinase |
US5240845A (en) * | 1989-07-11 | 1993-08-31 | Otsuka Pharmaceutical Factory, Ltd. | Mutated streptokinase proteins |
-
1990
- 1990-07-06 US US07/549,049 patent/US5240845A/en not_active Expired - Fee Related
- 1990-07-09 AU AU58806/90A patent/AU648029B2/en not_active Ceased
- 1990-07-09 ES ES90113099T patent/ES2078925T3/es not_active Expired - Lifetime
- 1990-07-09 DE DE69022901T patent/DE69022901T2/de not_active Expired - Fee Related
- 1990-07-09 DK DK90113099.7T patent/DK0407942T3/da active
- 1990-07-09 EP EP90113099A patent/EP0407942B1/de not_active Expired - Lifetime
- 1990-07-09 AT AT90113099T patent/ATE129014T1/de not_active IP Right Cessation
- 1990-07-10 CA CA002020828A patent/CA2020828A1/en not_active Abandoned
- 1990-07-11 KR KR1019900010501A patent/KR910003104A/ko not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CA2020828A1 (en) | 1991-01-12 |
AU5880690A (en) | 1991-01-17 |
EP0407942B1 (de) | 1995-10-11 |
EP0407942A2 (de) | 1991-01-16 |
US5240845A (en) | 1993-08-31 |
AU648029B2 (en) | 1994-04-14 |
DE69022901T2 (de) | 1996-06-13 |
KR910003104A (ko) | 1991-02-26 |
DE69022901D1 (de) | 1995-11-16 |
ATE129014T1 (de) | 1995-10-15 |
EP0407942A3 (en) | 1991-09-04 |
ES2078925T3 (es) | 1996-01-01 |
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