DK0405858T3 - Kontrol af akkumulering af aberrante ekspressionsvektorer under fermenteringsprocedurer - Google Patents
Kontrol af akkumulering af aberrante ekspressionsvektorer under fermenteringsprocedurerInfo
- Publication number
- DK0405858T3 DK0405858T3 DK90306853.4T DK90306853T DK0405858T3 DK 0405858 T3 DK0405858 T3 DK 0405858T3 DK 90306853 T DK90306853 T DK 90306853T DK 0405858 T3 DK0405858 T3 DK 0405858T3
- Authority
- DK
- Denmark
- Prior art keywords
- accumulation
- during fermentation
- expression vectors
- control
- aberrant expression
- Prior art date
Links
- 239000013604 expression vector Substances 0.000 title abstract 3
- 230000001594 aberrant effect Effects 0.000 title abstract 2
- 238000009825 accumulation Methods 0.000 title abstract 2
- 238000000855 fermentation Methods 0.000 title abstract 2
- 230000004151 fermentation Effects 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 229940088710 antibiotic agent Drugs 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/61—Growth hormone [GH], i.e. somatotropin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/67—General methods for enhancing the expression
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Endocrinology (AREA)
- Toxicology (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Alcoholic Beverages (AREA)
- Fertilizers (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- General Preparation And Processing Of Foods (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US37157989A | 1989-06-26 | 1989-06-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0405858T3 true DK0405858T3 (da) | 1995-09-04 |
Family
ID=23464539
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK90306853.4T DK0405858T3 (da) | 1989-06-26 | 1990-06-22 | Kontrol af akkumulering af aberrante ekspressionsvektorer under fermenteringsprocedurer |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US5824496A (hu) |
| EP (1) | EP0405858B1 (hu) |
| JP (1) | JPH0347081A (hu) |
| AT (1) | ATE125300T1 (hu) |
| AU (1) | AU617057B2 (hu) |
| CA (1) | CA2019696A1 (hu) |
| DE (1) | DE69020968T2 (hu) |
| DK (1) | DK0405858T3 (hu) |
| ES (1) | ES2076318T3 (hu) |
| GR (1) | GR3017703T3 (hu) |
| HU (1) | HUT54415A (hu) |
| IE (1) | IE67799B1 (hu) |
| IL (1) | IL94847A0 (hu) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5395761A (en) * | 1991-11-27 | 1995-03-07 | Eli Lilly And Company | Plasmid pHKY334, an expression vector for EK-BGH and host cells transformed therewith |
| US6406855B1 (en) | 1994-02-17 | 2002-06-18 | Maxygen, Inc. | Methods and compositions for polypeptide engineering |
| US6335160B1 (en) | 1995-02-17 | 2002-01-01 | Maxygen, Inc. | Methods and compositions for polypeptide engineering |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS55127986A (en) * | 1979-03-26 | 1980-10-03 | Agency Of Ind Science & Technol | Bacteria pretreatment with antibiotic inhibiting synthesis of cell wall |
| US4529695A (en) * | 1981-06-18 | 1985-07-16 | Wisconsin Alumni Research Foundation | Recombinant cloning vector, host for the vector, and method for using same |
| CA1206433A (en) * | 1982-08-06 | 1986-06-24 | Channing R. Robertson | Production of biological products using resting cells |
| EP0178764A1 (en) * | 1984-08-28 | 1986-04-23 | Genex Corporation | Method of stabilizing a host microorganism/expression vector system for large scale production of proteins |
-
1990
- 1990-06-22 AU AU57805/90A patent/AU617057B2/en not_active Ceased
- 1990-06-22 DK DK90306853.4T patent/DK0405858T3/da active
- 1990-06-22 EP EP90306853A patent/EP0405858B1/en not_active Expired - Lifetime
- 1990-06-22 DE DE69020968T patent/DE69020968T2/de not_active Expired - Fee Related
- 1990-06-22 ES ES90306853T patent/ES2076318T3/es not_active Expired - Lifetime
- 1990-06-22 IL IL94847A patent/IL94847A0/xx unknown
- 1990-06-22 AT AT90306853T patent/ATE125300T1/de not_active IP Right Cessation
- 1990-06-22 CA CA002019696A patent/CA2019696A1/en not_active Abandoned
- 1990-06-25 IE IE228990A patent/IE67799B1/en not_active IP Right Cessation
- 1990-06-25 HU HU903975A patent/HUT54415A/hu unknown
- 1990-06-25 JP JP2166529A patent/JPH0347081A/ja active Pending
-
1995
- 1995-08-10 US US08/513,598 patent/US5824496A/en not_active Expired - Fee Related
- 1995-10-11 GR GR950402812T patent/GR3017703T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0347081A (ja) | 1991-02-28 |
| HUT54415A (en) | 1991-02-28 |
| IE902289A1 (en) | 1991-01-16 |
| ES2076318T3 (es) | 1995-11-01 |
| IE67799B1 (en) | 1996-05-01 |
| CA2019696A1 (en) | 1990-12-26 |
| HU903975D0 (en) | 1990-11-28 |
| AU5780590A (en) | 1991-01-03 |
| DE69020968D1 (de) | 1995-08-24 |
| AU617057B2 (en) | 1991-11-14 |
| US5824496A (en) | 1998-10-20 |
| GR3017703T3 (en) | 1996-01-31 |
| IE902289L (en) | 1990-12-26 |
| ATE125300T1 (de) | 1995-08-15 |
| EP0405858A2 (en) | 1991-01-02 |
| DE69020968T2 (de) | 1995-12-21 |
| EP0405858B1 (en) | 1995-07-19 |
| IL94847A0 (en) | 1991-04-15 |
| EP0405858A3 (en) | 1992-04-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP1243650A3 (en) | Process for constructing a cdna library, and a polypeptide and dna coding for the same | |
| ES2142363T3 (es) | Materiales y metodos para la hipersecrecion de aminoacidos. | |
| AU2129592A (en) | Method of characterisation | |
| DK170587A (da) | Fremgangsmaade til udvinding af glykopeptidiske antibiotika | |
| EP0552240A4 (en) | New method of treating depression | |
| DE69739013D1 (de) | Verfahren zur Herstellung sekretorischer KEX2-Derivate | |
| DK0562508T3 (da) | Nyt knogle-relateret protein OSF-2, fremgangsmåde til dets fremstilling samt farmaceutisk præparat med indhold deraf | |
| DK0405858T3 (da) | Kontrol af akkumulering af aberrante ekspressionsvektorer under fermenteringsprocedurer | |
| AU4608689A (en) | Process for the conjugative transfer of mobilizable vectors from e. coli into gram-positive bacteria and vectors which are suitable for this | |
| HUT55800A (en) | Process for producing anticoagulant peptides | |
| EP0911415A3 (en) | Microbiological manufacture of L-ascorbic acid | |
| AU5971090A (en) | Metalloproteinase inhibitor sequence recombinant vector system for using same and recombinant-dna method for the manufacture of same | |
| EP0638515A3 (de) | Verfahren zur Aufarbeitung von Dünnsäure. | |
| GR3030321T3 (en) | Method for casein finishing of leather. | |
| DE69329540D1 (de) | Verfahren zur Herstellung von Proteaseinhibitoren | |
| TW242161B (hu) | ||
| DE60036134D1 (de) | Methoden und materialien fur genexpression | |
| ATE269903T1 (de) | Verbessertes, induktionsfreies verfahren zur gentechnischen herstellung von glutarylamidase | |
| FR2689502B1 (fr) | Procédé de production de 1, 1-dichloro-1-fluoréthane ("141b") stabilisé et produit obtenu. | |
| FR2706494B1 (fr) | Procédé pour la teinture dégradée de cuirs. | |
| DE69404641D1 (de) | Verfahren zur herstellung von 3,4-dihalogeno-1,2-epoxybutanen ausgehend von 3,4-epoxy-1-buten | |
| DE69017787D1 (de) | Verfahren zur Herstellung von Methylendi(phenylurethan). | |
| HU9200745D0 (en) | Process for the production of 2,2-dimethyl-2,3-dihydro-benzofurane-7-carbonic acid derivatives | |
| DE69014240D1 (de) | Verfahren zur Herstellung von Methylendi(phenylurethan). | |
| HUT67823A (en) | Process for the production of leather treating substance from environment-damaging, protein sewage |