ATE129014T1 - Streptokinase-proteine, entsprechende gene, entsprechende plasmide und verfahren zu deren herstellung. - Google Patents

Streptokinase-proteine, entsprechende gene, entsprechende plasmide und verfahren zu deren herstellung.

Info

Publication number
ATE129014T1
ATE129014T1 AT90113099T AT90113099T ATE129014T1 AT E129014 T1 ATE129014 T1 AT E129014T1 AT 90113099 T AT90113099 T AT 90113099T AT 90113099 T AT90113099 T AT 90113099T AT E129014 T1 ATE129014 T1 AT E129014T1
Authority
AT
Austria
Prior art keywords
streptokinase
amino acid
transformant
acid sequence
primary amino
Prior art date
Application number
AT90113099T
Other languages
English (en)
Inventor
Setsuro Fujii
Tamiki Katano
Eiji Majima
Koichi Ogino
Kenji Ono
Yasuyo Sakata
Tsutomu Uenoyama
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Application granted granted Critical
Publication of ATE129014T1 publication Critical patent/ATE129014T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C07K14/3153—Streptokinase
AT90113099T 1989-07-11 1990-07-09 Streptokinase-proteine, entsprechende gene, entsprechende plasmide und verfahren zu deren herstellung. ATE129014T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP17943289 1989-07-11
JP30795789 1989-11-27
JP9683090 1990-04-11

Publications (1)

Publication Number Publication Date
ATE129014T1 true ATE129014T1 (de) 1995-10-15

Family

ID=27308224

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90113099T ATE129014T1 (de) 1989-07-11 1990-07-09 Streptokinase-proteine, entsprechende gene, entsprechende plasmide und verfahren zu deren herstellung.

Country Status (9)

Country Link
US (1) US5240845A (de)
EP (1) EP0407942B1 (de)
KR (1) KR910003104A (de)
AT (1) ATE129014T1 (de)
AU (1) AU648029B2 (de)
CA (1) CA2020828A1 (de)
DE (1) DE69022901T2 (de)
DK (1) DK0407942T3 (de)
ES (1) ES2078925T3 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5240845A (en) * 1989-07-11 1993-08-31 Otsuka Pharmaceutical Factory, Ltd. Mutated streptokinase proteins
GB9201013D0 (en) * 1992-01-17 1992-03-11 Animal Health Inst Vaccines
US6335160B1 (en) * 1995-02-17 2002-01-01 Maxygen, Inc. Methods and compositions for polypeptide engineering
CN1035193C (zh) * 1994-04-04 1997-06-18 上海医科大学 一种制备重组链激酶的方法
DE69738521T2 (de) 1996-04-05 2009-05-07 Novartis Vaccines and Diagnostics, Inc., Emeryville Alphaviren-vektors mit einer reduzierten inhibierung der synthese von zellmakromolekülen
WO1999031247A1 (en) * 1997-12-15 1999-06-24 The Presidents And Fellows Of Harvard College Bacterial fibrin-dependent plasminogen activator
EP1078044A2 (de) * 1998-05-06 2001-02-28 Oklahoma Medical Research Foundation Thrombolytische agentien aus streptokinase
GB9819851D0 (en) * 1998-09-12 1998-11-04 Rolls Royce Plc Data processing method and system
US20030044420A1 (en) * 1999-09-24 2003-03-06 Mccormick Alison A. Self antigen vaccines for treating B cell lymphomas and other cancers
US7084256B2 (en) * 1999-09-24 2006-08-01 Large Scale Biology Corporation Self antigen vaccines for treating B cell lymphomas and other cancers
NZ589557A (en) * 2008-06-04 2012-08-31 Talecris Biotherapeutics Inc Immobilised streptokinase, method and kit for preparing plasmin

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU561372B2 (en) * 1983-10-10 1987-05-07 Board Of Regents Of The University Of Oklahoma, The Streptokinase-coding recombinant vectors
DD250546A1 (de) * 1983-12-16 1987-10-14 Adw Ddr Verfahren zur fermentativen herstellung einer streptokinase
DE3680838D1 (de) * 1985-01-25 1991-09-19 Sagami Chem Res Stabilisierte menschliche prourokinase.
US5219569A (en) * 1985-04-22 1993-06-15 Genentech, Inc. Protease resistant urokinase
US5240845A (en) * 1989-07-11 1993-08-31 Otsuka Pharmaceutical Factory, Ltd. Mutated streptokinase proteins

Also Published As

Publication number Publication date
EP0407942B1 (de) 1995-10-11
ES2078925T3 (es) 1996-01-01
US5240845A (en) 1993-08-31
AU648029B2 (en) 1994-04-14
DE69022901D1 (de) 1995-11-16
AU5880690A (en) 1991-01-17
DK0407942T3 (da) 1996-02-12
EP0407942A2 (de) 1991-01-16
KR910003104A (ko) 1991-02-26
EP0407942A3 (en) 1991-09-04
DE69022901T2 (de) 1996-06-13
CA2020828A1 (en) 1991-01-12

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee